There are 6 ways to get from Pueblo to Des Moines by bus, plane, bus (Greyhound, Flixbus), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Colorado Springs Airport, fly
best- Take the bus from Pueblo, CO to Colorado Springs, CObus
- Fly from Colorado Springs Airport (COS) to Des Moines (DSM)plane COS - DSM
6h 49m$156–660Bus
cheapest- Take the bus from Pueblo Transit to Denver Union Stationbus Greyhound US1144 / ...
- Take the bus from Denver Union Station to Des Moinesbus Greyhound US0123S
16h 25m$111–220Drive 734.4 mi
- Drive from Pueblo to Des Moinescar 734.4 mi
12h 34m$134–194Bus to Denver, fly
- Take the bus from Pueblo Transit to Denver Union Stationbus
- Fly from Denver (DEN) to Des Moines (DSM)plane DEN - DSM
6h 7m$143–611Fly from Pueblo Memorial Airport
- Fly from Pueblo Memorial Airport (PUB) to Des Moines (DSM)plane PUB - DSM
4h 11m$175–728Bus via Omaha
- Take the bus from Pueblo, CO to Denverbus
- Take the bus from Denver to Omaha, NEbus
- Take the bus from Omaha, NE to Des Moinesbus
16h 49m$221–284
Pueblo to Des Moines by bus
Questions & Answers
The cheapest way to get from Pueblo to Des Moines is to bus which costs $110 - $220 and takes 16h 25m.
The fastest way to get from Pueblo to Des Moines is to fly which takes 4h 11m and costs $170 - $750.
No, there is no direct bus from Pueblo to Des Moines. However, there are services departing from Pueblo Transit and arriving at Des Moines via Denver Union Station. The journey, including transfers, takes approximately 16h 25m.
The distance between Pueblo and Des Moines is 677 miles. The road distance is 738.7 miles.
The best way to get from Pueblo to Des Moines without a car is to bus which takes 16h 25m and costs $110 - $220.
It takes approximately 6h 49m to get from Pueblo to Des Moines, including transfers.
Pueblo to Des Moines bus services, operated by Greyhound USA, depart from Pueblo Transit station.
The best way to get from Pueblo to Des Moines is to bus which takes 16h 25m and costs $110 - $220. Alternatively, you can fly, which costs $170 - $750 and takes 4h 11m.
Pueblo to Des Moines bus services, operated by Greyhound USA, arrive at Denver Union Station.
Des Moines is 1h ahead of Pueblo. It is currently 11:20 AM in Pueblo and 12:20 PM in Des Moines.
What companies run services between Pueblo, CO, USA and Des Moines, IA, USA?
You can take a bus from Pueblo Transit to Des Moines via Denver Union Station in around 16h 25m. Alternatively, Key Lime and United Airlines fly from Pueblo Memorial Airport (PUB) to Des Moines (DSM) twice daily.
- Website
- united.com
Flights from Colorado Springs Airport to Des Moines via Denver
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $110–600
Flights from Colorado Springs Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 6h 5m
- When
- Every day
- Estimated price
- $160–800
Flights from Denver to Des Moines
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $100–550
Flights from Pueblo Memorial Airport to Des Moines via Denver
- Ave. Duration
- 3h 39m
- When
- Every day
- Estimated price
- $110–650
- Phone
- +1 866 691 9732
- [email protected]
- Website
- Limousine Express
Bus from Pueblo, CO to Colorado Springs, CO
- Ave. Duration
- 45 min
- Frequency
- Twice daily
- Estimated price
- $25–40
- Website
- Limousine Express
- One Way
- $25–40
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More Questions & Answers
Yes, the driving distance between Pueblo to Des Moines is 739 miles. It takes approximately 12h 34m to drive from Pueblo to Des Moines.
Book your Pueblo to Des Moines bus tickets online with Omio and FlixBus.
There are 267+ hotels available in Des Moines.




