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How to get fromQuakertown to Buffaloby bus, train, car, plane, bus (Greyhound), or train (Amtrak)

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There are 11 ways to get from Quakertown to Buffalo by bus, train, car, plane, bus (Greyhound), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Quakertown, PA - 60 4th St to New York, NYbus bus Doylestown-Flemington Eastbound
    2. Take the bus from New York to Buffalobus bus Adt N816-D / ...
    12h 5m
    $131–356

  2. Drive  308.6 mi

    cheapest
    1. Drive from Quakertown to Buffalocar car 308.6 mi
    6h 26m
    $57–82

  3. Bus, train

    1. Take the bus from Quakertown, PA - 60 4th St to New York, NYbus bus Doylestown-Flemington Eastbound
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train Empire Service / ...
    12h 51m
    $311–456

  4. Bus to Laguardia Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Quakertown, PA - 60 4th St to New York, NYbus bus
    2. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    7h 28m
    $169–757

  5. Bus via Scranton (Greyhound)

    1. Take the bus from Doylestown SEPTA Station to Scranton Bus Stationbus bus Greyhound US0340s
    2. Take the bus from Scranton Bus Station to Buffalobus bus Greyhound US0205 / ...
    12h 20m
    $114–159

  6. Train

    1. Take the train from Doylestown to Jefferson Stationtrain train Lan
    2. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train
    13h 46m
    $320–1,048

  7. Train to Philadelphia International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Doylestown to Suburban Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Buffalo Niagara International Airport (BUF)plane plane PHL - BUF
    6h 59m
    $150–696

  8. Bus to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Quakertown, PA - 60 4th St to New York, NYbus bus
    2. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane plane JFK - BUF
    7h 41m
    $155–553

  9. Train to Philadelphia International Airport, fly to Rochester, bus

    1. Take the train from Doylestown to Suburban Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Rochester (ROC)plane plane PHL - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    8h 20m
    $199–909

  10. Train, train to Baltimore-Washington International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Doylestown to Jefferson Stationtrain train
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Buffalo Niagara International Airport (BUF)plane plane BWI - BUF
    8h 1m
    $169–1,296

  11. Train, train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the train from Doylestown to Jefferson Stationtrain train
    2. Take the train from 30th Street Station to Newark Liberty International Airporttrain train
    3. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    8h 22m
    $175–656

Quakertown to Buffalo by bus

Calendar4Weekly Buses
Duration12h 5mAverage Duration
Ticket$131Cheapest Price
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Comparing Your Travel Options

Map of how to get from Quakertown to Buffalo.ExpandLaunch map view
  • Distance: 607.7 mi
  • Duration: 12h 5m

What companies run services between Quakertown, PA, USA and Buffalo, NY, USA?

You can take a bus from Quakertown, PA - 60 4th St to Buffalo via New York, NY and New York in around 12h 5m. Alternatively, you can take a bus from Quakertown, PA - 60 4th St to Buffalo via Doylestown, PA - Septa Train Station Bus Shelter - 130 S Clinton Ave, Doylestown, Jefferson Station, 11th St, Drexel Station at 30th St, 30th Street Station, and Ny Moynihan Train Hall At Penn Station in around 13h 46m.

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