There are 4 ways to get from Puerto Maldonado to Santa Cruz by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Puerto Maldonado (PEM) to Viru Viru International Airport (VVI)plane PEM - VVI
10h 51m$216–757Bus via Cochabamba
- Take the bus from Puerto Maldonado to Punobus
- Take the bus from Puno to La Pazbus
- Take the bus from La Paz to Cochabambabus
- Take the bus from Cochabamba to Santa Cruz de la Sierrabus
34h 1m$257–306Drive 1,621.3 km
- Drive from Puerto Maldonado to Santa Cruz de la Sierracar 1,621.3 km
26h 14m$244–352Bus
- Take the bus from Puerto Maldonado to Punobus
- Take the bus from Puno to La Pazbus
- Take the bus from La Paz to Santa Cruzbus
37h 34m$253–360
Puerto Maldonado (PEM) to Viru Viru International Airport (VVI) flights
Questions & Answers
The cheapest way to get from Puerto Maldonado to Santa Cruz is to bus via Cochabamba which costs $250 - $310 and takes 34h 1m.
The fastest way to get from Puerto Maldonado to Santa Cruz is to fly which takes 10h 51m and costs $210 - $800.
No, there is no direct bus from Puerto Maldonado to Santa Cruz. However, there are services departing from Puerto Maldonado and arriving at Santa Cruz de la Sierra via Puno, La Paz, Plaza Colón and Cochabamba. The journey, including transfers, takes approximately 34h 1m.
The distance between Puerto Maldonado and Santa Cruz is 885 km. The road distance is 1621.3 km.
The best way to get from Puerto Maldonado to Santa Cruz without a car is to bus via Cochabamba which takes 34h 1m and costs $250 - $310.
It takes approximately 10h 51m to get from Puerto Maldonado to Santa Cruz, including transfers.
Puerto Maldonado to Santa Cruz bus services, operated by Transportes Reyna, depart from Puerto Maldonado station.
The best way to get from Puerto Maldonado to Santa Cruz is to fly which takes 10h 51m and costs $210 - $800. Alternatively, you can bus via Cochabamba, which costs $250 - $310 and takes 34h 1m.
Puerto Maldonado to Santa Cruz bus services, operated by Transportes Reyna, arrive at Puno station.
Santa Cruz is 1h ahead of Puerto Maldonado. It is currently 4:37 PM in Puerto Maldonado and 5:37 PM in Santa Cruz.
What companies run services between Puerto Maldonado, Peru and Santa Cruz, Bolivia?
LATAM Chile and Boliviana de Aviación fly from Puerto Maldonado (PEM) to Viru Viru International Airport (VVI) twice daily. Alternatively, you can take a bus from Puerto Maldonado to Santa Cruz de la Sierra via Puno, La Paz, Cochabamba, Plaza Colón, Avenida República, Cochabamba, and Santa Cruz de la Sierra in around 34h 1m.
- Website
- latam.com
Flights from Puerto Maldonado to Viru Viru International Airport via Lima
- Ave. Duration
- 10h 15m
- When
- Wednesday and Thursday
- Estimated price
- $210–750
Flights from Puerto Maldonado to Viru Viru International Airport via Cuzco, Lima
- Ave. Duration
- 11h 25m
- When
- Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $210–750
- Website
- boa.bo
Flights from Puerto Maldonado to Viru Viru International Airport via Lima
- Ave. Duration
- 10h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- $250–750
- Phone
- +51 9 6629 9448
- [email protected]
- Website
- reyna.com.pe
Bus from Puerto Maldonado to Puno
- Ave. Duration
- 10h
- Frequency
- Twice daily
- Estimated price
- $23–45
- Book at
- Transportes Reyna
Bus from Puerto Maldonado to Puno
- Ave. Duration
- 10h
- Frequency
- Twice daily
- Estimated price
- $23–45
- Book at
- Transportes Reyna
- Phone
- +591 76760037
- Website
- facebook.com
Bus from Puno to La Paz
- Ave. Duration
- 7h 30m
- Frequency
- Twice daily
- Estimated price
- $7–110
- Schedules at
- ticketsbolivia.com
- Book at
- ticketsbolivia.com
Bus from Puno to La Paz
- Ave. Duration
- 7h 30m
- Frequency
- Twice daily
- Estimated price
- $7–110
- Schedules at
- ticketsbolivia.com
- Book at
- ticketsbolivia.com
- Phone
- +591 22283843
- [email protected]
- Website
- facebook.com
Bus from Puno to La Paz
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- $220–250
- Book at
- Tickets Bolivia
Bus from Puno to La Paz
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- $220–250
- Book at
- Tickets Bolivia
- Phone
- +59176401000
- Website
- facebook.com
Bus from La Paz to Cochabamba
- Ave. Duration
- 7h 45m
- Frequency
- 5 times a day
- Estimated price
- $9
- Book at
- ticketsbolivia.com.bo
- Phone
- +591 72201573
- [email protected]
- Website
- Minibuses Trans Carrasco tropical
Bus from Cochabamba to Santa Cruz de la Sierra
- Ave. Duration
- 6h
- Frequency
- Hourly
- Estimated price
- $2
- Website
- Minibuses Trans Carrasco tropical
- Phone
- +591-72233555
- [email protected]
- Website
- Trans Copacabana SA
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- 4 times a day
- Estimated price
- $19–25
- Schedules at
- Trans Copacabana SA
- Phone
- +591 7297 1111
- Website
- Expreso del Sur
Bus from La Paz to Santa Cruz
- Ave. Duration
- 14h
- Frequency
- Once daily
- Estimated price
- $40–55
- Schedules at
- Expreso del Sur
- Phone
- +591 69414917
- Website
- Flota Bolivar
Bus from La Paz to Santa Cruz
- Ave. Duration
- 16h 20m
- Frequency
- Once daily
- Estimated price
- $7–19
- Schedules at
- Flota Bolivar
- Normal
- $7–10
- Semicama
- $11–14
- Cama
- $17–19
- Phone
- +591 69416892
- [email protected]
- Website
- Cosmos
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- Once daily
- Estimated price
- $9–13
- Schedules at
- Cosmos
- Phone
- +59176400493
- Website
- flotaeldorado.com
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- Once daily
- Estimated price
- $19–65
- Schedules at
- flotaeldorado.com
- Book at
- flotaeldorado.com
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More Questions & Answers
Yes, the driving distance between Puerto Maldonado to Santa Cruz is 1621 km. It takes approximately 26h 14m to drive from Puerto Maldonado to Santa Cruz.
There are 731+ hotels available in Santa Cruz.





















