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How to get fromPueblo to Des Moinesby bus, plane, bus (Greyhound, Flixbus), car, or bus (Greyhound)

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There are 6 ways to get from Pueblo to Des Moines by bus, plane, bus (Greyhound, Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Colorado Springs Airport, fly

    best
    1. Take the bus from Pueblo, CO to Colorado Springs, CObus bus
    2. Fly from Colorado Springs Airport (COS) to Des Moines (DSM)plane plane COS - DSM
    6h 53m
    $166–710

  2. Bus

    cheapest
    1. Take the bus from Pueblo Transit to Denver Union Stationbus bus Greyhound US1144 / ...
    2. Take the bus from Denver Union Station to Des Moinesbus bus Greyhound US0123S
    16h 25m
    $128–245

  3. Drive 734.4 mi

    1. Drive from Pueblo to Des Moinescar car 734.4 mi
    12h 34m
    $134–194

  4. Bus to Denver, fly

    1. Take the bus from Pueblo Transit to Denver Union Stationbus bus
    2. Fly from Denver (DEN) to Des Moines (DSM)plane plane DEN - DSM
    6h 7m
    $155–666

  5. Fly from Pueblo Memorial Airport

    1. Fly from Pueblo Memorial Airport (PUB) to Des Moines (DSM)plane plane PUB - DSM
    4h 11m
    $185–728

  6. Bus via Omaha

    1. Take the bus from Pueblo, CO to Denverbus bus
    2. Take the bus from Denver to Omaha, NEbus bus
    3. Take the bus from Omaha, NE to Des Moinesbus bus
    16h 49m
    $224–289

Pueblo to Des Moines by bus

Calendar7Weekly Buses
Duration16h 25mAverage Duration
Ticket$128Cheapest Price
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Questions & Answers

Map of how to get from Pueblo to Des Moines.ExpandLaunch map view
  • Distance: 673.4 mi
  • Duration: 6h 53m

What companies run services between Pueblo, CO, USA and Des Moines, IA, USA?

You can take a bus from Pueblo Transit to Des Moines via Denver Union Station in around 16h 25m. Alternatively, Key Lime and United Airlines fly from Pueblo Memorial Airport (PUB) to Des Moines (DSM) twice daily.

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