There are 4 ways to get from Quito to Panama City by car, plane, bus, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Car, fly to Tocumen International Airport
best- Drive from Quito to Quito Airportcar
- Fly from Mariscal Sucre International Airport (UIO) to Tocumen International Airport (PTY)plane UIO - PTY
5h 9m$353–663Car, fly to Panama Pacific International Airport
cheapest- Drive from Quito to Quito Airportcar
- Fly from Mariscal Sucre International Airport (UIO) to Panama Pacific International Airport (BLB)plane UIO - BLB
3h 59m$272–896Bus, ferry, drive via Cali
- Take the bus from Terminal Terrestre Quitumbe to Rumichacabus
- Take the bus from Ipiales to Terminal de Transporte Calibus
- Take the bus from Terminal de Transporte Cali to Terminal del Nortebus
- Take the bus from Terminal del Norte to Terminal de Transporte de Cartagenabus
- Take the ferry from Cartagena to Portobeloferry
- Drive from Portobelo to Panama Citycar
7d 17h$836–910Bus, ferry, drive
- Take the bus from Terminal Terrestre Quitumbe to Rumichacabus
- Take the bus from Terminales de Transportes de Ipiales to Terminal Salitrebus
- Take the bus from Terminal Salitre to Terminal de Transporte de Cartagenabus
- Take the ferry from Cartagena to Portobeloferry
- Drive from Portobelo to Panama Citycar
8d 4h$862–935
Mariscal Sucre International Airport (UIO) to Tocumen International Airport (PTY) flights
Comparing Your Travel Options
The cheapest way to get from Quito to Panama City is to car and fly which costs $350 - $700 and takes 5h 9m.
The fastest way to get from Quito to Panama City is to car and fly which takes 3h 59m and costs $270 - $900.
The distance between Quito and Panama City is 1093 km.
It takes approximately 5h 9m to get from Quito to Panama City, including transfers.
There are 893+ hotels available in Panama City.
What companies run services between Quito, Ecuador and Panama City, Panama?
There is no direct connection from Quito to Panama City. However, you can drive to Quito Airport, walk to Mariscal Sucre International Airport (UIO) airport, fly to Tocumen International Airport (PTY), walk to Aeropuerto Internacional de Tocumen, then take the shuttle to Amador. Alternatively, you can take a bus from Terminal Terrestre Quitumbe to Panama City via Rumichaca, Terminal Ipiales, Ipiales, Terminal de Transporte Cali, Terminal del Norte, Terminal de Transporte de Cartagena, Cartagena, and Portobelo in around 7d 17h.
- Website
- copaair.com
Flights from Mariscal Sucre International Airport to Tocumen International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $60–340
- Website
- klm.com
Flights from Mariscal Sucre International Airport to Tocumen International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $60–340
Flights from Mariscal Sucre International Airport to Tocumen International Airport via Guayaquil
- Ave. Duration
- 4h 35m
- When
- Tuesday to Sunday
- Estimated price
- $75–400
- Website
- avianca.com
Flights from Mariscal Sucre International Airport to Tocumen International Airport via Bogota
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $290–650
Flights from Mariscal Sucre International Airport to Panama Pacific International Airport
- Ave. Duration
- 1h 30m
- When
- Thursday and Sunday
- Estimated price
- $230–850
- Phone
- +51 9 6788 4526
- [email protected]
- Website
- Lineas De Los Andes
Bus from Terminal Terrestre Quitumbe to Rumichaca
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- $30–40
- Website
- Lineas De Los Andes
Bus from Terminal Terrestre Quitumbe to Rumichaca
- Ave. Duration
- 2h 54m
- Frequency
- Once daily
- Estimated price
- $30–40
- Website
- Lineas De Los Andes
- Phone
- +57 601 4249090
- [email protected]
- Website
- bolivariano.com.co
Bus from Ipiales to Terminal de Transporte Cali
- Ave. Duration
- 12h
- Frequency
- Every 3 hours
- Estimated price
- $25–45
- Schedules at
- bolivariano.com.co
- Book at
- bolivariano.com.co
Bus from Terminales de Transportes de Ipiales to Terminal Salitre
- Ave. Duration
- 22h
- Frequency
- Every 4 hours
- Estimated price
- $55–80
- Schedules at
- bolivariano.com.co
- Book at
- bolivariano.com.co
- Phone
- +57 314 8300867
- [email protected]
- Website
- cootranar.com
Bus from Ipiales to Terminal de Transporte Cali
- Ave. Duration
- 10h
- Frequency
- 3 times a day
- Estimated price
- $34
- Schedules at
- cootranar.com
- Book at
- redbus.co
- Phone
- +57 311 273 0419
- [email protected]
- Website
- expresopalmira.com.co
Bus from Terminal de Transporte Cali to Terminal del Norte
- Ave. Duration
- 9h
- Frequency
- 3 times a day
- Estimated price
- $29–50
- Schedules at
- expresopalmira.com.co
- Book at
- expresopalmira.com.co
- Phone
- 01 800 051 8001
- [email protected]
- Website
- expresobrasilia.com
Bus from Terminal del Norte to Terminal de Transporte de Cartagena
- Ave. Duration
- 11h 39m
- Frequency
- Every 4 hours
- Estimated price
- $35–55
- Schedules at
- expresobrasilia.com
- Book at
- expresobrasilia.com
- Preferencial de Lujo
- $35–55
- Phone
- +57 604 444 8888
- [email protected]
- Website
- rapidoochoa.com.co
Bus from Terminal del Norte to Terminal de Transporte de Cartagena
- Ave. Duration
- 15h 40m
- Frequency
- 5 times a day
- Estimated price
- $35–55
- Schedules at
- rapidoochoa.com.co
- Book at
- rapidoochoa.com.co
- Phone
- +57 601 424 9090
- [email protected]
- Website
- continentalbus.com.co
Bus from Terminales de Transportes de Ipiales to Terminal Salitre
- Ave. Duration
- 22h
- Frequency
- Every 4 hours
- Estimated price
- $58
- Schedules at
- continentalbus.com.co
- Phone
- +57 323 563 9139
- [email protected]
- Website
- copetran.com
Bus from Terminal Salitre to Terminal de Transporte de Cartagena
- Ave. Duration
- 23h
- Frequency
- Every 3 hours
- Estimated price
- $60–85
- Schedules at
- copetran.com
- Book at
- copetran.com
- Road
- $60–85
- Phone
- +57 310 7883333
- [email protected]
- Website
- concordeoficial.com
Bus from Terminal Salitre to Terminal de Transporte de Cartagena
- Ave. Duration
- 24h 45m
- Frequency
- 3 times a day
- Estimated price
- $65–95
- Schedules at
- concordeoficial.com
- Book at
- concordeoficial.com
- Phone
- +57 310 704 0425
- [email protected]
- Website
- Blue Sailing
Ferry from Cartagena to Portobelo
- Ave. Duration
- 6d
- Frequency
- On demand
- Estimated price
- $700
- Website
- Blue Sailing
Ferry from Cartagena to Portobelo
- Ave. Duration
- 6d
- Frequency
- On demand
- Estimated price
- $700
- Website
- Blue Sailing
- Phone
- +593 98 414 6312
- [email protected]
- Website
- Fantasy Travel Ecuador
Car from Quito to Quito Airport
- Ave. Duration
- 20 min
- Frequency
- On demand
- Estimated price
- $25
- Schedules at
- Fantasy Travel Ecuador
Car from Quito to Quito Airport
- Ave. Duration
- 20 min
- Frequency
- On demand
- Estimated price
- $25
- Schedules at
- Fantasy Travel Ecuador
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