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How to get fromPueblo to Santa Anaby bus, plane, train, bus (Greyhound, Flixbus), or car

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There are 7 ways to get from Pueblo to Santa Ana by bus, plane, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Colorado Springs Airport, fly

    best
    1. Take the bus from Pueblo, CO to Colorado Springs, CObus bus
    2. Fly from Colorado Springs Airport (COS) to John Wayne Airport Orange County (SNA)plane plane COS - SNA
    5h 36m
    $158–564

  2. Bus, train

    1. Take the bus from Pueblo, CO to Las Vegas Transportation Centerbus bus Denver
    2. Take the train from Las Vegas Amtrak Station to Fullerton Amtrak Stationtrain train Southwest Chief
    25h 18m
    $386–784

  3. Bus

    1. Take the bus from Pueblo Transit to Denver Union Stationbus bus
    2. Take the bus from Denver Union Station to Las Vegas Bus Terminalbus bus
    3. Take the bus from Las Vegas Bus Terminal to Santa Ana Bus Stopbus bus
    25h 25m
    $178–344

  4. Drive 1,055.9 mi

    1. Drive from Pueblo to Santa Anacar car 1,055.9 mi
    17h 33m
    $193–279

  5. Bus to Denver, fly

    1. Take the bus from Pueblo Transit to Denver Union Stationbus bus
    2. Fly from Denver (DEN) to John Wayne Airport Orange County (SNA)plane plane DEN - SNA
    6h 45m
    $237–479

  6. Fly from Pueblo Memorial Airport

    1. Fly from Pueblo Memorial Airport (PUB) to John Wayne Airport Orange County (SNA)plane plane PUB - SNA
    4h 42m
    $187–642

  7. Bus via Las Cruces

    1. Take the bus from Pueblo, CO to Las Cruces, NMbus bus Denver to El Paso
    2. Take the bus from Las Cruces, NM to Santa Anabus bus El Paso
    28h 40m
    $184–264

Pueblo to Santa Ana by bus and train

Calendar7Weekly Services
Duration25h 18mAverage Duration
Ticket$386Cheapest Price
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Questions & Answers

Map of how to get from Pueblo to Santa Ana.ExpandLaunch map view
  • Distance: 872.9 mi
  • Duration: 5h 36m

What companies run services between Pueblo, CO, USA and Santa Ana, CA, USA?

You can take a bus from Pueblo Transit to Santa Ana Bus Stop via Denver Union Station and Las Vegas Bus Terminal in around 25h 25m. Alternatively, Key Lime, United Airlines, and Southwest Airlines fly from Pueblo Memorial Airport (PUB) to John Wayne Airport Orange County (SNA) once daily.

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