There are 7 ways to get from Punta Arenas to La Serena by plane, bus (Flixbus), bus, ferry, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Presidente Carlos Ibáñez Del Campo International Airport
best- Fly from Presidente Carlos Ibáñez Del Campo International Airport (PUQ) to La Florida Airport (LSC)plane PUQ - LSC
7h 3m$100–250Bus to Puerto Natales, fly
cheapest- Take the bus from Terminal Punta Arenas - Buses Fernandez to Terminal Rodoviariobus
- Fly from Puerto Natales (PNT) to La Florida Airport (LSC)plane PNT - LSC
9h 18m$58–214Bus via Bariloche
- Take the bus from Terminal Punta Arenas - Buses Barria to Terminal de Ómnibus de Río Gallegosbus
- Take the bus from Terminal de Ómnibus de Río Gallegos to Terminal de Omnibus Barilochebus
- Take the bus from Bariloche to Terminal Surbus
- Take the bus from Santiago to Terminal de buses La Serenabus
2d 6h$216–386Bus, ferry
- Take the bus from Terminal Bus-Sur to Terminal Rodoviariobus
- Take the ferry from Puerto Natales to Puerto Monttferry
- Take the bus from Puerto Montt to Santiagobus
- Take the bus from Terminal San Borja to Terminal de buses La Serenabus
4d 13h$448–1,148Drive 3,428 km
- Drive from Punta Arenas to La Serenacar 3,428 km
40h$423–611Bus
- Take the bus from Terminal Punta Arenas - Buses Barria to Terminal de Ómnibus de Río Gallegosbus
- Take the bus from Terminal de Ómnibus de Río Gallegos to Vicuña Mackennabus
- Take the bus from Vicuña Mackenna to Ediro San Luisbus
- Take the bus from Ediro San Luis to Terminal Mendozabus
- Take the bus from Terminal Mendoza to Terminal de buses La Serenabus
2d 12h$235–442Bus #2
- Take the bus from Terminal Punta Arenas - Buses Barria to Terminal de Ómnibus de Río Gallegosbus
- Take the bus from Terminal de Ómnibus de Río Gallegos to Terminal de Omnibus Barilochebus
- Take the bus from Bariloche Terminal to Terminal De Ómnibus San Juanbus
- Take the bus from Terminal De Ómnibus San Juan to Terminal de buses La Serenabus
2d 20h$235–455
Presidente Carlos Ibáñez Del Campo International Airport (PUQ) to La Florida Airport (LSC) flights
Comparing Your Travel Options
The cheapest way to get from Punta Arenas to La Serena is to bus and fly which costs $55 - $220 and takes 9h 18m.
The fastest way to get from Punta Arenas to La Serena is to fly which takes 7h 3m and costs $100 - $250.
No, there is no direct bus from Punta Arenas to La Serena. However, there are services departing from Terminal Punta Arenas - Buses Barria and arriving at Terminal de buses La Serena via Terminal de Ómnibus de Río Gallegos, Bariloche, PI341-Parada 1 / and Santiago. The journey, including transfers, takes approximately 2 days 6h.
The distance between Punta Arenas and La Serena is 2589 km. The road distance is 3428 km.
The best way to get from Punta Arenas to La Serena without a car is to bus via Bariloche which takes 2 days 6h and costs $210 - $390.
It takes approximately 7h 3m to get from Punta Arenas to La Serena, including transfers.
Punta Arenas to La Serena bus services, operated by Buses Barria, depart from Terminal Punta Arenas - Buses Barria station.
The best way to get from Punta Arenas to La Serena is to fly which takes 7h 3m and costs $100 - $250. Alternatively, you can bus via Bariloche, which costs $210 - $390 and takes 2 days 6h.
Punta Arenas to La Serena bus services, operated by Buses Barria, arrive at Terminal de Ómnibus de Río Gallegos station.
Yes, the driving distance between Punta Arenas to La Serena is 3428 km. It takes approximately 40h to drive from Punta Arenas to La Serena.
What companies run services between Punta Arenas, Chile and La Serena, Chile?
LATAM Chile flies from Presidente Carlos Ibáñez Del Campo International Airport (PUQ) to La Florida Airport (LSC) 6 times a week. Alternatively, you can take a bus from Terminal Punta Arenas - Buses Barria to Terminal de buses La Serena via Terminal de Ómnibus de Río Gallegos, Bariloche, Terminal Sur, PI341-Parada 1 /, PI1179-Parada / Terminal San Borja, and Santiago in around 2d 6h.
- Website
- latam.com
Flights from Presidente Carlos Ibáñez Del Campo International Airport to La Florida Airport via Santiago
- Ave. Duration
- 5h 52m
- When
- Sunday to Saturday
- Estimated price
- $90–410
Flights from Presidente Carlos Ibáñez Del Campo International Airport to La Florida Airport via Puerto Montt, Santiago
- Ave. Duration
- 7h 59m
- When
- Friday and Monday
- Estimated price
- $95–410
Flights from Puerto Natales to La Florida Airport via Santiago
- Ave. Duration
- 5h 9m
- When
- Saturday and Sunday
- Estimated price
- $110–490
Flights from Puerto Natales to La Florida Airport via Puerto Montt, Santiago
- Ave. Duration
- 7h 27m
- When
- Saturday and Sunday
- Estimated price
- $110–490
- Website
- skyairline.com
Flights from Puerto Natales to La Florida Airport via Santiago
- Ave. Duration
- 5h 13m
- When
- Sunday
- Estimated price
- $45–200
- Phone
- +56 61 263 9157
- [email protected]
- Website
- Buses Barria
Bus from Terminal Punta Arenas - Buses Barria to Terminal de Ómnibus de Río Gallegos
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $21
- Schedules at
- Buses Barria
Bus from Terminal Punta Arenas - Buses Barria to Terminal de Ómnibus de Río Gallegos
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $21
- Schedules at
- Buses Barria
Bus from Terminal Punta Arenas - Buses Barria to Terminal de Ómnibus de Río Gallegos
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $21
- Schedules at
- Buses Barria
- Phone
- 0800-3331188
- [email protected]
- Website
- taqsa.com.ar
Bus from Terminal de Ómnibus de Río Gallegos to Terminal de Omnibus Bariloche
- Ave. Duration
- 23h 40m
- Frequency
- Once a week
- Estimated price
- $100–194
- Schedules at
- taqsa.com.ar
- Semibed
- $100–140
- Bed
- $110–170
Bus from Terminal de Ómnibus de Río Gallegos to Terminal de Omnibus Bariloche
- Ave. Duration
- 23h 40m
- Frequency
- Once a week
- Estimated price
- $100–194
- Schedules at
- taqsa.com.ar
- Semibed
- $100–140
- Bed
- $110–170
- Phone
- 0810 122 1122
- [email protected]
- Website
- andesmar.com
Bus from Bariloche to Terminal Sur
- Ave. Duration
- 18h
- Frequency
- Twice daily
- Estimated price
- $45–85
- Book at
- andesmar.com
- Bed
- $60–85
- Semi bed
- $45–70
Bus from Ediro San Luis to Terminal Mendoza
- Ave. Duration
- 4h 10m
- Frequency
- 5 times a day
- Estimated price
- $11–20
- Schedules at
- andesmar.com
- Book at
- andesmar.com
- Bed
- $13–20
- Semi bed
- $11–16
- Website
- Flixbus Chile
Bus from Santiago to Terminal de buses La Serena
- Ave. Duration
- 6h 10m
- Frequency
- Hourly
- Estimated price
- $50–80
- Schedules at
- Flixbus Chile
Bus from Puerto Montt to Santiago
- Ave. Duration
- 13h 40m
- Frequency
- Twice daily
- Estimated price
- $100–150
- Schedules at
- Flixbus Chile
- Phone
- +56 61 261 4224
- [email protected]
- Website
- bussur.com
Bus from Terminal Bus-Sur to Terminal Rodoviario
- Ave. Duration
- 3h 15m
- Frequency
- Hourly
- Estimated price
- $12–28
- Schedules at
- bussur.com
- Book at
- bussur.com
- Semi Cama
- $19–28
- Phone
- +56 22 3813 550
- [email protected]
- Website
- plusschile.cl
Bus from Terminal San Borja to Terminal de buses La Serena
- Ave. Duration
- 6h 20m
- Frequency
- Twice daily
- Estimated price
- $13–26
- Book at
- Recorrido Pluss Chile
- Semi Cama
- $14–18
- Cama
- $20–26
- Phone
- +56 22 683 8528
- [email protected]
- Website
- Andimar
Bus from Terminal San Borja to Terminal de buses La Serena
- Ave. Duration
- 6h 10m
- Frequency
- Hourly
- Estimated price
- $11–27
- Schedules at
- Andimar
- Semi Cama
- $11–15
- Cama
- $16–27
- Phone
- +56 600 600 0018
- [email protected]
- Website
- pullmanbus.cl
Bus from Terminal San Borja to Terminal de buses La Serena
- Ave. Duration
- 6h 20m
- Frequency
- Hourly
- Estimated price
- $21–40
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $24–40
- Phone
- +56 22 822 7500
- [email protected]
- Website
- turbus.cl
Bus from Terminal San Borja to Terminal de buses La Serena
- Semi Cama
- $16–23
- Cama
- $23–35
- Premium
- $55–70
- Phone
- +56 51 221 5300
- [email protected]
- Website
- Buses Romani
Bus from Terminal San Borja to Terminal de buses La Serena
- Ave. Duration
- 6h 30m
- Frequency
- Hourly
- Estimated price
- $9–25
- Schedules at
- Buses Romani
- Semi
- $9–11
- Salon
- $20–25
- [email protected]
- Website
- Pullman San Andres
Bus from Terminal San Borja to Terminal de buses La Serena
- Ave. Duration
- 6h 30m
- Frequency
- Every 4 hours
- Estimated price
- $35–55
- Schedules at
- Pullman San Andres
- Semi Cama
- $35–50
- Cama
- $35–55
Bus from Terminal San Borja to Terminal de buses La Serena
- Ave. Duration
- 7h 5m
- Frequency
- 5 times a day
- Estimated price
- $12–26
- Schedules at
- Condor Bus
- Semi Cama
- $12–20
- Cama
- $23–26
- Phone
- +56 512 669924
- [email protected]
- Website
- kupos.cl
Bus from Terminal San Borja to Terminal de buses La Serena
- Ave. Duration
- 6h
- Frequency
- Twice daily
- Estimated price
- $16–21
- Schedules at
- busesserenamar.cl
- Phone
- +56 57 226 9210
- [email protected]
- Website
- Ramos Cholele
Bus from Terminal San Borja to Terminal de buses La Serena
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Estimated price
- $13–45
- Schedules at
- Ramos Cholele
- Semi cama
- $13–18
- Salón cama
- $41–45
- Phone
- +56 2 3304 8632 / 2 2596 1100
- [email protected]
- Website
- Expreso Norte
Bus from Terminal San Borja to Terminal de buses La Serena
- Ave. Duration
- 6h 26m
- Frequency
- Once daily
- Estimated price
- $7–24
- Schedules at
- Expreso Norte
- [email protected]
- Website
- ciktur.cl
Bus from Terminal San Borja to Terminal de buses La Serena
- Ave. Duration
- 6h 50m
- Frequency
- 6 times a week
- Estimated price
- $27–40
- Schedules at
- kupos.cl
- Cama
- $30–40
- Semi Cama
- $27–35
- Phone
- +56 61 224 2313
- [email protected]
- Website
- Buses Fernández
Bus from Terminal Punta Arenas - Buses Fernandez to Terminal Rodoviario
- Ave. Duration
- 3h
- Frequency
- Every 3 hours
- Estimated price
- $10
- Schedules at
- Buses Fernández
- Phone
- 0810 122 1122
- [email protected]
- Website
- andesmar.com
Bus from Terminal de Ómnibus de Río Gallegos to Vicuña Mackenna
- Ave. Duration
- 34h 7m
- Frequency
- Once daily
- Estimated price
- $160–270
- Schedules at
- andesmar.com
- Semicama
- $160–200
- Cama
- $220–270
- Phone
- 0810-333-7575
- [email protected]
- Website
- viatac.com.ar
Bus from Vicuña Mackenna to Ediro San Luis
- Ave. Duration
- 2h 49m
- Frequency
- Once daily
- Estimated price
- $9–17
- Schedules at
- viatac.com.ar
- Book at
- viatac.com.ar
- Semi Bed
- $9–14
- Bed
- $11–17
Bus from Ediro San Luis to Terminal Mendoza
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $12–22
- Schedules at
- viatac.com.ar
- Book at
- viatac.com.ar
- Semi Bed
- $12–19
- Bed
- $14–22
- Phone
- 0810-222-5202
- [email protected]
- Website
- Nueva Chevallier
Bus from Ediro San Luis to Terminal Mendoza
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $13–25
- Website
- Nueva Chevallier
- Bed
- $17–25
- Semi Bed
- $13–20
- Phone
- 0800 122 2282
- [email protected]
- Website
- Cata International
Bus from Ediro San Luis to Terminal Mendoza
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $14–25
- Website
- Cata International
- Ejecutivo
- $17–25
- Semi Cama
- $14–20
- Ejecutivo Individual
- $19–25
Bus from Terminal Mendoza to Terminal de buses La Serena
- Ave. Duration
- 11h 45m
- Frequency
- Once a week
- Estimated price
- $35–91
- Website
- Cata International
- Ejecutivo
- $40–65
- Semi Cama
- $35–55
- Ejecutivo Individual
- $50–70
Bus from Bariloche Terminal to Terminal De Ómnibus San Juan
- Ave. Duration
- 23h
- Frequency
- Once daily
- Estimated price
- $70–140
- Website
- Cata International
- Ejecutivo
- $85–120
- Semi Cama
- $70–100
- Ejecutivo Individual
- $100–140
Bus from Terminal De Ómnibus San Juan to Terminal de buses La Serena
- Ave. Duration
- 14h 30m
- Frequency
- Once a week
- Estimated price
- $45–91
- Website
- Cata International
- Ejecutivo
- $50–75
- Semi Cama
- $45–65
- Ejecutivo Individual
- $65–85
- Phone
- 0800-222-6513
- [email protected]
- Website
- la20.com.ar
Bus from Ediro San Luis to Terminal Mendoza
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Estimated price
- $23–40
- Schedules at
- la20.com.ar
- Semicama
- $23–35
- Cama
- $28–40
- Phone
- +54 810 222 5202
- [email protected]
- Website
- atsj.com.ar
Bus from Ediro San Luis to Terminal Mendoza
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $13–23
- Schedules at
- atsj.com.ar
- Book at
- centraldepasajes.com.ar
- Bed
- $16–23
- Semi bed
- $13–19
- Phone
- +54 261 4690541
- [email protected]
- Website
- Central Argentino de Mendoza
Bus from Ediro San Luis to Terminal Mendoza
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Schedules at
- Central Argentino de Mendoza
- Phone
- 0810-333-7575
- [email protected]
- Website
- viabariloche.com.ar
Bus from Ediro San Luis to Terminal Mendoza
- Ave. Duration
- 3h 45m
- Frequency
- Once daily
- Estimated price
- $13–23
- Schedules at
- viabariloche.com.ar
- Book at
- viabariloche.com.ar
- Semi Cama
- $13–19
- Cama
- $16–23
- Phone
- +54 810 333 6744
- [email protected]
- Website
- Del Sur y Media Agua
Bus from Ediro San Luis to Terminal Mendoza
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Schedules at
- Del Sur y Media Agua
- Phone
- 0810-222-5202
- [email protected]
- Website
- atsj.com.ar
Bus from Ediro San Luis to Terminal Mendoza
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $21–30
- Schedules at
- atsj.com.ar
- Book at
- atsj.com.ar
- Bed
- $21–30
- Semi Bed
- $21–26
- Phone
- +56 9 8521 3620
- [email protected]
- Website
- Navimag
Ferry from Puerto Natales to Puerto Montt
- Ave. Duration
- 3d 11h
- Frequency
- Twice a week
- Estimated price
- $330–890
- Website
- Navimag
- Cabin AA
- $700
- Cabin A
- $600
- Cabin CC
- $330
- Premium Suite
- $890
Want to know more about travelling around the world?
Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Is ride-sharing platform BlaBlaCar right for you?, How to get from London City Airport into central London, and Travelling Croatia’s Dalmatian Coast by boat, bus, car and train - to help you get the most out of your next trip.
Booking & Getting There
There are 994+ hotels available in La Serena.
































































