There are 7 ways to get from Raleigh to Santee by bus, taxi, train, car, plane, bus (Greyhound, Flixbus), or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, taxi
best- Take the bus from Raleigh Bus Station to Sumter Bus Stopbus Greyhound US0645S
- Take the taxi from Sumter Bus Stop to Santeetaxi
5h 55m$141–211Drive 212.7 mi
cheapest- Drive from Raleigh to Santeecar 212.7 mi
3h 32m$39–57Train, drive (Amtrak)
- Take the train from Raleigh Union Station to Selma Stationtrain
- Take the train from Selma Station to Charleston Amtrak Stationtrain
- Drive from Charleston Amtrak Station to Santeecar
6h 52m$89–185Fly to Columbia, drive
- Fly from Raleigh-Durham International Airport (RDU) to Columbia (CAE)plane RDU - CAE
- Drive from Columbia-Airport-CAE to Santeecar
5h 49m$122–818Bus via Charlotte
- Take the bus from Raleigh Bus Station to Charlotte Bus Stationbus Greyhound US0700 / ...
- Take the bus from Charlotte to Orangeburgbus Ses 996 / ...
7h 39mBus
- Take the bus from S Saunders St at Chapanoke Rd - Raleigh to Camdenbus Nyc
- Take the bus from Camden to Orangeburgbus Greyhound US0644S
8h 32m$134–188Fly to Charleston International Airport, drive
- Fly from Raleigh-Durham International Airport (RDU) to Charleston International Airport (CHS)plane RDU - CHS
- Drive from Charleston-Airport-CHS to Santeecar
5h 57m$262–618
Raleigh-Durham International Airport (RDU) to Columbia (CAE) flights
Questions & Answers
The cheapest way to get from Raleigh to Santee is to drive which costs $35 - $60 and takes 3h 32m.
The fastest way to get from Raleigh to Santee is to drive which takes 3h 32m and costs $35 - $60.
No, there is no direct bus from Raleigh station to Santee. However, there are services departing from GoRaleigh Station and arriving at Orangeburg via Raleigh Bus Station and Charlotte. The journey, including transfers, takes approximately 7h 39m.
The distance between Raleigh and Santee is 229 miles. The road distance is 214 miles.
The best way to get from Raleigh to Santee without a car is to bus and taxi which takes 5h 55m and costs $140 - $220.
It takes approximately 5h 55m to get from Raleigh to Santee, including transfers.
Raleigh to Santee bus services, operated by Greyhound-us, depart from Raleigh Bus Station.
Raleigh to Santee bus services, operated by Greyhound-us, arrive at Charlotte Bus Station.
Yes, the driving distance between Raleigh to Santee is 214 miles. It takes approximately 3h 32m to drive from Raleigh to Santee.
There are 35+ hotels available in Santee.
What companies run services between Raleigh, NC, USA and Santee, SC, USA?
You can take a bus from GoRaleigh Station to Santee via Capital Blvd at Crabtree Blvd, Raleigh Bus Station, Charlotte, and Orangeburg in around 7h 39m.
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Columbia via Charlotte
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- $110–800
Flights from Raleigh-Durham International Airport to Columbia via Reagan Washington
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Raleigh-Durham International Airport to Columbia via Philadelphia
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $230–1,200
Flights from Raleigh-Durham International Airport to Columbia via New York La Guardia
- Ave. Duration
- 6h 38m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $270–1,300
Flights from Raleigh-Durham International Airport to Charleston International Airport via Charlotte
- Ave. Duration
- 3h 36m
- When
- Every day
- Estimated price
- $55–360
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Columbia via Atlanta
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $170–1,000
Flights from Raleigh-Durham International Airport to Columbia via New York La Guardia
- Ave. Duration
- 6h 12m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $270–1,300
Flights from Raleigh-Durham International Airport to Charleston International Airport via Atlanta
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $85–440
- Website
- united.com
Flights from Raleigh-Durham International Airport to Columbia via Washington Dulles
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Raleigh-Durham International Airport to Charleston International Airport via Washington Dulles
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $85–460
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Charleston International Airport via Baltimore
- Ave. Duration
- 3h 50m
- When
- Tuesday, Wednesday, Sunday, Monday, Thursday, and Friday
- Estimated price
- $90–470
- Website
- flybreeze.com
Flights from Raleigh-Durham International Airport to Charleston International Airport via Pittsburgh
- Ave. Duration
- 4h 39m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $220–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Raleigh Union Station to Selma Station
- Ave. Duration
- 33 min
- Frequency
- Once daily
- Estimated price
- $9–19
- Website
- https://www.amtrak.com/home.html
Train from Selma Station to Charleston Amtrak Station
- Ave. Duration
- 4h 18m
- Frequency
- Once daily
- Estimated price
- $70–150
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Raleigh Bus Station to Sumter Bus Stop
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
Bus from Raleigh Bus Station to Charlotte Bus Station
- Ave. Duration
- 2h 45m
- Frequency
- Every 4 hours
- Estimated price
- $22–45
- Website
- https://www.greyhound.com/
Bus from Camden to Orangeburg
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $13–27
- Website
- https://www.greyhound.com/
- Website
- example.com
Bus from Raleigh Bus Station to Sumter Bus Stop
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Schedules at
- example.com
Bus from Charlotte to Orangeburg
- Ave. Duration
- 2h 45m
- Frequency
- Twice daily
- Schedules at
- example.com
- Website
- greyhound.com
Bus from Raleigh Bus Station to Charlotte Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- Every 4 hours
- Schedules at
- greyhound.com
- Website
- flixbus.com
Bus from Raleigh Bus Station to Charlotte Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Once daily
- Schedules at
- flixbus.com
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Raleigh Bus Station to Charlotte Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- 5 times a week
- Estimated price
- $23–40
- Schedules at
- flixbus.com
- Phone
- +1 646-630-7186
- [email protected]
- Website
- wandacoach.com
Bus from S Saunders St at Chapanoke Rd - Raleigh to Camden
- Ave. Duration
- 3h 26m
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Adult One Way
- $40–60
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