There are 8 ways to get from Prague to Palermo by plane, train (Trenitalia), bus, car, ferry, train, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Palermo Airport
best- Fly from Václav Havel Airport Prague (PRG) to Palermo Airport (PMO)plane PRG - PMO
5h 35m€65–210Train
- Take the train from Praha Hlavni Nadrazi to Linz/Donau Hbftrain Ec
- Take the train from Linz/Donau Hbf to Innsbruck Hauptbahnhoftrain Rjx / ...
- Take the train from Innsbruck Hauptbahnhof to Bolzano Bozentrain Re
- Take the train from Bolzano Bozen to Roma Terminitrain Fr
- Take the train from Roma Termini to Palermo Centraletrain Ic
29h 2m€285–647Bus
- Take the bus from Prague Florenc Central Bus Station to Munich Central Bus Stationbus : Munich Central Bus Station - Prague Central Bus Station / ...
- Take the bus from München Hackerbrücke to Palermo Piazza Cairolibus
32h 58m€255–373Drive, ferry
- Drive from Prague to Naples Beverellocar
- Take the ferry from Naples Beverello to Port of Palermoferry
21h 53m€261–391Fly to Trapani Airport, bus
- Fly from Václav Havel Airport Prague (PRG) to Trapani Airport (TPS)plane PRG - TPS
- Take the bus from Trapani Birgi Airport to Palermo Via Belgio/Via dei Nebrodibus
10h 12m€73–284Fly to Catania–Fontanarossa Airport, bus
- Fly from Václav Havel Airport Prague (PRG) to Catania–Fontanarossa Airport (CTA)plane PRG - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazellobus
8h 12m€68–199Train, night train
- Take the train from Praha Hlavni Nadrazi to Linz/Donau Hbftrain Ec
- Take the nighttrain from Linz/Donau Hbf to Venezia S. Lucianighttrain Nj
- Take the train from Venezia S. Lucia to Roma Terminitrain Fr
- Take the train from Roma Termini to Palermo Centraletrain Ic
31h 34m€236–569Bus via Rome
- Take the bus from Praha, Hlavní Nádraží to Roma, Autostazione Tiburtinabus N1533
- Take the bus from Roma, Autostazione Tiburtina to Palermobus N592
35h 55m€181–289
Prague to Palermo by train
Questions & Answers
The cheapest way to get from Prague to Palermo is to fly and bus which costs €65 - €200 and takes 8h 12m.
The fastest way to get from Prague to Palermo is to fly which takes 5h 35m and costs €65 - €210.
No, there is no direct bus from Prague station to Palermo. However, there are services departing from Prague Florenc Central Bus Station and arriving at Palermo Piazza Cairoli via München Hackerbrücke. The journey, including transfers, takes approximately 32h 58m.
No, there is no direct train from Prague to Palermo. However, there are services departing from Praha Hlavni Nadrazi and arriving at Palermo Centrale via Linz/Donau Hbf, Innsbruck Hauptbahnhof, Bolzano Bozen and Roma Termini. The journey, including transfers, takes approximately 29h 2m.
The distance between Prague and Palermo is 1374 km.
The best way to get from Prague to Palermo without a car is to train which takes 29h 2m and costs €280 - €650.
It takes approximately 5h 35m to get from Prague to Palermo, including transfers.
Prague to Palermo bus services, operated by RegioJet, depart from Prague Florenc Central Bus Station.
Prague to Palermo train services, operated by ÖBB EuroCity, depart from Praha Hlavni Nadrazi station.
The best way to get from Prague to Palermo is to fly which takes 5h 35m and costs €65 - €210. Alternatively, you can train, which costs €280 - €650 and takes 29h 2m, you could also bus, which costs €250 - €380 and takes 32h 58m.
What companies run services between Prague, Czechia and Palermo, Italy?
Ulendo Airlink, Ryanair, and Lufthansa fly from Václav Havel Airport Prague (PRG) to Palermo Airport (PMO) 3 times a day. Alternatively, you can take a train from Praha Hlavni Nadrazi to Palermo Centrale via Linz/Donau Hbf, Innsbruck Hauptbahnhof, Bolzano Bozen, and Roma Termini in around 29h 2m.
- Website
- ryanair.com
Flights from Václav Havel Airport Prague to Palermo Airport
- Ave. Duration
- 2h 15m
- When
- Tuesday and Saturday
- Estimated price
- €60–190
Flights from Václav Havel Airport Prague to Trapani Airport via Milan Bergamo
- Ave. Duration
- 5h 50m
- When
- Sunday and Thursday
- Estimated price
- €65–280
Flights from Václav Havel Airport Prague to Trapani Airport via Bologna
- Ave. Duration
- 7h 5m
- When
- Tuesday and Friday
- Estimated price
- €65–270
Flights from Václav Havel Airport Prague to Trapani Airport via Bari
- Ave. Duration
- 10h 45m
- When
- Monday
- Estimated price
- €65–280
Flights from Václav Havel Airport Prague to Trapani Airport via Rome
- Ave. Duration
- 6h 25m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- €95–290
Flights from Václav Havel Airport Prague to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 20m
- When
- Monday and Friday
- Estimated price
- €55–160
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Linz/Donau Hbf
- Ave. Duration
- 3h 45m
- Frequency
- Every 4 hours
- Estimated price
- €60–110
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Linz/Donau Hbf
- Ave. Duration
- 3h 45m
- Frequency
- Every 4 hours
- Estimated price
- €60–110
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
- Phone
- +420 222 222 221
- [email protected]
- Website
- RegioJet
Bus from Prague Florenc Central Bus Station to Munich Central Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- 5 times a day
- Estimated price
- €25–40
- Website
- RegioJet
- Phone
- +39.081.496.444
- [email protected]
- Website
- Grimaldi Lines
Ferry from Naples Beverello to Port of Palermo
- Ave. Duration
- 7h 30m
- Frequency
- 6 times a week
- Estimated price
- €35–65
- Website
- Grimaldi Lines
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More Questions & Answers
Prague to Palermo bus services, operated by RegioJet, arrive at Munich Central Bus Station.
Prague to Palermo train services, operated by ÖBB EuroCity, arrive at Linz/Donau Hbf station.
Book your Prague to Palermo train tickets online with Omio.
Book your Prague to Palermo bus tickets online with Omio.
There are 6323+ hotels available in Palermo.









