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How to get fromPresque Isle to Chicagoby plane, bus (Amtrak, Flixbus), bus, train, car, or bus (Amtrak, Greyhound)

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There are 7 ways to get from Presque Isle to Chicago by plane, bus (Amtrak, Flixbus), bus, train, car, or bus (Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Presque Isle to Chicago O'Hare International Airport

    best
    1. Fly from Presque Isle (PQI) to Chicago O'Hare International Airport (ORD)plane plane PQI - ORD
    6h 34m
    $99–434

  2. Bus

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus bus
    3. Take the bus from Boston to New York Midtownbus bus
    4. Take the bus from New York Midtown to Chicago Bus Stationbus bus
    31h 58m
    $215–351

  3. Bus, train

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus bus
    3. Take the train from Boston to Chicago Union Stationtrain train
    32h 12m
    $336–701

  4. Drive 1,219.3 mi

    1. Drive from Presque Isle to Chicagocar car 1,219.3 mi
    22h 21m
    $223–322

  5. Fly Presque Isle to General Mitchell International Airport, train

    1. Fly from Presque Isle (PQI) to General Mitchell International Airport (MKE)plane plane PQI - MKE
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    8h 54m
    $181–773

  6. Bus to Bangor, fly to Chicago O'Hare International Airport

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Fly from Bangor (BGR) to Chicago O'Hare International Airport (ORD)plane plane BGR - ORD
    8h 46m
    $105–418

  7. Bus via Brook Park

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus bus
    3. Take the bus from Boston to Cleveland Bus Stationbus bus
    4. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus
    32h 5m
    $206–376

Presque Isle to Chicago by bus

Calendar7Weekly Buses
Duration31h 58mAverage Duration
Ticket$215Cheapest Price
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Questions & Answers

Map of how to get from Presque Isle to Chicago.ExpandLaunch map view
  • Distance: 1,050.7 mi
  • Duration: 6h 34m

What companies run services between Presque Isle, ME, USA and Chicago, IL, USA?

JetBlue Airways and American Airlines fly from Presque Isle (PQI) to Chicago O'Hare International Airport (ORD) twice daily. Alternatively, you can take a bus from Presque Isle, Maine to Chicago Bus Station via Bangor, ME, Bangor Transportation Center, Boston, MA - South Station, Boston, and New York Midtown in around 31h 58m.

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