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How to get fromPrague to Palermo (Region)by plane, bus, train (Trenitalia), car, car ferry, or train

Find Transport to Palermo (Region)

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There are 7 ways to get from Prague to Palermo (Region) by plane, bus, train (Trenitalia), car, car ferry, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Palermo Airport, bus

    best
    1. Fly from Václav Havel Airport Prague (PRG) to Palermo Airport (PMO)plane plane PRG - PMO
    2. Take the bus from Palermo to Vicaribus bus
    8h 15m

  2. Fly to Catania–Fontanarossa Airport, train

    cheapest
    1. Fly from Václav Havel Airport Prague (PRG) to Catania–Fontanarossa Airport (CTA)plane plane PRG - CTA
    2. Take the train from Catania Aeroporto Fontanarossa to Roccapalumba-Aliatrain train
    8h 24m
    €106–247

  3. Train

    1. Take the train from Praha Hlavni Nadrazi to Wien Hbftrain train Rj
    2. Take the train from Wien Hbf to Treviso Centraletrain train Rjx
    3. Take the train from Treviso C.le to Roma Terminitrain train
    4. Take the train from Roma Termini to Termini Imeresetrain train Ic
    30h 27m
    €289–520

  4. Bus

    1. Take the bus from Praha, Hlavní Nádraží to Munich central bus stationbus bus 263 / ...
    2. Take the bus from München Hackerbrücke to Palermo Piazza Cairolibus bus
    3. Take the bus from Palermo to Vicaribus bus
    35h 31m

  5. Drive, car ferry

    1. Drive from Prague to Villa S. Giovannicar car
    2. Take the carferry from Villa S. Giovanni to Tresmestiericarferry car ferry
    3. Drive from Tresmestieri to Palermo (Region)car car
    21h 57m
    €399–586

  6. Fly to Trapani Airport, bus

    1. Fly from Václav Havel Airport Prague (PRG) to Trapani Airport (TPS)plane plane PRG - TPS
    2. Take the bus from Trapani Birgi Airport to Palermo Terminal Busbus bus
    3. Take the bus from Palermo to Vicaribus bus
    12h 2m

  7. Bus via Rome

    1. Take the bus from Prague Florenc Central Bus Station to Rome Tiburtina Bus Stationbus bus
    2. Take the bus from Roma, Autostazione Tiburtina to Palermo Terminal Busbus bus
    3. Take the bus from Palermo to Vicaribus bus
    35h 35m

Václav Havel Airport Prague (PRG) to Palermo Airport (PMO) flights

Calendar11Weekly Planes
Duration3h 18mAverage Duration
Ticket€64Cheapest Price
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Comparing Your Travel Options

Map of how to get from Prague to Palermo (Region).ExpandLaunch map view
  • Distance: 1,430.4 km
  • Duration: 8h 15m

What companies run services between Prague, Czechia and Palermo (Region), Sicily, Italy?

You can take a train from Praha Hlavni Nadrazi to Palermo (Region) via Wien Hbf, Treviso Centrale, Treviso C.le, Roma Termini, Termini Imerese, and Roccapalumba-Alia in around 30h 27m. Alternatively, you can take a bus from Praha, Hlavní Nádraží to Vicari via Munich central bus station, München Hackerbrücke, Palermo Piazza Cairoli, and Palermo in around 35h 31m.

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