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How to get fromRüsselsheim am Main to Brusselsby train, bus, car, or plane

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There are 6 ways to get from Rüsselsheim am Main to Brussels by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Frankfurt to Brussels-Nordtrain train 79
    4h 7m
    €69–311

  2. Bus

    cheapest
    1. Take the bus from Mainz central train station to Brussels-North train stationbus bus N1310
    7h 18m
    €34–60

  3. Drive 384.5 km

    1. Drive from Rüsselsheim am Main to Brusselscar car 384.5 km
    3h 36m
    €59–85

  4. Fly to Brussels Airport

    1. Fly from Frankfurt (FRA) to Brussels Airport (BRU)plane plane FRA - BRU
    3h 29m
    €81–226

  5. Bus, train

    1. Take the bus from Wiesbaden Hauptbahnhof to Koblenz Hauptbahnhof Westbus bus 10X
    2. Take the train from Koblenz Hbf to Bruxelles-Nordtrain train Nj
    9h

  6. Fly to Amsterdam Airport Schiphol, train

    1. Fly from Frankfurt (FRA) to Amsterdam Airport Schiphol (AMS)plane plane FRA - AMS
    2. Take the train from Schiphol Airport to Brussel-Zuid / Bruxelles-Miditrain train
    5h 23m
    €179–391

Rüsselsheim am Main to Brussels by train

Calendar61Weekly Trains
Duration4h 7mAverage Duration
Ticket€69Cheapest Price
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Questions & Answers

Map of how to get from Rüsselsheim am Main to Brussels.ExpandLaunch map view
  • Distance: 400.3 km
  • Duration: 4h 7m

What companies run services between Rüsselsheim am Main, Germany and Brussels, Belgium?

Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Brussels-Nord every 4 hours. Tickets cost €70–300 and the journey takes 2h 55m. Belgian Railways (NMBS/SNCB) also services this route 4 times a week. Alternatively, FlixBus operates a bus from Mainz central train station to Brussels-North train station once daily. Tickets cost €30–55 and the journey takes 5h 45m.

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