Rome2Rio

How to get fromPresque Isle to Fort Myersby plane, bus (Amtrak, Greyhound, Flixbus), bus, train, or car

Find Transport to Fort Myers

See all options

There are 8 ways to get from Presque Isle to Fort Myers by plane, bus (Amtrak, Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Ft. Myers

    best
    1. Fly from Presque Isle (PQI) to Ft. Myers (RSW)plane plane PQI - RSW
    10h 46m
    $150–664

  2. Fly to Sarasota–Bradenton International Airport, bus

    cheapest
    1. Fly from Presque Isle (PQI) to Sarasota–Bradenton International Airport (SRQ)plane plane PQI - SRQ
    2. Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stopbus bus
    11h 21m
    $140–580

  3. Bus

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus bus
    3. Take the bus from Boston to Newark Penn Stationbus bus
    4. Take the bus from Newark Penn Station to Orlando Bus Stationbus bus
    5. Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus bus
    42h 3m
    $311–486

  4. Bus, train via Washington

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus bus
    3. Take the train from Boston to Washington Union Stationtrain train
    4. Take the train from Washington Union Station to Tampatrain train
    5. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    43h 54m
    $889–1,425

  5. Drive  1,814.4 mi

    1. Drive from Presque Isle to Fort Myerscar car 1,814.4 mi
    31h 45m
    $311–448

  6. Fly to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from Presque Isle (PQI) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane PQI - FLL
    2. Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus bus
    12h 7m
    $159–644

  7. Fly to Tampa, bus

    1. Fly from Presque Isle (PQI) to Tampa (TPA)plane plane PQI - TPA
    2. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    13h 11m
    $158–691

  8. Bus, train

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus bus
    3. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the train from Ny Moynihan Train Hall At Penn Station to Kissimmee Amtrak Stationtrain train
    5. Take the bus from Orlando to Fort Myers Bus Stopbus bus
    44h 38m
    $753–1,908

Presque Isle to Fort Myers by bus

Calendar7Weekly Buses
Duration42h 3mAverage Duration
Ticket$311Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Presque Isle to Fort Myers.ExpandLaunch map view
  • Distance: 1,598.6 mi
  • Duration: 10h 46m

What companies run services between Presque Isle, ME, USA and Fort Myers, FL, USA?

JetBlue Airways flies from Presque Isle (PQI) to Ft. Myers (RSW) twice daily. Alternatively, you can take a bus from Presque Isle, Maine to Fort Myers Bus Stop via Bangor, ME, Bangor Transportation Center, Boston, MA - South Station, Boston, Newark Penn Station, and Orlando Bus Station in around 42h 3m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There