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How to get fromPrairie du Chien to St. Louisby car, plane, bus, or train

Find Transport to St. Louis

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There are 6 ways to get from Prairie du Chien to St. Louis by car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to La Crosse, fly

    best
    1. Drive from Prairie du Chien to La-Crosse-Airport-LSEcar car
    2. Fly from La Crosse (LSE) to Lambert–St. Louis International Airport (STL)plane plane LSE - STL
    6h 38m
    $95–490

  2. Drive 378.3 mi

    cheapest
    1. Drive from Prairie du Chien to St. Louiscar car 378.3 mi
    7h 4m
    $69–100

  3. Drive, bus, train via Milwaukee

    1. Drive from Prairie du Chien to La Crossecar car
    2. Take the bus from La Crosse to Milwaukeebus bus
    3. Take the train from Milwaukee to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to St. Louistrain train
    13h 21m
    $159–316

  4. Drive, bus, train

    1. Drive from Prairie du Chien to La Crossecar car
    2. Take the bus from La Crosse to Madisonbus bus
    3. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    4. Take the train from Chicago Union Station to St. Louistrain train
    14h
    $147–301

  5. Drive, bus to Minneapolis–Saint Paul International Airport, fly

    1. Drive from Prairie du Chien to La Crossecar car
    2. Take the bus from La Crosse to St. Paulbus bus
    3. Fly from Minneapolis–Saint Paul International Airport (MSP) to Lambert–St. Louis International Airport (STL)plane plane MSP - STL
    8h 31m
    $436–1,037

  6. Drive, bus

    1. Drive from Prairie du Chien to La Crossecar car
    2. Take the bus from La Crosse to Milwaukeebus bus
    3. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    4. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    14h 36m
    $113–190

La Crosse (LSE) to Lambert–St. Louis International Airport (STL) flights

Calendar28Weekly Planes
Duration5h 12mAverage Duration
Ticket$81Cheapest Price
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Questions & Answers

Map of how to get from Prairie du Chien to St. Louis.ExpandLaunch map view
  • Distance: 436.3 mi
  • Duration: 6h 38m

What companies run services between Prairie du Chien, WI, USA and St. Louis, MO, USA?

There is no direct connection from Prairie du Chien to St. Louis. However, you can drive to La-Crosse-Airport-LSE airport, fly to Lambert–St. Louis International Airport (STL), walk to LAMBERT AIRPORT TERMINAL #1 station, then take the train to CIVIC CENTER station. Alternatively, you can take a vehicle from Prairie du Chien to St. Louis via La Crosse, Milwaukee, Milwaukee, and Chicago Union Station in around 13h 21m.

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