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How to get fromPueblo to Santa Anaby bus, plane, train, bus (Greyhound, Flixbus), or car

Find Transport to Santa Ana

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There are 8 ways to get from Pueblo to Santa Ana by bus, plane, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Colorado Springs Airport, fly to John Wayne Airport Orange County

    best
    1. Take the bus from Pueblo, CO to Colorado Springsbus bus
    2. Fly from Colorado Springs Airport (COS) to John Wayne Airport Orange County (SNA)plane plane COS - SNA
    5h 54m
    $169–591

  2. Bus to Colorado Springs Airport, fly to San Diego International Airport, train

    cheapest
    1. Take the bus from Pueblo, CO to Colorado Springsbus bus
    2. Fly from Colorado Springs Airport (COS) to San Diego International Airport (SAN)plane plane COS - SAN
    3. Take the train from San Diego to Santa Anatrain train
    9h 8m
    $167–531

  3. Bus, train

    1. Take the bus from Pueblo, CO to Las Vegas Transportation Centerbus bus Denver / ...
    2. Take the train from Las Vegas Amtrak Station to Fullerton Amtrak Stationtrain train Southwest Chief
    25h 21m
    $616–934

  4. Bus

    1. Take the bus from Pueblo Transit to Denver Union Stationbus bus
    2. Take the bus from Denver Union Station to Las Vegas Bus Terminalbus bus
    3. Take the bus from Las Vegas Bus Terminal to Santa Ana Bus Stopbus bus
    25h 25m
    $193–315

  5. Drive  1,055.9 mi

    1. Drive from Pueblo to Santa Anacar car 1,055.9 mi
    17h 33m
    $193–279

  6. Bus to Denver, fly to John Wayne Airport Orange County

    1. Take the bus from Pueblo Transit to Denver Union Stationbus bus
    2. Fly from Denver (DEN) to John Wayne Airport Orange County (SNA)plane plane DEN - SNA
    6h 45m
    $227–555

  7. Fly Pueblo Memorial Airport to John Wayne Airport Orange County

    1. Fly from Pueblo Memorial Airport (PUB) to John Wayne Airport Orange County (SNA)plane plane PUB - SNA
    4h 48m
    $177–642

  8. Bus via Las Cruces

    1. Take the bus from Pueblo to Las Crucesbus bus Lxus 1121 / ...
    2. Take the bus from Las Cruces, NM to Santa Anabus bus El Paso
    28h 25m
    $184–264

Pueblo to Santa Ana by bus and train

Calendar7Weekly Services
Duration25h 21mAverage Duration
Ticket$616Cheapest Price
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Comparing Your Travel Options

Map of how to get from Pueblo to Santa Ana.ExpandLaunch map view
  • Distance: 876.7 mi
  • Duration: 5h 54m

What companies run services between Pueblo, CO, USA and Santa Ana, CA, USA?

You can take a bus from Pueblo Transit to Santa Ana Bus Stop via Denver Union Station and Las Vegas Bus Terminal in around 25h 25m. Alternatively, Key Lime, Southwest Airlines, and American Airlines fly from Pueblo Memorial Airport (PUB) to John Wayne Airport Orange County (SNA) twice daily.

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