There are 9 ways to get from Prague to Sicily by plane, train (Trenitalia), bus, car, car ferry, train, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Catania–Fontanarossa Airport
best- Fly from Václav Havel Airport Prague (PRG) to Catania–Fontanarossa Airport (CTA)plane PRG - CTA
5h 4m€61–168Train
- Take the train from Praha Hlavni Nadrazi to Wien Hbftrain Rj
- Take the train from Wien Hbf to Udinetrain Rjx
- Take the train from Udine to Roma Terminitrain Fr
- Take the train from Roma Termini to Palermo Centraletrain Ic
30h 11m€284–581Bus via Rome
- Take the bus from Prague Florenc Central Bus Station to Rome Tiburtina Bus Stationbus : Prague Central Bus Station - Rome Tiburtina Bus Station / ...
- Take the bus from Roma, Autostazione Tiburtina to Palermo Terminal Busbus Autoservizi Salemi S201
33h 31m€137–199Drive, car ferry
- Drive from Prague to Civitavecchia Portcar
- Take the carferry from Civitavecchia Port to Palermo Portocarferry
26h 34m€249–364Fly to Palermo Airport
- Fly from Václav Havel Airport Prague (PRG) to Palermo Airport (PMO)plane PRG - PMO
5h 35m€65–210Fly to Trapani Airport
- Fly from Václav Havel Airport Prague (PRG) to Trapani Airport (TPS)plane PRG - TPS
9h 17m€70–277Fly to Vincenzo Magliocco Airport
- Fly from Václav Havel Airport Prague (PRG) to Vincenzo Magliocco Airport (CIY)plane PRG - CIY
9h 47m€153–240Train, night train
- Take the train from Praha Hlavni Nadrazi to Linz/Donau Hbftrain Ec
- Take the nighttrain from Linz/Donau Hbf to Venezia S. Lucianighttrain Nj
- Take the train from Venezia S. Lucia to Roma Terminitrain Fr
- Take the train from Roma Termini to Palermo Centraletrain Ic
31h 34m€236–568Bus
- Take the bus from Prague to Munich central bus stationbus FlixBus 183 / ...
- Take the bus from München Hackerbrücke to Palermo Piazza Cairolibus
34h 9m€259–365
Prague to Sicily by train
Questions & Answers
The cheapest way to get from Prague to Sicily is to fly which costs €60 - €170 and takes 5h 4m.
The fastest way to get from Prague to Sicily is to fly which takes 5h 4m and costs €60 - €170.
No, there is no direct bus from Prague station to Sicily. However, there are services departing from Prague Florenc Central Bus Station and arriving at Piazza Boiardo via Roma, Autostazione Tiburtina and Stazione Centrale Pensilina Esterna. The journey, including transfers, takes approximately 33h 31m.
No, there is no direct train from Prague to Sicily. However, there are services departing from Praha Hlavni Nadrazi and arriving at Palermo Notarbartolo via Wien Hbf, Udine, Roma Termini and Palermo Centrale. The journey, including transfers, takes approximately 30h 11m.
The distance between Prague and Sicily is 1425 km.
The best way to get from Prague to Sicily without a car is to train which takes 30h 11m and costs €280 - €600.
It takes approximately 5h 4m to get from Prague to Sicily, including transfers.
Prague to Sicily bus services, operated by RegioJet, depart from Prague Florenc Central Bus Station.
Prague to Sicily train services, operated by České dráhy (ČD), depart from Praha Hlavni Nadrazi station.
The best way to get from Prague to Sicily is to fly which takes 5h 4m and costs €60 - €170. Alternatively, you can train, which costs €280 - €600 and takes 30h 11m, you could also bus via Rome, which costs €130 - €200 and takes 33h 31m.
What companies run services between Prague, Czechia and Sicily, Italy?
Ryanair, Ulendo Airlink, and three other airlines fly from Václav Havel Airport Prague (PRG) to Catania–Fontanarossa Airport (CTA) 3 times a day. Alternatively, you can take a train from Praha Hlavni Nadrazi to Palermo Notarbartolo via Wien Hbf, Udine, Roma Termini, and Palermo Centrale in around 30h 11m.
- Website
- ryanair.com
Flights from Václav Havel Airport Prague to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 20m
- When
- Monday and Friday
- Estimated price
- €55–160
Flights from Václav Havel Airport Prague to Palermo Airport
- Ave. Duration
- 2h 15m
- When
- Tuesday and Saturday
- Estimated price
- €60–190
Flights from Václav Havel Airport Prague to Trapani Airport via Milan Bergamo
- Ave. Duration
- 5h 50m
- When
- Sunday and Thursday
- Estimated price
- €65–280
Flights from Václav Havel Airport Prague to Trapani Airport via Bologna
- Ave. Duration
- 7h 5m
- When
- Tuesday and Friday
- Estimated price
- €65–270
Flights from Václav Havel Airport Prague to Trapani Airport via Bari
- Ave. Duration
- 10h 45m
- When
- Monday
- Estimated price
- €65–280
Flights from Václav Havel Airport Prague to Trapani Airport via Rome
- Ave. Duration
- 6h 25m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- €95–290
- Phone
- +420 221 111 122
- [email protected]
- Website
- Czech Railways (ČD)
Train from Praha Hlavni Nadrazi to Wien Hbf
- Ave. Duration
- 4h 12m
- Frequency
- Hourly
- Estimated price
- €45–70
- Website
- Czech Railways (ČD)
Train from Praha Hlavni Nadrazi to Linz/Donau Hbf
- Ave. Duration
- 5h 53m
- Frequency
- Twice daily
- Estimated price
- €30–50
- Website
- Czech Railways (ČD)
- Phone
- +420 222 222 221
- [email protected]
- Website
- RegioJet
Bus from Prague Florenc Central Bus Station to Rome Tiburtina Bus Station
- Ave. Duration
- 20h 15m
- Frequency
- Once a week
- Estimated price
- €100–150
- Website
- RegioJet
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Civitavecchia Port to Palermo Porto
- Ave. Duration
- 13h 15m
- Frequency
- Once a week
- Estimated price
- €60–90
- Website
- Grandi Navi Veloci
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
More Questions & Answers
Prague to Sicily bus services, operated by RegioJet, arrive at Rome Tiburtina Bus Station.
Prague to Sicily train services, operated by České dráhy (ČD), arrive at Wien Hbf station.
There are 6308+ hotels available in Sicily.











