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How to get fromPuerto Iguazú to Santiagoby plane, bus, or car

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There are 6 ways to get from Puerto Iguazú to Santiago by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Cataratas Del Iguazú International Airport

    best
    1. Fly from Cataratas Del Iguazú International Airport (IGR) to Comodoro Arturo Merino Benítez International Airport (SCL)plane plane IGR - SCL
    8h 7m
    $112–278

  2. Bus via Córdoba

    cheapest
    1. Take the bus from Terminal de Ómnibus de Puerto Iguazú to Terminal de Ómnibus Córdoba T1bus bus
    2. Take the bus from Terminal Villa Carlos Paz to Terminal Mendozabus bus
    3. Take the bus from Terminal Mendoza to Terminal Sur de Santiagobus bus
    41h 48m
    $109–213

  3. Bus via Uruguaiana

    1. Take the bus from Terminal de Ómnibus de Puerto Iguazú to Paso De Los Libresbus bus
    2. Take the bus from Estação Rodoviária de Uruguaiana to Terminal Sur de Santiagobus bus Santiago
    38h 3m
    $189–292

  4. Drive 2,286.4 km

    1. Drive from Puerto Iguazú to Santiagocar car 2,286.4 km
    29h 58m
    $299–431

  5. Bus to Foz Do Iguaçu / Cataratas International Airport, fly

    1. Take the bus from Terminal de Transportes Urbano - Foz do Iguaçu to Foz do Iguaçu Airport - IGUbus bus
    2. Fly from Foz Do Iguaçu / Cataratas International Airport (IGU) to Comodoro Arturo Merino Benítez International Airport (SCL)plane plane IGU - SCL
    6h 47m
    $110–353

  6. Bus

    1. Take the bus from Terminal de Ómnibus de Puerto Iguazú to Terminal Mendozabus bus
    2. Take the bus from Terminal Mendoza to Terminal Sur de Santiagobus bus Santiago
    40h
    $115–199

Puerto Iguazú to Santiago by bus

Calendar7Weekly Buses
Duration40hAverage Duration
Ticket$115Cheapest Price
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Questions & Answers

Map of how to get from Puerto Iguazú to Santiago.ExpandLaunch map view
  • Distance: 1,823.4 km
  • Duration: 8h 7m

What companies run services between Puerto Iguazú, Argentina and Santiago, Chile?

Aerolíneas Argentinas, JetSMART, and LATAM Chile fly from Cataratas Del Iguazú International Airport (IGR) to Comodoro Arturo Merino Benítez International Airport (SCL) twice daily. Alternatively, you can take a bus from Terminal de Ómnibus de Puerto Iguazú to Terminal Sur de Santiago via Terminal Ómnibus Paso De Los Libres and Estação Rodoviária de Uruguaiana in around 38h 3m.

Airlines
Bus operators

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