There are 9 ways to get from Prague to Palermo (Region) by plane, bus, train (Trenitalia), car, ferry, train, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Václav Havel Airport Prague to Palermo Airport, bus
best- Fly from Václav Havel Airport Prague (PRG) to Palermo Airport (PMO)plane PRG - PMO
- Take the bus from Palermo to Vicaribus
8h 4mFly Václav Havel Airport Prague to Catania–Fontanarossa Airport, train
cheapest- Fly from Václav Havel Airport Prague (PRG) to Catania–Fontanarossa Airport (CTA)plane PRG - CTA
- Take the train from Catania Aeroporto Fontanarossa to Roccapalumba-Aliatrain
8h 29m€107–237Train
- Take the train from Praha Hlavni Nadrazi to Wien Hbftrain Rj
- Take the train from Wien Hbf to Treviso Centraletrain Rjx
- Take the train from Treviso Centrale to Roma Terminitrain Fr
- Take the train from Roma Termini to Termini Imeresetrain Ic
30h 2m€294–509Bus
- Take the bus from Prague to Munich central bus stationbus
- Take the bus from München Hackerbrücke to Palermo Piazza Cairolibus
- Take the bus from Palermo to Vicaribus
36h 16mDrive, ferry
- Drive from Prague to Naples Beverellocar
- Take the ferry from Naples Beverello to Port of Palermoferry
- Drive from Port of Palermo to Palermo (Region)car
22h 55m€268–416Fly Václav Havel Airport Prague to Trapani Airport, bus
- Fly from Václav Havel Airport Prague (PRG) to Trapani Airport (TPS)plane PRG - TPS
- Take the bus from Trapani Birgi Airport to Palermo Terminal Busbus
- Take the bus from Palermo to Vicaribus
12h 52mTrain to Vienna International Airport, fly to Palermo Airport, bus
- Take the train from Praha Hlavni Nadrazi to Wien Hbftrain
- Fly from Vienna International Airport (VIE) to Palermo Airport (PMO)plane VIE - PMO
- Take the bus from Palermo to Vicaribus
11h 49mTrain, night train, bus
- Take the train from Praha Hlavni Nadrazi to Linz/Donau Hbftrain Ec
- Take the nighttrain from Linz/Donau Hbf to Venezia S. Lucianighttrain Nj
- Take the train from Venezia S. Lucia to Roma Terminitrain Fr
- Take the train from Roma Termini to Palermo Centraletrain Ic
- Take the bus from Palermo to Vicaribus
33h 42mBus via Rome
- Take the bus from Praha, Hlavní Nádraží to Roma, Autostazione Tiburtinabus
- Take the bus from Roma, Autostazione Tiburtina to Palermobus
- Take the bus from Palermo to Vicaribus
38h 30m
Václav Havel Airport Prague (PRG) to Palermo Airport (PMO) flights
Comparing Your Travel Options
The cheapest way to get from Prague to Palermo (Region) is to fly and train which costs €100 - €240 and takes 8h 29m.
The fastest way to get from Prague to Palermo (Region) is to fly and train which takes 8h 29m and costs €100 - €240.
No, there is no direct bus from Prague to Palermo (Region). However, there are services departing from Prague and arriving at Vicari via München Hackerbrücke and Palermo. The journey, including transfers, takes approximately 36h 16m.
No, there is no direct train from Prague to Palermo (Region). However, there are services departing from Praha Hlavni Nadrazi and arriving at Roccapalumba-Alia via Wien Hbf, Treviso Centrale, Roma Termini and Termini Imerese. The journey, including transfers, takes approximately 30h 2m.
The distance between Prague and Palermo (Region) is 1430 km.
The best way to get from Prague to Palermo (Region) without a car is to train which takes 30h 2m and costs €290 - €550.
It takes approximately 8h 4m to get from Prague to Palermo (Region), including transfers.
Prague to Palermo (Region) bus services, operated by FlixBus, depart from Prague station.
Prague to Palermo (Region) train services, operated by České dráhy (ČD), depart from Praha Hlavni Nadrazi station.
The best way to get from Prague to Palermo (Region) is to train which takes 30h 2m and costs €290 - €550. Alternatively, you can bus, which costs and takes 36h 16m.
What companies run services between Prague, Czechia and Palermo (Region), Sicily, Italy?
You can take a train from Praha Hlavni Nadrazi to Palermo (Region) via Wien Hbf, Treviso Centrale, Roma Termini, Termini Imerese, and Roccapalumba-Alia in around 30h 2m. Alternatively, you can take a bus from Prague to Vicari via Munich central bus station, München Hackerbrücke, Palermo Piazza Cairoli, and Palermo in around 36h 16m.
- Website
- ryanair.com
Flights from Václav Havel Airport Prague to Palermo Airport
- Ave. Duration
- 2h 15m
- When
- Tuesday and Saturday
- Estimated price
- €75–220
Flights from Václav Havel Airport Prague to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 20m
- When
- Monday and Friday
- Estimated price
- €55–130
Flights from Václav Havel Airport Prague to Trapani Airport via Milan Bergamo
- Ave. Duration
- 5h 50m
- When
- Sunday and Thursday
- Estimated price
- €65–280
Flights from Václav Havel Airport Prague to Trapani Airport via Pisa
- Ave. Duration
- 5h 50m
- When
- Saturday
- Estimated price
- €65–280
Flights from Václav Havel Airport Prague to Trapani Airport via Bologna
- Ave. Duration
- 7h 5m
- When
- Tuesday, Wednesday, and Friday
- Estimated price
- €65–280
Flights from Václav Havel Airport Prague to Trapani Airport via Rome
- Ave. Duration
- 6h 25m
- When
- Thursday and Sunday
- Estimated price
- €100–290
Flights from Vienna International Airport to Palermo Airport
- Ave. Duration
- 2h
- When
- Tuesday to Wednesday
- Estimated price
- €45–200
Flights from Vienna International Airport to Palermo Airport via Naples
- Ave. Duration
- 3h 30m
- When
- Tuesday, Wednesday, Friday, and Saturday
- Estimated price
- €45–200
Flights from Vienna International Airport to Palermo Airport via Venice
- Ave. Duration
- 3h 57m
- When
- Friday
- Estimated price
- €45–200
Flights from Vienna International Airport to Palermo Airport via Rome
- Ave. Duration
- 4h
- When
- Thursday and Sunday
- Estimated price
- €45–200
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Palermo Airport via Munich
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- €85–300
Flights from Václav Havel Airport Prague to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- €55–280
- Website
- ita-airways.com
Flights from Václav Havel Airport Prague to Palermo Airport via Munich
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- €85–300
Flights from Vienna International Airport to Palermo Airport
- Ave. Duration
- 1h 55m
- When
- Tuesday, Saturday, and Thursday
- Estimated price
- €85–230
Flights from Vienna International Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €85–230
- Website
- easyjet.com
Flights from Václav Havel Airport Prague to Palermo Airport via Naples
- Ave. Duration
- 4h 27m
- When
- Friday and Sunday
- Estimated price
- €45–220
Flights from Václav Havel Airport Prague to Catania–Fontanarossa Airport via Naples
- Ave. Duration
- 4h 25m
- When
- Sunday
- Estimated price
- €45–210
- Website
- austrian.com
Flights from Vienna International Airport to Palermo Airport
- Ave. Duration
- 1h 55m
- When
- Tuesday, Saturday, and Thursday
- Estimated price
- €85–230
Flights from Vienna International Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €85–230
- Website
- flyulendo.com
Flights from Václav Havel Airport Prague to Palermo Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €65–210
Flights from Václav Havel Airport Prague to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 25m
- When
- Tuesday and Saturday
- Estimated price
- €45–160
- Phone
- +420 221 111 122
- [email protected]
- Website
- Czech Railways (ČD)
Train from Praha Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 4h 12m
- Frequency
- Hourly
- Estimated price
- €32
- Website
- Czech Railways (ČD)
Train from Praha Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 4h 12m
- Frequency
- Hourly
- Estimated price
- €32
- Website
- Czech Railways (ČD)
Train from Praha Hlavni Nadrazi to Linz/Donau Hbf
- Ave. Duration
- 5h 53m
- Frequency
- Twice daily
- Estimated price
- €23
- Website
- Czech Railways (ČD)
- Phone
- +420 222 222 221
- [email protected]
- Website
- RegioJet
Train from Praha Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 4h 17m
- Frequency
- Every 4 hours
- Estimated price
- €19–35
- Website
- RegioJet
Train from Praha Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 4h 17m
- Frequency
- Every 4 hours
- Estimated price
- €19–35
- Website
- RegioJet
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Treviso Centrale to Roma Termini
- Ave. Duration
- 4h 14m
- Frequency
- Twice daily
- Estimated price
- €70–130
- Website
- Trenitalia Frecce
Train from Venezia S. Lucia to Roma Termini
- Ave. Duration
- 3h 59m
- Frequency
- Hourly
- Estimated price
- €70–120
- Website
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Roma Termini to Termini Imerese
- Ave. Duration
- 10h 57m
- Frequency
- 4 times a day
- Estimated price
- €85–170
- Website
- Trenitalia Intercity
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 32m
- Frequency
- 4 times a day
- Estimated price
- €90–170
- Website
- Trenitalia Intercity
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Catania Aeroporto Fontanarossa to Roccapalumba-Alia
- Ave. Duration
- 1h 58m
- Frequency
- Every 2 hours
- Estimated price
- €20–28
- Website
- Trenitalia
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Linz/Donau Hbf
- Ave. Duration
- 3h 45m
- Frequency
- Every 4 hours
- Estimated price
- €74
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Linz/Donau Hbf to Venezia S. Lucia
- Ave. Duration
- 9h 24m
- Frequency
- Twice daily
- Estimated price
- €35–110
- Website
- Nightjet
- Sleeper Carriage
- €100–110
- Couchette Carriage
- €65–80
- Seating Carriage
- €35–45
- Phone
- +39 091-6208000
- [email protected]
- Website
- aziendasicilianatrasporti.it
Bus from Palermo to Vicari
- Ave. Duration
- 1h 10m
- Frequency
- 4 times a day
- Schedules at
- aziendasicilianatrasporti.it
Bus from Palermo to Vicari
- Ave. Duration
- 1h 35m
- Frequency
- Every 3 hours
- Schedules at
- aziendasicilianatrasporti.it
Bus from Palermo to Vicari
- Ave. Duration
- 1h 10m
- Frequency
- 4 times a day
- Schedules at
- aziendasicilianatrasporti.it
Bus from Palermo to Vicari
- Ave. Duration
- 1h 10m
- Frequency
- 4 times a day
- Schedules at
- aziendasicilianatrasporti.it
Bus from Palermo to Vicari
- Ave. Duration
- 1h 35m
- Frequency
- Every 3 hours
- Schedules at
- aziendasicilianatrasporti.it
Bus from Palermo to Vicari
- Ave. Duration
- 1h 35m
- Frequency
- Every 3 hours
- Schedules at
- aziendasicilianatrasporti.it
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Prague to Munich central bus station
- Ave. Duration
- 5h 30m
- Frequency
- Every 4 hours
- Estimated price
- €30–50
- Website
- Flixbus
Bus from Praha, Hlavní Nádraží to Roma, Autostazione Tiburtina
- Ave. Duration
- 21h
- Frequency
- Once daily
- Estimated price
- €120–180
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Palermo
- Ave. Duration
- 13h 55m
- Frequency
- Once daily
- Estimated price
- €85–130
- Website
- Flixbus
- Phone
- +420 222 222 221
- [email protected]
- Website
- RegioJet
Bus from Prague to Munich central bus station
- Ave. Duration
- 4h 45m
- Frequency
- 5 times a day
- Estimated price
- €22–40
- Website
- RegioJet
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Prague to Munich central bus station
- Ave. Duration
- 5h 50m
- Frequency
- Once daily
- Estimated price
- €25–45
- Website
- BlaBlaCar Bus
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from München Hackerbrücke to Palermo Piazza Cairoli
- Ave. Duration
- 27h 6m
- Frequency
- Once a week
- Estimated price
- €230–320
- Website
- Onebus
- Phone
- (+39) 0923 98.11.20
- Website
- Autoservizi Salemi Srl
Bus from Trapani Birgi Airport to Palermo Terminal Bus
- Ave. Duration
- 1h 55m
- Frequency
- 6 times a week
- Estimated price
- €6–10
- Schedules at
- Autoservizi Salemi Srl
- Phone
- +39.081.496.444
- [email protected]
- Website
- Grimaldi Lines
Ferry from Naples Beverello to Port of Palermo
- Ave. Duration
- 7h 30m
- Frequency
- 6 times a week
- Estimated price
- €30–70
- Website
- Grimaldi Lines
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Booking & Getting There
Prague to Palermo (Region) bus services, operated by FlixBus, arrive at Munich central bus station.
Prague to Palermo (Region) train services, operated by České dráhy (ČD), arrive at Wien Hbf station.
There are 1010+ hotels available in Palermo (Region).



















































