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How to get fromPresque Isle to Syracuseby plane, bus (Amtrak, Greyhound, Flixbus), bus, train, car, or bus (Amtrak, Flixbus)

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There are 9 ways to get from Presque Isle to Syracuse by plane, bus (Amtrak, Greyhound, Flixbus), bus, train, car, or bus (Amtrak, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Presque Isle to Syracuse Hancock International Airport

    best
    1. Fly from Presque Isle (PQI) to Syracuse Hancock International Airport (SYR)plane plane PQI - SYR
    5h 29m
    $128–717

  2. Bus

    cheapest
    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus bus
    3. Take the bus from Boston to Syracuse Bus Stationbus bus
    16h 15m
    $111–196

  3. Bus, train

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Take the bus from Bangor Transportation Center to Boston, MA - South Stationbus bus
    3. Take the train from Boston to Syracuse Regional Transportation Centertrain train
    18h 51m
    $176–331

  4. Drive 622.9 mi

    1. Drive from Presque Isle to Syracusecar car 622.9 mi
    12h 39m
    $114–165

  5. Fly Presque Isle to Rochester, train

    1. Fly from Presque Isle (PQI) to Rochester (ROC)plane plane PQI - ROC
    2. Take the train from Rochester to Syracuse Regional Transportation Centertrain train
    8h 15m
    $166–851

  6. Bus to Bangor, fly to Syracuse Hancock International Airport

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Fly from Bangor (BGR) to Syracuse Hancock International Airport (SYR)plane plane BGR - SYR
    10h 56m
    $219–1,141

  7. Drive to Fredericton International Airport, fly to Ottawa Macdonald-Cartier International Airport, bus

    1. Drive from Presque Isle to Fredericton-Airport-YFCcar car
    2. Fly from Fredericton International Airport (YFC) to Ottawa Macdonald-Cartier International Airport (YOW)plane plane YFC - YOW
    3. Take the bus from Ottawa to Syracuse Bus Stationbus bus
    10h 5m
    $220–492

  8. Fly Presque Isle to Boston Logan Airport, train

    1. Fly from Presque Isle (PQI) to Boston Logan Airport (BOS)plane plane PQI - BOS
    2. Take the train from Boston to Syracuse Regional Transportation Centertrain train
    11h 46m
    $171–548

  9. Bus via West Albany

    1. Take the bus from Presque Isle, Maine to Bangor, MEbus bus
    2. Take the bus from Bangor Transportation Center to Augusta Transportation Centerbus bus
    3. Take the bus from Augusta to Springfield Union Stationbus bus
    4. Take the bus from Springfield Union Station to Albanybus bus
    5. Take the bus from Albany to Syracusebus bus
    18h 36m
    $118–209

Presque Isle to Syracuse by bus

Calendar7Weekly Buses
Duration16h 15mAverage Duration
Ticket$111Cheapest Price
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Questions & Answers

Map of how to get from Presque Isle to Syracuse.ExpandLaunch map view
  • Distance: 479.3 mi
  • Duration: 5h 29m

What companies run services between Presque Isle, ME, USA and Syracuse, NY, USA?

JetBlue Airways, American Airlines, and Delta fly from Presque Isle (PQI) to Syracuse Hancock International Airport (SYR) twice daily. Alternatively, you can take a bus from Presque Isle, Maine to Syracuse Bus Station via Bangor, ME, Bangor Transportation Center, Boston, MA - South Station, and Boston in around 16h 15m.

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