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How to get fromRaleigh to Saint Charlesby plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or train

Find Transport to Saint Charles

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There are 6 ways to get from Raleigh to Saint Charles by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Raleigh-Durham International Airport

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL)plane plane RDU - STL
    4h 49m
    $556–1,106

  2. Bus to Fayetteville Municipal Airport, fly

    cheapest
    1. Take the bus from Raleigh Bus Station to Fayetteville Bus Stationbus bus
    2. Fly from Fayetteville Municipal Airport (FAY) to Lambert–St. Louis International Airport (STL)plane plane FAY - STL
    7h 17m
    $125–593

  3. Bus

    1. Take the bus from Raleigh Bus Station to Atlanta Bus Stationbus bus Greyhound US0670 / ...
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    23h 58m
    $138–293

  4. Train (Amtrak)

    1. Take the train from Raleigh Union Station to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    31h 39m
    $364–801

  5. Drive  800.9 mi

    1. Drive from Raleigh to Saint Charlescar car 800.9 mi
    14h 33m
    $147–212

  6. Train to Piedmont Triad International Airport, fly

    1. Take the train from Raleigh Union Station to Greensborotrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Lambert–St. Louis International Airport (STL)plane plane GSO - STL
    7h 50m
    $175–791

Raleigh to Saint Charles by bus

Calendar12Weekly Buses
Duration23h 58mAverage Duration
Ticket$138Cheapest Price
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Questions & Answers

Map of how to get from Raleigh to Saint Charles.ExpandLaunch map view
  • Distance: 693.2 mi
  • Duration: 4h 49m

What companies run services between Raleigh, NC, USA and Saint Charles, MO, USA?

Southwest Airlines, American Airlines, and Delta fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from GoRaleigh Station to 4375 Rider Trail North Sb via Capital Blvd at Crabtree Blvd, Raleigh Bus Station, Atlanta Bus Station, St Louis Bus Station, Civic Center Transit Center, and North Hanley Transit Center in around 23h 58m.

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