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How to get fromQuito to Santa Cruzby car, plane, bus, or shuttle

Find Transport to Santa Cruz

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There are 5 ways to get from Quito to Santa Cruz by car, plane, bus, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Car, fly

    best
    1. Drive from Quito to Quito Airportcar car
    2. Fly from Mariscal Sucre International Airport (UIO) to Viru Viru International Airport (VVI)plane plane UIO - VVI
    9h 35m
    $486–776

  2. Bus via Lima

    cheapest
    1. Take the bus from Terminal Terrestre Quitumbe to Lima Plaza Nortebus bus
    2. Take the bus from Lima - Terminal Arriola to La Pazbus bus
    3. Take the bus from La Paz to Santa Cruzbus bus
    3d 13h
    $165–704

  3. Bus

    1. Take the bus from Terminal Terrestre Quitumbe to Gran Terminal Terrestre Plaza Nortebus bus
    2. Take the bus from Oltursa Lima Terminal to La Pazbus bus
    3. Take the bus from La Paz to Santa Cruzbus bus
    3d 2h
    $240–322

  4. Drive  4,012.2 km

    1. Drive from Quito to Santa Cruz de la Sierracar car 4,012.2 km
    2d 9h
    $228–329

  5. Bus, Tour

    1. Take the bus from Terminal Terrestre Quitumbe to Lima Plaza Nortebus bus
    2. Take the bus from Terminal Ronco to Punobus bus
    3. Take a shuttle bus from Puno to La Pazshuttle bus
    4. Take the bus from La Paz to Santa Cruzbus bus
    3d 17h
    $170–294

Mariscal Sucre International Airport (UIO) to Viru Viru International Airport (VVI) flights

Calendar34Weekly Planes
Duration7h 55mAverage Duration
Ticket$192Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Quito to Santa Cruz.ExpandLaunch map view
  • Distance: 2,623.4 km
  • Duration: 9h 35m

What companies run services between Quito, Ecuador and Santa Cruz, Bolivia?

You can take a bus from Terminal Terrestre Quitumbe to Santa Cruz de la Sierra via Gran Terminal Terrestre Plaza Norte, Oltursa Lima Terminal, La Paz, and Santa Cruz in around 3d 2h.

Airlines
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Rome2Rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including How to get from Heathrow Airport into central London, Travelling to the UK: What do I need to know?, and How to get from Florence to Rome - to help you get the most out of your next trip.

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