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How to get fromPtolemaḯda to Istanbulby bus, car, or plane

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There are 6 ways to get from Ptolemaḯda to Istanbul by bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Alexandroupoli

    best
    1. Take the bus from Ptolemaida to Thessaloniki Macedonia KTEL Bus Stationbus bus
    2. Take the bus from Thessaloniki Macedonia KTEL Bus Station to Alexandroupolibus bus
    3. Take the bus from Alexandroupoli Evros Bus Station to Istanbul Esenler Otogaribus bus
    11h
  2. Drive  726.3 km

    cheapest
    1. Drive from Ptolemaḯda to Istanbulcar car 726.3 km
    7h 43m
    ₺7,807–11,276
  3. Bus, fly

    1. Take the bus from Ptolemaida to Thessaloniki Macedonia KTEL Bus Stationbus bus
    2. Fly from Thessaloniki Airport Makedonia (SKG) to Istanbul Airport (IST)plane plane SKG - IST
    7h 35m
  4. Bus

    1. Take the bus from Ptolemaida to Thessaloniki Macedonia KTEL Bus Stationbus bus
    2. Take the bus from Thessaloniki Macedonia KTEL Bus Station to Istanbul Esenler Otogaribus bus Arda-Tur
    11h 1m
  5. Bus via Komotini

    1. Take the bus from Ptolemaida to Thessaloniki Macedonia KTEL Bus Stationbus bus
    2. Take the bus from Thessaloniki Macedonia KTEL Bus Station to Komotinibus bus
    3. Take the bus from Komotini to Istanbul Otogaribus bus
    14h 45m
  6. Bus #2

    1. Take the bus from Ptolemaida to Thessaloniki Macedonia KTEL Bus Stationbus bus
    2. Take the bus from Thessaloniki Macedonia KTEL Bus Station to Istanbulbus bus
    15h

Thessaloniki Airport Makedonia (SKG) to Istanbul Airport (IST) flights

Calendar50Weekly Planes
Duration2h 52mAverage Duration
Ticket₺4,769Cheapest Price
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Comparing Your Travel Options

What companies run services between Ptolemaḯda, Greece and Istanbul, Turkey?

You can take a bus from Ptolemaida to Istanbul Esenler Otogari via Thessaloniki Macedonia KTEL Bus Station and Alexandroupoli Evros Bus Station in around 11h.

Airlines
Bus operators

Want to know more about travelling around the world?

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