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How to get fromPrescott to La Crosseby train (Amtrak), bus, car, or train

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There are 4 ways to get from Prescott to La Crosse by train (Amtrak), bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train Empire Builder / ...
    3h 12m
    $103–160
  2. Drive 114 mi

    cheapest
    1. Drive from Prescott to La Crossecar car 114 mi
    2h 20m
    $21–31
  3. Bus

    1. Take the bus from St. Paul to La Crossebus bus Jefferson Lines 965
    5h 36m
    $98–135
  4. Line 68 bus, train

    1. Take the bus from 75th St E & Dawn Ave to Robert St & Kellogg Blvdbus bus 68 / ...
    2. Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain train Empire Builder / ...
    5h 3m
    $98–155

Questions & Answers

What companies run services between Prescott, WI, USA and La Crosse, WI, USA?

Amtrak operates a train from St. Paul-Minneapolis to La Crosse Amtrak Station 3 times a day. Tickets cost $40–85 and the journey takes 2h 47m. Alternatively, Jefferson Lines operates a bus from St. Paul to La Crosse once daily. Tickets cost $40–65 and the journey takes 3h 20m.

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Bus operators

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