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How to get fromPrairie du Chien to Chicagoby car, plane, bus, or train

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There are 7 ways to get from Prairie du Chien to Chicago by car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to La Crosse, fly

    best
    1. Drive from Prairie du Chien to La-Crosse-Airport-LSEcar car
    2. Fly from La Crosse (LSE) to Chicago O'Hare International Airport (ORD)plane plane LSE - ORD
    3h 35m
    $49–272

  2. Drive 225.7 mi

    cheapest
    1. Drive from Prairie du Chien to Chicagocar car 225.7 mi
    4h 44m
    $42–60

  3. Drive, bus, train

    1. Drive from Prairie du Chien to La Crossecar car
    2. Take the bus from La Crosse to Milwaukeebus bus
    3. Take the train from Milwaukee to Chicago Union Stationtrain train
    7h 35m
    $86–146

  4. Drive to The Eastern Iowa Airport, fly

    1. Drive from Prairie du Chien to Cedar-Rapids-Airport-CIDcar car
    2. Fly from The Eastern Iowa Airport (CID) to Chicago O'Hare International Airport (ORD)plane plane CID - ORD
    4h 16m
    $56–283

  5. Drive to Waterloo Municipal Airport, fly

    1. Drive from Prairie du Chien to Waterloo Municipal Airport (ALO)car car
    2. Fly from Waterloo Municipal Airport (ALO) to Chicago O'Hare International Airport (ORD)plane plane ALO - ORD
    4h 10m
    $54–289

  6. Drive, bus

    1. Drive from Prairie du Chien to La Crossecar car
    2. Take the bus from La Crosse to Madisonbus bus
    3. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    8h 14m
    $72–131

  7. Drive, bus via Chicago Bus Station

    1. Drive from Prairie du Chien to La Crossecar car
    2. Take the bus from La Crosse to Madisonbus bus
    3. Take the bus from Madison to Chicago Bus Stationbus bus
    8h 46m
    $71–121

La Crosse (LSE) to Chicago O'Hare International Airport (ORD) flights

Calendar28Weekly Planes
Duration1h 24mAverage Duration
Ticket$35Cheapest Price
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Questions & Answers

Map of how to get from Prairie du Chien to Chicago.ExpandLaunch map view
  • Distance: 297.2 mi
  • Duration: 3h 35m

What companies run services between Prairie du Chien, WI, USA and Chicago, IL, USA?

There is no direct connection from Prairie du Chien to Chicago. However, you can drive to La-Crosse-Airport-LSE airport, fly to Chicago O'Hare International Airport (ORD), walk to O'Hare, then take the subway to Jackson-Blue. Alternatively, you can take a vehicle from Prairie du Chien to Chicago Union Station via La Crosse, Milwaukee, and Milwaukee in around 7h 35m.

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