There are 8 ways to get from Pueblo to Des Moines by bus, plane, bus (Greyhound, Flixbus), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Colorado Springs Airport, fly to Des Moines
best- Take the bus from Pueblo, CO to Colorado Springsbus
- Fly from Colorado Springs Airport (COS) to Des Moines (DSM)plane COS - DSM
7h 10m$133–469Bus to Denver, fly to Fort Dodge Municipal Airport, drive
cheapest- Take the bus from Pueblo Transit to Denver Union Stationbus
- Fly from Denver (DEN) to Fort Dodge Municipal Airport (FOD)plane DEN - FOD
- Drive from Fort Dodge Municipal Airport (FOD) to Des Moinescar
8h$94–404Bus
- Take the bus from Pueblo Transit to Denver Union Stationbus Greyhound US1144 / ...
- Take the bus from Denver Union Station to Des Moinesbus Greyhound US0123S
16h 25m$138–209Drive 734.4 mi
- Drive from Pueblo to Des Moinescar 734.4 mi
12h 34m$134–194Bus to Denver, fly to Des Moines
- Take the bus from Pueblo Transit to Denver Union Stationbus
- Fly from Denver (DEN) to Des Moines (DSM)plane DEN - DSM
6h 2m$96–412Fly Pueblo Memorial Airport to Des Moines
- Fly from Pueblo Memorial Airport (PUB) to Des Moines (DSM)plane PUB - DSM
4h 21m$136–480Drive to San Luis Valley Regional Airport, fly to Des Moines
- Drive from Pueblo to San Luis Valley Regional Airport (ALS)car
- Fly from San Luis Valley Regional Airport (ALS) to Des Moines (DSM)plane ALS - DSM
6h 6m$150–435Bus via Omaha
- Take the bus from Pueblo to Denverbus
- Take the bus from Denver to Omahabus
- Take the bus from Omaha, NE to Des Moinesbus
17h$205–260
Pueblo to Des Moines by bus
Comparing Your Travel Options
The cheapest way to get from Pueblo to Des Moines is to bus which costs $130 - $210 and takes 16h 25m.
The fastest way to get from Pueblo to Des Moines is to fly which takes 4h 21m and costs $130 - $480.
No, there is no direct bus from Pueblo to Des Moines. However, there are services departing from Pueblo Transit and arriving at Des Moines via Denver Union Station. The journey, including transfers, takes approximately 16h 25m.
The distance between Pueblo and Des Moines is 681 miles. The road distance is 738.7 miles.
The best way to get from Pueblo to Des Moines without a car is to bus which takes 16h 25m and costs $130 - $210.
It takes approximately 7h 10m to get from Pueblo to Des Moines, including transfers.
Pueblo to Des Moines bus services, operated by Greyhound USA, depart from Pueblo Transit station.
The best way to get from Pueblo to Des Moines is to bus which takes 16h 25m and costs $130 - $210. Alternatively, you can fly, which costs $130 - $480 and takes 4h 21m.
Pueblo to Des Moines bus services, operated by Greyhound USA, arrive at Denver Union Station.
Des Moines is 1h ahead of Pueblo. It is currently 7:28 AM in Pueblo and 8:28 AM in Des Moines.
What companies run services between Pueblo, CO, USA and Des Moines, IA, USA?
You can take a bus from Pueblo Transit to Des Moines via Denver Union Station in around 16h 25m. Alternatively, Key Lime, United Airlines, and Southwest Airlines fly from Pueblo Memorial Airport (PUB) to Des Moines (DSM) twice daily.
- Website
- united.com
Flights from Colorado Springs Airport to Des Moines via Denver
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $70–390
Flights from Colorado Springs Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 40m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–490
Flights from Denver to Des Moines
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $60–360
Flights from Pueblo Memorial Airport to Des Moines via Denver
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- $70–400
Flights from Denver to Fort Dodge Municipal Airport
- Ave. Duration
- 1h 54m
- When
- Every day
- Estimated price
- $60–350
Flights from San Luis Valley Regional Airport to Des Moines via Denver
- Ave. Duration
- 3h 46m
- When
- Monday, Tuesday, Thursday, Friday, and Saturday
- Estimated price
- $75–410
- Website
- southwest.com
Flights from Colorado Springs Airport to Des Moines via Denver
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $70–390
Flights from Colorado Springs Airport to Des Moines via Chicago Midway
- Ave. Duration
- 8h 10m
- When
- Monday, Thursday, and Friday
- Estimated price
- $100–490
Flights from Denver to Des Moines
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $60–360
Flights from Pueblo Memorial Airport to Des Moines via Denver, Chicago Midway
- Ave. Duration
- 6h 20m
- When
- Thursday and Friday
- Estimated price
- $110–550
Flights from San Luis Valley Regional Airport to Des Moines via Denver, Chicago Midway
- Ave. Duration
- 7h 55m
- When
- Sunday
- Estimated price
- $110–550
- Website
- aa.com
Flights from Colorado Springs Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 6h 11m
- When
- Every day
- Estimated price
- $100–490
Flights from San Luis Valley Regional Airport to Des Moines via Denver, Dallas/Ft.Worth
- Ave. Duration
- 8h 7m
- When
- Every day
- Estimated price
- $110–550
- Website
- flyfrontier.com
Flights from Denver to Des Moines
- Ave. Duration
- 1h 42m
- When
- Monday and Friday
- Estimated price
- $100–350
Flights from San Luis Valley Regional Airport to Des Moines via Denver
- Ave. Duration
- 4h 30m
- When
- Monday and Friday
- Estimated price
- $110–380
- Website
- delta.com
Flights from Colorado Springs Airport to Des Moines via Minneapolis
- Ave. Duration
- 7h 14m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $85–440
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Pueblo, CO to Colorado Springs
- Ave. Duration
- 50 min
- Frequency
- 4 times a day
- Estimated price
- $40–55
- Schedules at
- Omnibus Express
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Pueblo Transit to Denver Union Station
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $20–30
- Website
- Greyhound
Bus from Denver Union Station to Des Moines
- Ave. Duration
- 13h
- Frequency
- Once daily
- Estimated price
- $120–180
- Website
- Greyhound
Bus from Pueblo Transit to Denver Union Station
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $20–30
- Website
- Greyhound
Bus from Pueblo Transit to Denver Union Station
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $20–30
- Website
- Greyhound
Bus from Omaha, NE to Des Moines
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $23–35
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Pueblo Transit to Denver Union Station
- Ave. Duration
- 2h 30m
- Frequency
- 6 times a week
- Estimated price
- $17–27
- Schedules at
- Flixbus USA
Bus from Pueblo Transit to Denver Union Station
- Ave. Duration
- 2h 30m
- Frequency
- 6 times a week
- Estimated price
- $17–27
- Schedules at
- Flixbus USA
Bus from Pueblo Transit to Denver Union Station
- Ave. Duration
- 2h 30m
- Frequency
- 6 times a week
- Estimated price
- $17–27
- Schedules at
- Flixbus USA
- Phone
- +1 866 691 9732
- [email protected]
- Website
- Limousine Express
Bus from Pueblo to Denver
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $30–45
- Website
- Limousine Express
- One Way
- $30–45
- Phone
- +1-877-779-2999
- [email protected]
- Website
- Express Arrow
Bus from Denver to Omaha
- Ave. Duration
- 10h 40m
- Frequency
- Once daily
- Estimated price
- $150–180
- Website
- Express Arrow
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Booking & Getting There
Yes, the driving distance between Pueblo to Des Moines is 739 miles. It takes approximately 12h 34m to drive from Pueblo to Des Moines.
Book your Pueblo to Des Moines bus tickets online with Omio and FlixBus.
There are 255+ hotels available in Des Moines.











