There are 8 ways to get from Prague to Palermo (Region) by plane, bus, train (Trenitalia), car, car ferry, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Václav Havel Airport Prague to Palermo Airport, bus
best- Fly from Václav Havel Airport Prague (PRG) to Palermo Airport (PMO)plane PRG - PMO
- Take the bus from Palermo to Vicaribus
8h 15mFly Václav Havel Airport Prague to Catania–Fontanarossa Airport, train
cheapest- Fly from Václav Havel Airport Prague (PRG) to Catania–Fontanarossa Airport (CTA)plane PRG - CTA
- Take the train from Catania Aeroporto Fontanarossa to Roccapalumba-Aliatrain
8h 39m€106–247Train
- Take the train from Praha Hlavni Nadrazi to Wien Hbftrain Rj
- Take the train from Wien Hbf to Pordenonetrain Rjx
- Take the train from Pordenone to Roma Terminitrain
- Take the train from Roma Termini to Termini Imeresetrain Ic
30h 31m€284–530Bus
- Take the bus from Prague to Munich central bus stationbus
- Take the bus from München Hackerbrücke to Palermo Piazza Cairolibus
- Take the bus from Palermo to Vicaribus
36h 16mDrive, car ferry
- Drive from Prague to Villa S. Giovannicar
- Take the carferry from Villa S. Giovanni to Tresmestiericarferry
- Drive from Tresmestieri to Palermo (Region)car
21h 57m€399–586Fly Václav Havel Airport Prague to Trapani Airport, bus
- Fly from Václav Havel Airport Prague (PRG) to Trapani Airport (TPS)plane PRG - TPS
- Take the bus from Trapani Birgi Airport to Palermo Terminal Busbus
- Take the bus from Palermo to Vicaribus
13h 11mTrain to Vienna International Airport, fly to Palermo Airport, bus
- Take the train from Praha Hlavni Nadrazi to Wien Hbftrain
- Fly from Vienna International Airport (VIE) to Palermo Airport (PMO)plane VIE - PMO
- Take the bus from Palermo to Vicaribus
12h 5mBus via Rome
- Take the bus from Praha, Hlavní Nádraží to Roma, Autostazione Tiburtinabus
- Take the bus from Roma, Autostazione Tiburtina to Palermobus
- Take the bus from Palermo to Vicaribus
38h 30m
Václav Havel Airport Prague (PRG) to Palermo Airport (PMO) flights
Comparing Your Travel Options
The cheapest way to get from Prague to Palermo (Region) is to fly and train which costs €100 - €250 and takes 8h 39m.
The fastest way to get from Prague to Palermo (Region) is to fly and train which takes 8h 39m and costs €100 - €250.
No, there is no direct bus from Prague to Palermo (Region). However, there are services departing from Prague and arriving at Vicari via München Hackerbrücke and Palermo. The journey, including transfers, takes approximately 36h 16m.
No, there is no direct train from Prague to Palermo (Region). However, there are services departing from Praha Hlavni Nadrazi and arriving at Roccapalumba-Alia via Wien Hbf, Pordenone, Roma Termini and Termini Imerese. The journey, including transfers, takes approximately 30h 31m.
The distance between Prague and Palermo (Region) is 1430 km.
The best way to get from Prague to Palermo (Region) without a car is to train which takes 30h 31m and costs €280 - €550.
It takes approximately 8h 15m to get from Prague to Palermo (Region), including transfers.
Prague to Palermo (Region) bus services, operated by FlixBus, depart from Prague station.
Prague to Palermo (Region) train services, operated by České dráhy (ČD), depart from Praha Hlavni Nadrazi station.
The best way to get from Prague to Palermo (Region) is to train which takes 30h 31m and costs €280 - €550. Alternatively, you can bus, which costs and takes 36h 16m.
What companies run services between Prague, Czechia and Palermo (Region), Sicily, Italy?
You can take a train from Praha Hlavni Nadrazi to Palermo (Region) via Wien Hbf, Pordenone, Roma Termini, Termini Imerese, and Roccapalumba-Alia in around 30h 31m. Alternatively, you can take a bus from Prague to Vicari via Munich central bus station, München Hackerbrücke, Palermo Piazza Cairoli, and Palermo in around 36h 16m.
- Website
- ryanair.com
Flights from Václav Havel Airport Prague to Palermo Airport
- Ave. Duration
- 2h 15m
- When
- Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- €65–180
Flights from Václav Havel Airport Prague to Palermo Airport via Bologna
- Ave. Duration
- 5h 5m
- When
- Monday
- Estimated price
- €65–180
Flights from Václav Havel Airport Prague to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 30m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €55–140
Flights from Václav Havel Airport Prague to Trapani Airport via Milan Bergamo
- Ave. Duration
- 7h 23m
- When
- Sunday, Monday, Wednesday, and Friday
- Estimated price
- €65–270
Flights from Václav Havel Airport Prague to Trapani Airport via Rome
- Ave. Duration
- 6h 50m
- When
- Monday and Friday
- Estimated price
- €95–280
Flights from Vienna International Airport to Palermo Airport
- Ave. Duration
- 2h
- When
- Monday, Tuesday, and Sunday
- Estimated price
- €45–210
Flights from Vienna International Airport to Palermo Airport via Rome
- Ave. Duration
- 4h 2m
- When
- Monday and Friday
- Estimated price
- €45–210
Flights from Vienna International Airport to Palermo Airport via Bologna
- Ave. Duration
- 4h 15m
- When
- Friday
- Estimated price
- €45–210
Flights from Vienna International Airport to Palermo Airport via Bari
- Ave. Duration
- 4h 25m
- When
- Friday and Sunday
- Estimated price
- €45–210
- Website
- ita-airways.com
Flights from Václav Havel Airport Prague to Palermo Airport via Munich
- Ave. Duration
- 4h 50m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €80–280
Flights from Václav Havel Airport Prague to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- €75–270
Flights from Vienna International Airport to Palermo Airport
- Ave. Duration
- 1h 55m
- When
- Thursday
- Estimated price
- €65–260
Flights from Vienna International Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Monday to Saturday
- Estimated price
- €65–270
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Palermo Airport via Munich
- Ave. Duration
- 4h 50m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €80–280
Flights from Václav Havel Airport Prague to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- €50–270
- Website
- flyulendo.com
Flights from Václav Havel Airport Prague to Palermo Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €60–200
Flights from Václav Havel Airport Prague to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 30m
- When
- Tuesday and Saturday
- Estimated price
- €45–160
- Website
- austrian.com
Flights from Vienna International Airport to Palermo Airport
- Ave. Duration
- 1h 55m
- When
- Thursday
- Estimated price
- €65–260
Flights from Vienna International Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Monday to Saturday
- Estimated price
- €65–270
- Phone
- +420 221 111 122
- [email protected]
- Website
- Czech Railways (ČD)
Train from Praha Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 4h 13m
- Frequency
- Every 4 hours
- Estimated price
- €35–55
- Website
- Czech Railways (ČD)
Train from Praha Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 4h 13m
- Frequency
- Every 4 hours
- Estimated price
- €35–55
- Website
- Czech Railways (ČD)
- Phone
- +420 222 222 221
- [email protected]
- Website
- RegioJet
Train from Praha Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 4h 17m
- Frequency
- 4 times a day
- Estimated price
- €19–35
- Website
- RegioJet
Train from Praha Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 4h 17m
- Frequency
- 4 times a day
- Estimated price
- €19–35
- Website
- RegioJet
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Pordenone to Roma Termini
- Ave. Duration
- 5h 5m
- Frequency
- Twice daily
- Estimated price
- €65–120
- Website
- Italo Treno
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Pordenone to Roma Termini
- Ave. Duration
- 5h 6m
- Frequency
- Once daily
- Estimated price
- €80–140
- Website
- Trenitalia Frecce
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Roma Termini to Termini Imerese
- Ave. Duration
- 10h 57m
- Frequency
- Twice daily
- Estimated price
- €90–170
- Website
- Trenitalia Intercity
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Catania Aeroporto Fontanarossa to Roccapalumba-Alia
- Ave. Duration
- 1h 58m
- Frequency
- Every 4 hours
- Estimated price
- €19–28
- Website
- Trenitalia
- Phone
- +39 091-6208000
- [email protected]
- Website
- aziendasicilianatrasporti.it
Bus from Palermo to Vicari
- Ave. Duration
- 1h 10m
- Frequency
- 4 times a day
- Schedules at
- aziendasicilianatrasporti.it
Bus from Palermo to Vicari
- Ave. Duration
- 1h 35m
- Frequency
- Every 3 hours
- Schedules at
- aziendasicilianatrasporti.it
Bus from Palermo to Vicari
- Ave. Duration
- 1h 10m
- Frequency
- 4 times a day
- Schedules at
- aziendasicilianatrasporti.it
Bus from Palermo to Vicari
- Ave. Duration
- 1h 10m
- Frequency
- 4 times a day
- Schedules at
- aziendasicilianatrasporti.it
Bus from Palermo to Vicari
- Ave. Duration
- 1h 35m
- Frequency
- Every 3 hours
- Schedules at
- aziendasicilianatrasporti.it
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Prague to Munich central bus station
- Ave. Duration
- 5h 30m
- Frequency
- Every 4 hours
- Estimated price
- €30–50
- Website
- Flixbus
Bus from Praha, Hlavní Nádraží to Roma, Autostazione Tiburtina
- Ave. Duration
- 21h
- Frequency
- Once daily
- Estimated price
- €120–190
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Palermo
- Ave. Duration
- 13h 55m
- Frequency
- 5 times a week
- Estimated price
- €90–140
- Website
- Flixbus
- Phone
- +420 222 222 221
- [email protected]
- Website
- RegioJet
Bus from Prague to Munich central bus station
- Ave. Duration
- 4h 45m
- Frequency
- 5 times a day
- Estimated price
- €22–40
- Website
- RegioJet
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from München Hackerbrücke to Palermo Piazza Cairoli
- Ave. Duration
- 27h 6m
- Frequency
- Once a week
- Estimated price
- €230–320
- Website
- Onebus
- Phone
- (+39) 0923 98.11.20
- Website
- Autoservizi Salemi Srl
Bus from Trapani Birgi Airport to Palermo Terminal Bus
- Ave. Duration
- 1h 55m
- Frequency
- 6 times a week
- Estimated price
- €6–10
- Schedules at
- Autoservizi Salemi Srl
- Phone
- 090774409
- [email protected]
- Website
- bluferries.it
Car ferry from Villa S. Giovanni to Tresmestieri
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- €19–35
- Schedules at
- bluferries.it
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Booking & Getting There
Prague to Palermo (Region) bus services, operated by FlixBus, arrive at Munich central bus station.
Prague to Palermo (Region) train services, operated by České dráhy (ČD), arrive at Wien Hbf station.
There are 974+ hotels available in Palermo (Region).










































