Rome2Rio

How to get fromPuerto Rico to Santiago de Cubaby plane or bus

Find Transport to Santiago de Cuba

See all options
QR code to download the Rome2Rio app

Download the Rome2Rio travel app

Scan QR code with your phone to download the app

Download on the App StoreGet it on Google Play

There are 4 ways to get from Puerto Rico to Santiago de Cuba by plane or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Eugenio María De Hostos Airport to Antonio Maceo International Airport

    best
    1. Fly from Eugenio María De Hostos Airport (MAZ) to Antonio Maceo International Airport (SCU)plane plane MAZ - SCU
    19h 34m
    $154–704
  2. Fly Luis Munoz Marin International Airport to Antonio Maceo International Airport

    1. Fly from Luis Munoz Marin International Airport (SJU) to Antonio Maceo International Airport (SCU)plane plane SJU - SCU
    18h 58m
    $228–878
  3. Fly Isla Grande Airport to Antonio Maceo International Airport

    1. Fly from Isla Grande Airport (SIG) to Antonio Maceo International Airport (SCU)plane plane SIG - SCU
    22h 48m
    $843–2,075
  4. Fly Luis Munoz Marin International Airport to Frank País International Airport, bus

    1. Fly from Luis Munoz Marin International Airport (SJU) to Frank País International Airport (HOG)plane plane SJU - HOG
    2. Take the bus from Holguin Airport to Terminal de Ómnibus Nacionales Santiago de Cubabus bus
    13h 37m
    $190–697

Eugenio María De Hostos Airport (MAZ) to Antonio Maceo International Airport (SCU) flights

Calendar6Weekly Planes
Duration19h 40mAverage Duration
Ticket$157Cheapest Price
See schedules

Comparing Your Travel Options

What companies run services between Puerto Rico and Santiago de Cuba?

Cape Air, American Airlines, and two other airlines fly from Eugenio María De Hostos Airport (MAZ) to Antonio Maceo International Airport (SCU) 6 times a week.

Airlines
Bus operators

Want to know more about travelling around the world?

Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including 5 delightfully under-the-radar French towns you need to visit, How do I get from Sydney to Melbourne, and Need to know: Greyhound - to help you get the most out of your next trip.