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How to get fromRaleigh to Saint Charlesby plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or train

Find Transport to Saint Charles

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There are 8 ways to get from Raleigh to Saint Charles by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Raleigh-Durham International Airport

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL)plane plane RDU - STL
    5h 8m
    $572–1,126

  2. Drive to Albert J. Ellis Airport, fly

    cheapest
    1. Drive from Raleigh to Albert J. Ellis Airport (OAJ)car car
    2. Fly from Albert J. Ellis Airport (OAJ) to Lambert–St. Louis International Airport (STL)plane plane OAJ - STL
    7h 33m
    $139–601

  3. Bus

    1. Take the bus from Raleigh Bus Station to Atlanta Bus Stationbus bus Greyhound US0670 / ...
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    24h 17m
    $154–273

  4. Train (Amtrak)

    1. Take the train from Raleigh Union Station to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    31h 48m
    $762–1,172

  5. Drive  800.9 mi

    1. Drive from Raleigh to Saint Charlescar car 800.9 mi
    14h 36m
    $147–212

  6. Bus to Fayetteville Municipal Airport, fly

    1. Take the bus from Raleigh Bus Station to Fayetteville Bus Stationbus bus
    2. Fly from Fayetteville Municipal Airport (FAY) to Lambert–St. Louis International Airport (STL)plane plane FAY - STL
    7h 40m
    $141–610

  7. Train to Piedmont Triad International Airport, fly

    1. Take the train from Raleigh Union Station to Greensborotrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Lambert–St. Louis International Airport (STL)plane plane GSO - STL
    8h 14m
    $204–782

  8. Bus to Greenville, fly

    1. Take the bus from Raleigh Bus Station to Greenville GK Butterfield Trans Ctrbus bus
    2. Fly from Greenville (PGV) to Lambert–St. Louis International Airport (STL)plane plane PGV - STL
    8h 39m
    $140–604

Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL) flights

Calendar45Weekly Planes
Duration3h 23mAverage Duration
Ticket$102Cheapest Price
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Comparing Your Travel Options

Map of how to get from Raleigh to Saint Charles.ExpandLaunch map view
  • Distance: 698.8 mi
  • Duration: 5h 8m

What companies run services between Raleigh, NC, USA and Saint Charles, MO, USA?

Southwest Airlines, American Airlines, and Delta fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from GoRaleigh Station to Saint Charles via Capital Blvd at Crabtree Blvd, Raleigh Bus Station, Atlanta Bus Station, St Louis Bus Station, Civic Center Transit Center, North Hanley Transit Center, and 4375 Rider Trail North Sb in around 24h 17m.

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