There are 7 ways to get from Raleigh to La Crosse by plane, train (Amtrak), bus (Greyhound, Flixbus), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Raleigh-Durham International Airport to La Crosse
best- Fly from Raleigh-Durham International Airport (RDU) to La Crosse (LSE)plane RDU - LSE
6h 51m$112–496Train (Amtrak)
- Take the train from Raleigh Union Station to Chicago Union Stationtrain Floridian
- Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain Empire Builder / ...
30h 27m$742–1,149Bus
- Take the bus from Raleigh Bus Station to Washington Union Stationbus
- Take the bus from Washington Union Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus
- Take the bus from Milwaukee to La Crossebus
31h 15m$224–360Drive 1,070 mi
- Drive from Raleigh to La Crossecar 1,070 mi
18h 36m$196–283Train to Piedmont Triad International Airport, fly to La Crosse
- Take the train from Raleigh Union Station to Greensborotrain
- Fly from Piedmont Triad International Airport (GSO) to La Crosse (LSE)plane GSO - LSE
8h 25m$194–681Fly Raleigh-Durham International Airport to Minneapolis–Saint Paul International Airport, train
- Fly from Raleigh-Durham International Airport (RDU) to Minneapolis–Saint Paul International Airport (MSP)plane RDU - MSP
- Take the train from St. Paul-Minneapolis to La Crosse Amtrak Stationtrain
8h 52m$194–516Train, bus
- Take the train from Raleigh Union Station to Chicago Union Stationtrain
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus
- Take the bus from Madison to La Crossebus
32h 5m$652–1,019
Raleigh to La Crosse by train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Raleigh to La Crosse is to drive which costs $190 - $290 and takes 18h 36m.
The fastest way to get from Raleigh to La Crosse is to fly which takes 6h 51m and costs $110 - $500.
No, there is no direct bus from Raleigh station to La Crosse. However, there are services departing from GoRaleigh Station and arriving at La Crosse via Raleigh Bus Station, Washington Union Station, Chicago Bus Station and Milwaukee. The journey, including transfers, takes approximately 31h 15m.
No, there is no direct train from Raleigh station to La Crosse station. However, there are services departing from Raleigh Union Station and arriving at La Crosse Amtrak Station via Chicago Union Station. The journey, including transfers, takes approximately 30h 27m.
The distance between Raleigh and La Crosse is 886 miles. The road distance is 1076.3 miles.
The best way to get from Raleigh to La Crosse without a car is to train which takes 30h 27m and costs $700 - $1,200.
It takes approximately 6h 51m to get from Raleigh to La Crosse, including transfers.
Raleigh to La Crosse bus services, operated by Greyhound USA, depart from Raleigh Bus Station.
Raleigh to La Crosse train services, operated by Amtrak, depart from Raleigh Union Station.
The best way to get from Raleigh to La Crosse is to fly which takes 6h 51m and costs $110 - $500. Alternatively, you can train, which costs $700 - $1,200 and takes 30h 27m, you could also bus, which costs $220 - $360 and takes 31h 15m.
What companies run services between Raleigh, NC, USA and La Crosse, WI, USA?
American Airlines and United Airlines fly from Raleigh-Durham International Airport (RDU) to La Crosse (LSE) every 4 hours. Alternatively, you can take a train from Raleigh Union Station to La Crosse Amtrak Station via Chicago Union Station in around 30h 27m.
- Website
- aa.com
Flights from Raleigh-Durham International Airport to La Crosse via Chicago O'Hare
- Ave. Duration
- 6h 38m
- When
- Every day
- Estimated price
- $90–470
Flights from Piedmont Triad International Airport to La Crosse via Chicago O'Hare
- Ave. Duration
- 6h 8m
- When
- Every day
- Estimated price
- $100–550
Flights from Piedmont Triad International Airport to La Crosse via Charlotte, Chicago O'Hare
- Ave. Duration
- 8h 35m
- When
- Every day
- Estimated price
- $100–550
Flights from Piedmont Triad International Airport to La Crosse via New York La Guardia, Chicago O'Hare
- Ave. Duration
- 9h 46m
- When
- Every day
- Estimated price
- $140–700
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Minneapolis–Saint Paul International Airport via Chicago Midway
- Ave. Duration
- 4h 21m
- When
- Sunday, Tuesday, Wednesday, and Saturday
- Estimated price
- $120–650
Flights from Raleigh-Durham International Airport to Minneapolis–Saint Paul International Airport via St. Louis
- Ave. Duration
- 4h 41m
- When
- Saturday, Tuesday, Wednesday, and Sunday
- Estimated price
- $130–650
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 2h 50m
- When
- Every day
- Estimated price
- $120–650
Flights from Raleigh-Durham International Airport to Minneapolis–Saint Paul International Airport via Detroit
- Ave. Duration
- 4h 48m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
- Website
- suncountry.com
Flights from Raleigh-Durham International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 2h 43m
- When
- Monday, Friday, and Sunday
- Estimated price
- $120–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Raleigh Union Station to Chicago Union Station
- Ave. Duration
- 24h 28m
- Frequency
- Once daily
- Estimated price
- $550–950
- Website
- Amtrak
Train from Chicago Union Station to La Crosse Amtrak Station
- Ave. Duration
- 4h 59m
- Frequency
- 3 times a day
- Estimated price
- $150–240
- Website
- Amtrak
Train from Raleigh Union Station to Greensboro
- Ave. Duration
- 1h 33m
- Frequency
- 5 times a day
- Estimated price
- $40–70
- Website
- Amtrak
Train from St. Paul-Minneapolis to La Crosse Amtrak Station
- Ave. Duration
- 2h 47m
- Frequency
- 3 times a day
- Estimated price
- $70–110
- Website
- Amtrak
Train from Raleigh Union Station to Chicago Union Station
- Ave. Duration
- 24h 28m
- Frequency
- Once daily
- Estimated price
- $550–950
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Raleigh Bus Station to Washington Union Station
- Ave. Duration
- 4h 35m
- Frequency
- Every 4 hours
- Estimated price
- $45–70
- Website
- Greyhound
Bus from Washington Union Station to Chicago Bus Station
- Ave. Duration
- 17h 10m
- Frequency
- Twice daily
- Estimated price
- $120–190
- Website
- Greyhound
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $15–24
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Raleigh Bus Station to Washington Union Station
- Ave. Duration
- 5h 15m
- Frequency
- Twice daily
- Estimated price
- $40–60
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- $13–21
- Schedules at
- Flixbus USA
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Milwaukee to La Crosse
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $50–75
- Book at
- Jefferson Lines
- Adult
- $50–75
Bus from Madison to La Crosse
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Book at
- Jefferson Lines
- Adult
- $35–55
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- Rockland Coaches
Bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 3h 40m
- Frequency
- Hourly
- Estimated price
- $25–55
- Schedules at
- Rockland Coaches
- Adult
- $25–55
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
Raleigh to La Crosse bus services, operated by Greyhound USA, arrive at Washington Union Station.
La Crosse is 1h behind Raleigh. It is currently 6:01 PM in Raleigh and 5:01 PM in La Crosse.
Raleigh to La Crosse train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Raleigh to La Crosse is 1076 miles. It takes approximately 18h 36m to drive from Raleigh to La Crosse.
Book your Raleigh to La Crosse train tickets online with Omio.
There are 47+ hotels available in La Crosse.









