There are 12 ways to get from Quakertown to Buffalo by bus, train, car, plane, bus (Greyhound), or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Quakertown Trans-Bridge stop to Port Authority Bus Terminalbus Eastbound from Doylestown
- Take the bus from New York to Buffalobus Adt N816 / ...
11h 58m$131–357Drive 308.6 mi
cheapest- Drive from Quakertown to Buffalocar 308.6 mi
6h 26m$57–82Bus, train
- Take the bus from Quakertown Trans-Bridge stop to Port Authority Bus Terminalbus Eastbound from Doylestown
- Take the train from New York Penn Station to Buffalotrain VIA Rail
12h 36m$191–367Bus to Laguardia Airport, fly to Buffalo Niagara International Airport
- Take the bus from Quakertown Trans-Bridge stop to Port Authority Bus Terminalbus
- Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane LGA - BUF
7h 20m$164–708Bus via Scranton (Greyhound)
- Take the bus from Doylestown SEPTA Station to Scranton Bus Stationbus Greyhound US0340s
- Take the bus from Scranton Bus Station to Buffalobus Greyhound US0205 / ...
12h 20m$106–169Bus, train via New York
- Take the bus from Quakertown, PA - 60 4th St to New York, NYbus Doylestown-Flemington Eastbound
- Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain Empire Service / ...
12h 51m$191–346Train
- Take the train from Doylestown to Jefferson Stationtrain Lan
- Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain
13h 43m$201–935Train to Philadelphia International Airport, fly to Buffalo Niagara International Airport
- Take the train from Doylestown to Suburban Stationtrain
- Fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF)plane PHL - BUF
6h 57m$156–693Bus to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport
- Take the bus from Quakertown Trans-Bridge stop to Port Authority Bus Terminalbus
- Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane JFK - BUF
7h 27m$155–564Train to Philadelphia International Airport, fly to Rochester, bus
- Take the train from Doylestown to Suburban Stationtrain
- Fly from Philadelphia International Airport (PHL) to Rochester (ROC)plane PHL - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
8h 19m$199–857Train, train to Baltimore-Washington International Airport, fly to Buffalo Niagara International Airport
- Take the train from Doylestown to Jefferson Stationtrain
- Take the train from 30th Street Station to BWI Thurgood Marshalltrain
- Fly from Baltimore-Washington International Airport (BWI) to Buffalo Niagara International Airport (BUF)plane BWI - BUF
7h 53m$165–1,293Train, train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport
- Take the train from Doylestown to Jefferson Stationtrain
- Take the train from 30th Street Station to Newark Liberty International Airporttrain
- Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane EWR - BUF
8h 21m$153–603
Quakertown to Buffalo by bus
Questions & Answers
The cheapest way to get from Quakertown to Buffalo is to drive which costs $55 - $85 and takes 6h 26m.
The fastest way to get from Quakertown to Buffalo is to drive which takes 6h 26m and costs $55 - $85.
No, there is no direct bus from Quakertown to Buffalo. However, there are services departing from Quakertown Trans-Bridge stop and arriving at Buffalo via New York. The journey, including transfers, takes approximately 11h 58m.
No, there is no direct train from Quakertown to Buffalo. However, there are services departing from Doylestown and arriving at Buffalo via 11th St, 30th Street Station and Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 13h 43m.
The distance between Quakertown and Buffalo is 613 miles. The road distance is 310.4 miles.
The best way to get from Quakertown to Buffalo without a car is to bus which takes 11h 58m and costs $130 - $360.
It takes approximately 11h 58m to get from Quakertown to Buffalo, including transfers.
Quakertown to Buffalo bus services, operated by Trans-bridge Lines, depart from Quakertown Trans-Bridge stop station.
Quakertown to Buffalo train services, operated by SEPTA, depart from Doylestown station.
The best way to get from Quakertown to Buffalo is to bus which takes 11h 58m and costs $130 - $360. Alternatively, you can train, which costs $200 - $950 and takes 13h 43m.
What companies run services between Quakertown, PA, USA and Buffalo, NY, USA?
You can take a bus from Quakertown Trans-Bridge stop to Buffalo via Port Authority Bus Terminal and New York in around 11h 58m. Alternatively, you can take a bus from Quakertown, PA - 60 4th St to Buffalo via Doylestown, PA - Septa Train Station Bus Shelter - 130 S Clinton Ave, Doylestown, Jefferson Station, 11th St, Drexel Station at 30th St, 30th Street Station, and Ny Moynihan Train Hall At Penn Station in around 13h 43m.
- Website
- aa.com
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $85–600
Flights from Laguardia Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $110–650
Flights from Philadelphia International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $90–600
Flights from Philadelphia International Airport to Rochester
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $110–750
- Website
- united.com
Flights from Laguardia Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 48m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–650
Flights from Philadelphia International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $100–650
Flights from Philadelphia International Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 44m
- When
- Every day
- Estimated price
- $140–850
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $65–460
Flights from Newark Liberty International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $90–550
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $75–550
- Website
- delta.com
Flights from Laguardia Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $85–600
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $65–440
- Website
- jetblue.com
Flights from John F. Kennedy International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $65–440
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from New York Penn Station to Buffalo
- Ave. Duration
- 8h 24m
- Frequency
- Once daily
- Estimated price
- $120–290
- Website
- VIA Rail
- Escape
- $120–260
- Business
- $160–280
- Business Plus
- $170–290
- Economy
- $130–270
- Economy Plus
- $140–280
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Buffalo
- Ave. Duration
- 8h 35m
- Frequency
- 3 times a day
- Estimated price
- $120–270
- Website
- Amtrak
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 24m
- Frequency
- Every 30 minutes
- Estimated price
- $25–55
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Buffalo
- Ave. Duration
- 8h 35m
- Frequency
- 3 times a day
- Estimated price
- $120–270
- Website
- Amtrak
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- $29–65
- Website
- Amtrak
Train from 30th Street Station to Newark Liberty International Airport
- Ave. Duration
- 56 min
- Frequency
- Every 3 hours
- Estimated price
- $22–50
- Website
- Amtrak
- Phone
- +1 215-580-7800
- Website
- SEPTA
Train from Doylestown to Jefferson Station
- Ave. Duration
- 1h 19m
- Frequency
- Hourly
- Estimated price
- $3
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Train from Doylestown to Suburban Station
- Ave. Duration
- 1h 24m
- Frequency
- Hourly
- Estimated price
- $3
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Train from Doylestown to Suburban Station
- Ave. Duration
- 1h 24m
- Frequency
- Hourly
- Estimated price
- $3
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Train from Doylestown to Jefferson Station
- Ave. Duration
- 1h 19m
- Frequency
- Hourly
- Estimated price
- $3
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Train from Doylestown to Jefferson Station
- Ave. Duration
- 1h 19m
- Frequency
- Hourly
- Estimated price
- $3
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- $20–600
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $20–460
- First Class
- $130–600
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 22m
- Frequency
- 5 times a day
- Estimated price
- $24–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $24–460
- First Class
- $140–650
- Phone
- +1 610-868-6001
- [email protected]
- Website
- Trans-Bridge Lines
Bus from Quakertown Trans-Bridge stop to Port Authority Bus Terminal
- Ave. Duration
- 2h 58m
- Frequency
- 4 times a week
- Estimated price
- $70–80
- Website
- Trans-Bridge Lines
- Schedules at
- Trans-Bridge Lines Schedules
- Adult
- $70–80
Bus from Quakertown Trans-Bridge stop to Port Authority Bus Terminal
- Ave. Duration
- 2h 58m
- Frequency
- 4 times a week
- Estimated price
- $70–80
- Website
- Trans-Bridge Lines
- Schedules at
- Trans-Bridge Lines Schedules
- Adult
- $70–80
Bus from Quakertown Trans-Bridge stop to Port Authority Bus Terminal
- Ave. Duration
- 2h 58m
- Frequency
- 4 times a week
- Estimated price
- $70–80
- Website
- Trans-Bridge Lines
- Schedules at
- Trans-Bridge Lines Schedules
- Adult
- $70–80
Bus from Quakertown, PA - 60 4th St to New York, NY
- Ave. Duration
- 3h 5m
- Frequency
- 4 times a week
- Estimated price
- $70–80
- Schedules at
- transbridgelines.com
- Adult
- $70–80
Bus from Quakertown Trans-Bridge stop to Port Authority Bus Terminal
- Ave. Duration
- 2h 58m
- Frequency
- 4 times a week
- Estimated price
- $70–80
- Website
- Trans-Bridge Lines
- Schedules at
- Trans-Bridge Lines Schedules
- Adult
- $70–80
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Doylestown SEPTA Station to Scranton Bus Station
- Ave. Duration
- 4h 15m
- Frequency
- Once daily
- Estimated price
- $16–35
- Website
- Greyhound
Bus from Scranton Bus Station to Buffalo
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $35–75
- Website
- Greyhound
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- 5 times a day
- Estimated price
- $10–20
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $10–17
- Schedules at
- Flixbus USA
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More Questions & Answers
Quakertown to Buffalo bus services, operated by Trans-bridge Lines, arrive at Port Authority Bus Terminal station.
Quakertown to Buffalo train services, operated by SEPTA, arrive at Jefferson Station.
Yes, the driving distance between Quakertown to Buffalo is 310 miles. It takes approximately 6h 26m to drive from Quakertown to Buffalo.
There are 264+ hotels available in Buffalo.

























