There are 6 ways to get from Puno to Santa Cruz by shuttle, bus, plane, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Shuttle, bus to El Alto International Airport, fly
best- Take a shuttle bus from Puno to Desaguadero
- Take the bus from Desaguadero to La Pazbus
- Fly from El Alto International Airport (LPB) to Viru Viru International Airport (VVI)plane LPB - VVI
9h 13m$245–365Tour, bus
cheapest- Take a shuttle bus from Puno to La Paz
- Take the bus from La Paz to Cochabambabus
- Take the bus from Cochabamba to Santa Cruz de la Sierrabus
28h 1m$62–63Bus
- Take the bus from Puno to La Pazbus Puno
- Take the bus from La Paz to Santa Cruzbus La Paz
26h 34m$236–306Drive 1,039.7 km
- Drive from Puno to Santa Cruz de la Sierracar 1,039.7 km
16h 10m$157–226Fly from Inca Manco Cápac International Airport
- Fly from Inca Manco Cápac International Airport (JUL) to Viru Viru International Airport (VVI)plane JUL - VVI
9h 25m$471–631Bus to Rodríguez Ballón International Airport, fly
- Take the bus from Puno to Arequipabus
- Fly from Rodríguez Ballón International Airport (AQP) to Viru Viru International Airport (VVI)plane AQP - VVI
15h 19m$323–542
El Alto International Airport (LPB) to Viru Viru International Airport (VVI) flights
Comparing Your Travel Options
The cheapest way to get from Puno to Santa Cruz is to Tour and bus which costs $62 - $63 and takes 28h 1m.
The fastest way to get from Puno to Santa Cruz is to shuttle and bus and fly which takes 9h 13m and costs $240 - $370.
No, there is no direct bus from Puno to Santa Cruz. However, there are services departing from Puno and arriving at Santa Cruz via La Paz. The journey, including transfers, takes approximately 26h 34m.
The distance between Puno and Santa Cruz is 847 km. The road distance is 1039.7 km.
The best way to get from Puno to Santa Cruz without a car is to bus which takes 26h 34m and costs $230 - $310.
It takes approximately 9h 13m to get from Puno to Santa Cruz, including transfers.
Puno to Santa Cruz bus services, operated by Trans Titicaca, depart from Puno station.
The best way to get from Puno to Santa Cruz is to bus which takes 26h 34m and costs $230 - $310. Alternatively, you can fly, which costs $470 - $650 and takes 9h 25m.
Puno to Santa Cruz bus services, operated by Trans Titicaca, arrive at La Paz station.
Santa Cruz is 1h ahead of Puno. It is currently 10:40 PM in Puno and 11:40 PM in Santa Cruz.
What companies run services between Puno, Peru and Santa Cruz, Bolivia?
You can take a bus from Puno to Santa Cruz de la Sierra via La Paz and Santa Cruz in around 26h 34m. Alternatively, LATAM Chile, Boliviana de Aviación, and Sky Airline fly from Inca Manco Cápac International Airport (JUL) to Viru Viru International Airport (VVI) once daily.
- Website
- boa.bo
Flights from El Alto International Airport to Viru Viru International Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $100–220
Flights from El Alto International Airport to Viru Viru International Airport via Cochabamba
- Ave. Duration
- 2h 17m
- When
- Every day
- Estimated price
- $100–220
Flights from Inca Manco Cápac International Airport to Viru Viru International Airport via Lima
- Ave. Duration
- 6h 5m
- When
- Wednesday and Sunday
- Estimated price
- $330–1,000
Flights from Rodríguez Ballón International Airport to Viru Viru International Airport via Lima
- Ave. Duration
- 5h 20m
- When
- Wednesday
- Estimated price
- $240–750
- Website
- latam.com
Flights from El Alto International Airport to Viru Viru International Airport
- Ave. Duration
- 1h 13m
- When
- Thursday and Saturday
- Estimated price
- $75–500
Flights from Inca Manco Cápac International Airport to Viru Viru International Airport via Lima
- Ave. Duration
- 6h 55m
- When
- Wednesday and Sunday
- Estimated price
- $290–1,000
Flights from Inca Manco Cápac International Airport to Viru Viru International Airport via Lima, El Alto International Airport
- Ave. Duration
- 12h 4m
- When
- Wednesday
- Estimated price
- $290–1,000
Flights from Inca Manco Cápac International Airport to Viru Viru International Airport via Lima, Santiago
- Ave. Duration
- 12h 56m
- When
- Tuesday
- Estimated price
- $480–1,500
Flights from Rodríguez Ballón International Airport to Viru Viru International Airport via Lima
- Ave. Duration
- 6h 15m
- When
- Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $210–750
Flights from Rodríguez Ballón International Airport to Viru Viru International Airport via Cuzco, Lima
- Ave. Duration
- 9h 30m
- When
- Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $220–750
- Website
- ecojet.bo
Flights from El Alto International Airport to Viru Viru International Airport
- Ave. Duration
- 1h 5m
- When
- Monday, Wednesday, Sunday, and Friday
- Estimated price
- $50–320
- Phone
- +51 95 175 5337
- [email protected]
- Website
- Sacred Lake Titikaka
Shuttle from Puno to Desaguadero
- Ave. Duration
- 1h 45m
- Frequency
- On demand
- Estimated price
- $140
- Website
- Sacred Lake Titikaka
Bus from Desaguadero to La Paz
- Ave. Duration
- 2h
- Frequency
- 4 times a day
- Estimated price
- $2
- Phone
- +591 76760037
- Website
- facebook.com
Bus from Puno to La Paz
- Ave. Duration
- 7h 30m
- Frequency
- Twice daily
- Estimated price
- $7–110
- Schedules at
- ticketsbolivia.com
- Book at
- ticketsbolivia.com
- Phone
- +591 2228 3843
- [email protected]
- Website
- facebook.com
Bus from Puno to La Paz
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- $220–250
- Book at
- Tickets Bolivia
- Phone
- +591-72233555
- [email protected]
- Website
- Trans Copacabana SA
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- 4 times a day
- Estimated price
- $18–24
- Schedules at
- Trans Copacabana SA
- Phone
- +591 71861725
- Website
- Expreso del Sur
Bus from La Paz to Santa Cruz
- Ave. Duration
- 14h
- Frequency
- Once daily
- Estimated price
- $40–55
- Schedules at
- Expreso del Sur
- Phone
- +591 69414917
- Website
- Flota Bolivar
Bus from La Paz to Santa Cruz
- Ave. Duration
- 16h 20m
- Frequency
- Once daily
- Estimated price
- $7–19
- Schedules at
- Flota Bolivar
- Normal
- $7–10
- Semicama
- $10–14
- Cama
- $16–19
- Phone
- +591 69416892
- [email protected]
- Website
- Cosmos
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- Once daily
- Estimated price
- $9–13
- Schedules at
- Cosmos
- Phone
- +59176400493
- Website
- flotaeldorado.com
Bus from La Paz to Santa Cruz
- Ave. Duration
- 18h
- Frequency
- Once daily
- Estimated price
- $18–35
- Schedules at
- flotaeldorado.com
- Book at
- flotaeldorado.com
- Phone
- +51 987 048 942
- [email protected]
- Website
- transzela.com.pe
Bus from Puno to Arequipa
- Ave. Duration
- 6h
- Frequency
- Every 3 hours
- Estimated price
- $12
- Schedules at
- transzela.com.pe
- Book at
- transzela.com.pe
- Phone
- +51 914 879 671
- [email protected]
- Website
- facebook.com
Bus from Puno to Arequipa
- Ave. Duration
- 4h 18m
- Frequency
- Twice daily
- Estimated price
- $15
- Schedules at
- facebook.com
- Phone
- +51 9 6629 9448
- [email protected]
- Website
- reyna.com.pe
Bus from Puno to Arequipa
- Ave. Duration
- 5h 15m
- Frequency
- Twice daily
- Estimated price
- $11–19
- Book at
- Transportes Reyna
- Website
- Cosmos Bus
Bus from Puno to Arequipa
- Ave. Duration
- 5h 23m
- Frequency
- Twice daily
- Estimated price
- $17–24
- Schedules at
- Cosmos Bus
- Phone
- +51 511 418 1111
- [email protected]
- Website
- CIVA
Bus from Puno to Arequipa
- Ave. Duration
- 5h 30m
- Frequency
- Twice daily
- Estimated price
- $7–50
- Schedules at
- CIVA
- Phone
- +51 928351548
- [email protected]
- Website
- facebook.com
Bus from Puno to Arequipa
- Ave. Duration
- 5h 30m
- Frequency
- Twice daily
- Schedules at
- facebook.com
- Phone
- +51 1 311 5050
- Website
- Cruz del Sur
Bus from Puno to Arequipa
- Ave. Duration
- 6h
- Frequency
- Twice daily
- Estimated price
- $14–23
- Website
- Cruz del Sur
Bus from Puno to Arequipa
- Ave. Duration
- 5h
- Frequency
- Once daily
- Estimated price
- $8–12
- Schedules at
- Expreso Turismo San Martin Nobleza
- Phone
- +51 951 921 780
- Website
- Expreso Sur Oriente
Bus from Puno to Arequipa
- Ave. Duration
- 5h 20m
- Frequency
- Once daily
- Estimated price
- $15
- Schedules at
- Expreso Sur Oriente
- Phone
- +51 84 245 171
- [email protected]
- Website
- Turismo Mer
Bus from Puno to Arequipa
- Ave. Duration
- 6h 30m
- Frequency
- Once daily
- Estimated price
- $18–45
- Website
- Turismo Mer
- Phone
- +51 978645747
- [email protected]
- Website
- Turismo Real Dorado
Bus from Puno to Arequipa
- Ave. Duration
- 8h
- Frequency
- Once daily
- Estimated price
- $11–18
- Schedules at
- Turismo Real Dorado
- Phone
- +51 959 570 871
- [email protected]
- Website
- Romeliza
Bus from Puno to Arequipa
- Ave. Duration
- 5h
- Frequency
- Once a week
- Schedules at
- Romeliza
- Phone
- +51 051 630 257
- [email protected]
- Website
- Rumbo Explora
Shuttle from Puno to La Paz
- Ave. Duration
- 12h 30m
- Frequency
- Hourly
- Estimated price
- $50
- Schedules at
- Rumbo Explora
- Phone
- +59176401000
- Website
- facebook.com
Bus from La Paz to Cochabamba
- Ave. Duration
- 7h 45m
- Frequency
- 5 times a day
- Estimated price
- $9
- Book at
- BusBud - Flota Urus
- Phone
- +591 72201573
- [email protected]
- Website
- Minibuses Trans Carrasco tropical
Bus from Cochabamba to Santa Cruz de la Sierra
- Ave. Duration
- 6h
- Frequency
- Hourly
- Estimated price
- $2
- Website
- Minibuses Trans Carrasco tropical
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Booking & Getting There
Yes, the driving distance between Puno to Santa Cruz is 1040 km. It takes approximately 16h 10m to drive from Puno to Santa Cruz.
There are 770+ hotels available in Santa Cruz.
















































