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How to get fromPrinceton to Mayo Clinicby train, plane, bus, or car

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There are 8 ways to get from Princeton to Mayo Clinic by train, plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago O'Hare International Airport, fly to Rochester

    best
    1. Take the train from Princeton Station to La Grange Amtraktrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane plane ORD - RST
    6h 36m
    $74–397

  2. Drive 297.6 mi

    cheapest
    1. Drive from Princeton to Mayo Cliniccar car 297.6 mi
    5h 58m
    $55–79

  3. Train, bus via Madison

    1. Take the train from Princeton Station to La Grange Amtraktrain train
    2. Take the bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    11h 58m
    $104–188

  4. Train, bus

    1. Take the train from Princeton Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochesterbus bus
    13h 25m
    $191–378

  5. Train to Chicago O'Hare International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from Princeton Station to La Grange Amtraktrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Minneapolis–Saint Paul International Airport (MSP)plane plane ORD - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 19m
    $305–569

  6. Train to Chicago Midway International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from Princeton Station to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Minneapolis–Saint Paul International Airport (MSP)plane plane MDW - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    8h 37m
    $165–608

  7. Train, bus #2

    1. Take the train from Princeton Station to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    12h 27m
    $108–198

  8. Train, bus #3

    1. Take the train from Princeton Station to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to Madisonbus bus
    3. Take the bus from Madison to Rochesterbus bus
    12h 43m
    $109–193

Princeton to Mayo Clinic by train, bus, and foot

Calendar7Weekly Services
Duration11h 58mAverage Duration
Ticket$104Cheapest Price
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Questions & Answers

Map of how to get from Princeton to Mayo Clinic.ExpandLaunch map view
  • Distance: 383.3 mi
  • Duration: 6h 36m

What companies run services between Princeton, IL, USA and Mayo Clinic, MN, USA?

There is no direct connection from Princeton to Mayo Clinic. However, you can take the train to La Grange Amtrak, walk to La Grange/Burlington Ave., take the line 330 bus to Rosemont CTA Station, walk to Rosemont, take the subway to O'Hare, walk to Chicago O'Hare International Airport (ORD) airport, fly to Rochester (RST), walk to Rochester - Airport, take the shuttle to Rochester, then walk to Mayo Clinic. Alternatively, you can take a train from Princeton Station to Mayo Clinic via La Grange Amtrak, La Grange/Burlington Ave., Multi-Modal/Rental Car Facility, 250 N. Lake St - Madison UW Campus, Madison, and Rochester in around 11h 58m.

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