There are 5 ways to get from Puno to Santa Cruz by shuttle, bus, plane, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Shuttle, bus to El Alto International Airport, fly
best- Take a shuttle bus from Puno to Desaguadero
- Take the bus from Desaguadero to La Pazbus
- Fly from El Alto International Airport (LPB) to Viru Viru International Airport (VVI)plane LPB - VVI
9h 13m$245–365Tour, bus
cheapest- Take a shuttle bus from Puno to La Paz
- Take the bus from La Paz to Cochabambabus
- Take the bus from Cochabamba to Santa Cruz de la Sierrabus
28h 1m$63–64Bus
- Take the bus from Puno to La Pazbus Puno
- Take the bus from La Paz to Santa Cruzbus La Paz
26h 34m$237–316Drive 1,039.7 km
- Drive from Puno to Santa Cruz de la Sierracar 1,039.7 km
16h 10m$157–226Fly from Inca Manco Cápac International Airport
- Fly from Inca Manco Cápac International Airport (JUL) to Viru Viru International Airport (VVI)plane JUL - VVI
12h 30m$471–681
El Alto International Airport (LPB) to Viru Viru International Airport (VVI) flights
Questions & Answers
The cheapest way to get from Puno to Santa Cruz is to Tour and bus which costs $63 - $64 and takes 28h 1m.
The fastest way to get from Puno to Santa Cruz is to shuttle and bus and fly which takes 9h 13m and costs $240 - $370.
No, there is no direct bus from Puno to Santa Cruz. However, there are services departing from Puno and arriving at Santa Cruz via La Paz. The journey, including transfers, takes approximately 26h 34m.
The distance between Puno and Santa Cruz is 847 km. The road distance is 1039.7 km.
The best way to get from Puno to Santa Cruz without a car is to bus which takes 26h 34m and costs $230 - $320.
It takes approximately 9h 13m to get from Puno to Santa Cruz, including transfers.
Puno to Santa Cruz bus services, operated by Trans Titicaca, depart from Puno station.
The best way to get from Puno to Santa Cruz is to bus which takes 26h 34m and costs $230 - $320. Alternatively, you can fly, which costs $470 - $700 and takes 12h 30m.
Puno to Santa Cruz bus services, operated by Trans Titicaca, arrive at La Paz station.
Santa Cruz is 1h ahead of Puno. It is currently 11:48 AM in Puno and 12:48 PM in Santa Cruz.
What companies run services between Puno, Peru and Santa Cruz, Bolivia?
You can take a bus from Puno to Santa Cruz de la Sierra via La Paz and Santa Cruz in around 26h 34m. Alternatively, LATAM Chile, Sky Airline, and Boliviana de Aviación fly from Inca Manco Cápac International Airport (JUL) to Viru Viru International Airport (VVI) twice daily.
- Website
- boa.bo
Flights from El Alto International Airport to Viru Viru International Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $100–220
Flights from El Alto International Airport to Viru Viru International Airport via Cochabamba
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- $100–220
Flights from Inca Manco Cápac International Airport to Viru Viru International Airport via Lima
- Ave. Duration
- 9h 10m
- When
- Every day
- Estimated price
- $330–1,100
- Phone
- +51 95 175 5337
- [email protected]
- Website
- Sacred Lake Titikaka
Shuttle from Puno to Desaguadero
- Ave. Duration
- 1h 45m
- Frequency
- On demand
- Estimated price
- $140
- Website
- Sacred Lake Titikaka
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More Questions & Answers
Yes, the driving distance between Puno to Santa Cruz is 1040 km. It takes approximately 16h 10m to drive from Puno to Santa Cruz.
There are 736+ hotels available in Santa Cruz.

