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How to get fromPuebla to Panama Cityby bus, plane, or car

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There are 5 ways to get from Puebla to Panama City by bus, plane, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Benito Juárez International Airport, fly

    best
    1. Take the bus from Puebla Terminal CAPU to Terminal Central de Autobuses del Nortebus bus
    2. Fly from Benito Juárez International Airport (MEX) to Tocumen International Airport (PTY)plane plane MEX - PTY
    8h 37m
    $346–613

  2. Bus

    cheapest
    1. Take the bus from Puebla to Tapachulabus bus
    2. Take the bus from Tapachula to Guatemana Aguilar Batresbus bus
    3. Take the bus from Guatemala Aguilar Batres to Terminal San Carlos - Ticabusbus bus
    4. Take the bus from Terminal Tica Bus San Salvador to Terminal Tica Bus San Josébus bus
    5. Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus bus
    2d 19h
    $198–284

  3. Drive  3,032.3 km

    1. Drive from Puebla to Panama Citycar car 3,032.3 km
    43h 27m
    $415–600

  4. Fly from Hermanos Serdán International Airport

    1. Fly from Hermanos Serdán International Airport (PBC) to Tocumen International Airport (PTY)plane plane PBC - PTY
    9h 24m
    $201–743

  5. Bus to Felipe Ángeles International Airport, fly

    1. Take the bus from Puebla Terminal CAPU to Terminal Central de Autobuses del Nortebus bus
    2. Fly from Felipe Ángeles International Airport (NLU) to Tocumen International Airport (PTY)plane plane NLU - PTY
    12h 45m
    $607–1,373

Benito Juárez International Airport (MEX) to Tocumen International Airport (PTY) flights

Calendar60Weekly Planes
Duration4h 14mAverage Duration
Ticket$106Cheapest Price
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Comparing Your Travel Options

Map of how to get from Puebla to Panama City.ExpandLaunch map view
  • Distance: 2,577.1 km
  • Duration: 8h 37m

What companies run services between Puebla, Mexico and Panama City, Panama?

You can take a bus from Puebla to Terminal Tica Bus Panamá via Tapachula, Guatemala Aguilar Batres, Terminal San Carlos - Ticabus, Terminal Tica Bus San Salvador, and Terminal Tica Bus San José in around 2d 19h. Alternatively, Volaris, Copa Airlines, and Viva Aerobus fly from Hermanos Serdán International Airport (PBC) to Tocumen International Airport (PTY) twice daily.

Airlines
Bus operators

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