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How to get fromQuad Cities to St. Louisby plane, bus, train, bus (Greyhound), car, or bus (Flixbus)

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There are 7 ways to get from Quad Cities to St. Louis by plane, bus, train, bus (Greyhound), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Range Regional Airport

    best
    1. Fly from Range Regional Airport (HIB) to Lambert–St. Louis International Airport (STL)plane plane HIB - STL
    5h 6m
    $166–627

  2. Drive 716.5 mi

    cheapest
    1. Drive from Quad Cities to St. Louiscar car 716.5 mi
    12h 44m
    $131–189

  3. Bus, train

    1. Take the bus from Virginia to Duluthbus bus
    2. Take the bus from Duluth to St. Paulbus bus
    3. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to St. Louistrain train
    18h 46m
    $294–569

  4. Bus

    1. Take the bus from Virginia to Duluthbus bus
    2. Take the bus from Duluth to Minneapolisbus bus
    3. Take the bus from Minneapolis to Des Moinesbus bus
    4. Take the bus from Des Moines to St Louis Bus Stationbus bus
    20h 3m
    $209–324

  5. Drive to International Falls, fly

    1. Drive from Quad Cities to International Falls (INL)car car
    2. Fly from International Falls (INL) to Lambert–St. Louis International Airport (STL)plane plane INL - STL
    6h 20m
    $131–628

  6. Bus to Duluth International Airport, fly

    1. Take the bus from Virginia to Duluthbus bus
    2. Fly from Duluth International Airport (DLH) to Lambert–St. Louis International Airport (STL)plane plane DLH - STL
    8h 29m
    $138–604

  7. Bus via Chicago

    1. Take the bus from Virginia to Duluthbus bus
    2. Take the bus from Duluth, MN to U of MN Campus - Minneapolisbus bus
    3. Take the bus from U of MN Campus to Madison, WI-Lake St.bus bus
    4. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    5. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    22h 29m
    $205–329

Range Regional Airport (HIB) to Lambert–St. Louis International Airport (STL) flights

Calendar19Weekly Planes
Duration5h 21mAverage Duration
Ticket$104Cheapest Price
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Questions & Answers

Map of how to get from Quad Cities to St. Louis.ExpandLaunch map view
  • Distance: 646.7 mi
  • Duration: 5h 6m

What companies run services between Quad Cities, MN, USA and St. Louis, MO, USA?

Delta flies from Range Regional Airport (HIB) to Lambert–St. Louis International Airport (STL) 3 times a day. Alternatively, you can take a vehicle from Quad Cities to St Louis Bus Station via Virginia, Duluth, Minneapolis, and Des Moines in around 20h 3m.

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