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How to get fromQuad Cities to St. Louisby plane, bus, train, bus (Greyhound), car, or bus (Flixbus)

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There are 7 ways to get from Quad Cities to St. Louis by plane, bus, train, bus (Greyhound), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Range Regional Airport

    best
    1. Fly from Range Regional Airport (HIB) to Lambert–St. Louis International Airport (STL)plane plane HIB - STL
    5h 6m
    $161–627

  2. Drive to International Falls, fly

    cheapest
    1. Drive from Quad Cities to International Falls (INL)car car
    2. Fly from International Falls (INL) to Lambert–St. Louis International Airport (STL)plane plane INL - STL
    6h 20m
    $121–578

  3. Bus, train

    1. Take the bus from Virginia to Duluthbus bus
    2. Take the bus from Duluth to St. Paulbus bus
    3. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to St. Louistrain train
    19h 1m
    $274–549

  4. Bus

    1. Take the bus from Virginia to Duluthbus bus
    2. Take the bus from Duluth to St. Paulbus bus
    3. Take the bus from Saint Paul Union Depot to Des Moinesbus bus
    4. Take the bus from Des Moines to St Louis Bus Stationbus bus
    20h 33m
    $169–299

  5. Drive 716.5 mi

    1. Drive from Quad Cities to St. Louiscar car 716.5 mi
    12h 44m
    $131–189

  6. Bus to Duluth International Airport, fly

    1. Take the bus from Virginia to Duluthbus bus
    2. Fly from Duluth International Airport (DLH) to Lambert–St. Louis International Airport (STL)plane plane DLH - STL
    8h 49m
    $128–604

  7. Bus via Milwaukee Airport (MKE)

    1. Take the bus from Virginia to Duluthbus bus
    2. Take the bus from Duluth to St. Paulbus bus
    3. Take the bus from Saint Paul Union Depot to Milwaukee Mitchell Airportbus bus
    4. Take the bus from Milwaukee Mitchell Airport to Chicago Bus Stationbus bus
    5. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    22h 48m
    $181–289

Range Regional Airport (HIB) to Lambert–St. Louis International Airport (STL) flights

Calendar19Weekly Planes
Duration5h 21mAverage Duration
Ticket$96Cheapest Price
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Questions & Answers

Map of how to get from Quad Cities to St. Louis.ExpandLaunch map view
  • Distance: 646.7 mi
  • Duration: 5h 6m

What companies run services between Quad Cities, MN, USA and St. Louis, MO, USA?

Delta flies from Range Regional Airport (HIB) to Lambert–St. Louis International Airport (STL) 3 times a day. Alternatively, you can take a vehicle from Quad Cities to St Louis Bus Station via Virginia, Duluth, Saint Paul Union Depot, and Des Moines in around 20h 33m.

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