There are 8 ways to get from Prague to Palermo by plane, train (Trenitalia), bus, car, ferry, train, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Palermo Airport
best- Fly from Václav Havel Airport Prague (PRG) to Palermo Airport (PMO)plane PRG - PMO
5h 35m€70–219Fly to Trapani Airport, bus
cheapest- Fly from Václav Havel Airport Prague (PRG) to Trapani Airport (TPS)plane PRG - TPS
- Take the bus from Trapani Birgi Airport to Palermo Via Belgio/Via dei Nebrodibus
10h 12m€68–294Train
- Take the train from Praha Hlavni Nadrazi to Linz/Donau Hbftrain Ec
- Take the train from Linz/Donau Hbf to Innsbruck Hauptbahnhoftrain Rjx / ...
- Take the train from Innsbruck Hauptbahnhof to Bolzano Bozentrain Re
- Take the train from Bolzano Bozen to Roma Terminitrain Fr
- Take the train from Roma Termini to Palermo Centraletrain Ic
28h 57m€269–563Bus
- Take the bus from Prague to Munich central bus stationbus FlixBus 183 / ...
- Take the bus from München Hackerbrücke to Palermo Piazza Cairolibus
33h 43m€252–365Drive, ferry
- Drive from Prague to Naples Beverellocar
- Take the ferry from Naples Beverello to Port of Palermoferry
21h 53m€260–402Fly to Catania–Fontanarossa Airport, bus
- Fly from Václav Havel Airport Prague (PRG) to Catania–Fontanarossa Airport (CTA)plane PRG - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazellobus
8h 12m€68–200Train, night train
- Take the train from Praha Hlavni Nadrazi to Linz/Donau Hbftrain Ec
- Take the nighttrain from Linz/Donau Hbf to Venezia S. Lucianighttrain Nj
- Take the train from Venezia S. Lucia to Roma Terminitrain Fr
- Take the train from Roma Termini to Palermo Centraletrain Ic
31h 34m€219–490Bus via Rome
- Take the bus from Praha, Hlavní Nádraží to Roma, Autostazione Tiburtinabus N1533
- Take the bus from Roma, Autostazione Tiburtina to Palermobus N592
35h 55m€197–304
Prague to Palermo by train
Comparing Your Travel Options
The cheapest way to get from Prague to Palermo is to fly and bus which costs €65 - €200 and takes 8h 12m.
The fastest way to get from Prague to Palermo is to fly which takes 5h 35m and costs €70 - €220.
No, there is no direct bus from Prague to Palermo. However, there are services departing from Prague and arriving at Palermo Piazza Cairoli via München Hackerbrücke. The journey, including transfers, takes approximately 33h 43m.
No, there is no direct train from Prague to Palermo. However, there are services departing from Praha Hlavni Nadrazi and arriving at Palermo Centrale via Linz/Donau Hbf, Innsbruck Hauptbahnhof, Bolzano Bozen and Roma Termini. The journey, including transfers, takes approximately 28h 57m.
The distance between Prague and Palermo is 1374 km.
The best way to get from Prague to Palermo without a car is to train which takes 28h 57m and costs €260 - €600.
It takes approximately 5h 35m to get from Prague to Palermo, including transfers.
Prague to Palermo bus services, operated by FlixBus, depart from Prague station.
Prague to Palermo train services, operated by ÖBB EuroCity, depart from Praha Hlavni Nadrazi station.
The best way to get from Prague to Palermo is to fly which takes 5h 35m and costs €70 - €220. Alternatively, you can train, which costs €260 - €600 and takes 28h 57m, you could also bus, which costs €250 - €370 and takes 33h 43m.
What companies run services between Prague, Czechia and Palermo, Italy?
Ulendo Airlink, Ryanair, and Lufthansa fly from Václav Havel Airport Prague (PRG) to Palermo Airport (PMO) 3 times a day. Alternatively, you can take a train from Praha Hlavni Nadrazi to Palermo Centrale via Linz/Donau Hbf, Innsbruck Hauptbahnhof, Bolzano Bozen, and Roma Termini in around 28h 57m.
- Website
- ryanair.com
Flights from Václav Havel Airport Prague to Palermo Airport
- Ave. Duration
- 2h 15m
- When
- Tuesday and Saturday
- Estimated price
- €70–200
Flights from Václav Havel Airport Prague to Trapani Airport via Milan Bergamo
- Ave. Duration
- 5h 50m
- When
- Sunday and Thursday
- Estimated price
- €65–280
Flights from Václav Havel Airport Prague to Trapani Airport via Pisa
- Ave. Duration
- 5h 50m
- When
- Wednesday and Saturday
- Estimated price
- €65–280
Flights from Václav Havel Airport Prague to Trapani Airport via Bologna
- Ave. Duration
- 7h 5m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- €60–280
Flights from Václav Havel Airport Prague to Trapani Airport via Bari
- Ave. Duration
- 9h 45m
- When
- Monday
- Estimated price
- €65–280
Flights from Václav Havel Airport Prague to Trapani Airport via Rome
- Ave. Duration
- 6h 25m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- €100–290
Flights from Václav Havel Airport Prague to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 20m
- When
- Monday and Friday
- Estimated price
- €55–140
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Linz/Donau Hbf
- Ave. Duration
- 3h 45m
- Frequency
- Every 4 hours
- Estimated price
- €60–90
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Linz/Donau Hbf
- Ave. Duration
- 3h 45m
- Frequency
- Every 4 hours
- Estimated price
- €60–90
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Prague to Munich central bus station
- Ave. Duration
- 5h 30m
- Frequency
- Every 4 hours
- Estimated price
- €30–45
- Website
- Flixbus
Bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazello
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- €17–26
- Website
- Flixbus
Bus from Praha, Hlavní Nádraží to Roma, Autostazione Tiburtina
- Ave. Duration
- 21h
- Frequency
- Once daily
- Estimated price
- €110–180
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Palermo
- Ave. Duration
- 13h 55m
- Frequency
- Once daily
- Estimated price
- €80–130
- Website
- Flixbus
- Phone
- +39.081.496.444
- [email protected]
- Website
- Grimaldi Lines
Ferry from Naples Beverello to Port of Palermo
- Ave. Duration
- 7h 30m
- Frequency
- 6 times a week
- Estimated price
- €30–70
- Website
- Grimaldi Lines
Want to know more about travelling around Italy
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Booking & Getting There
Prague to Palermo bus services, operated by FlixBus, arrive at Munich central bus station.
Prague to Palermo train services, operated by ÖBB EuroCity, arrive at Linz/Donau Hbf station.
Book your Prague to Palermo train tickets online with Omio.
Book your Prague to Palermo bus tickets online with Omio.
There are 6185+ hotels available in Palermo.













