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How to get fromRaleigh to St. Louisby plane, bus (Flixbus, Amtrak), train (Amtrak), car, train, or bus (Greyhound, Flixbus)

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There are 6 ways to get from Raleigh to St. Louis by plane, bus (Flixbus, Amtrak), train (Amtrak), car, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Raleigh-Durham International Airport

    best
    1. Fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL)plane plane RDU - STL
    4h 24m
    $126–656

  2. Bus via Carbondale

    1. Take the bus from Durham to Atlanta Downtownbus bus
    2. Take the bus from Atlanta Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the bus from Carbondale to St. Louisbus bus
    20h 50m
    $140–276

  3. Train (Amtrak)

    1. Take the train from Raleigh Union Station to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    30h 14m
    $444–886

  4. Drive 779.9 mi

    1. Drive from Raleigh to St. Louiscar car 779.9 mi
    14h 9m
    $143–206

  5. Train to Piedmont Triad International Airport, fly

    1. Take the train from Raleigh Union Station to Greensborotrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Lambert–St. Louis International Airport (STL)plane plane GSO - STL
    7h 28m
    $200–895

  6. Bus

    1. Take the bus from Raleigh Bus Station to Atlanta Bus Stationbus bus Greyhound US0670 / ...
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus Greyhound US0186
    21h 53m
    $141–291

Raleigh to St. Louis by bus and subway

Calendar5Weekly Services
Duration20h 50mAverage Duration
Ticket$140Cheapest Price
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Questions & Answers

Map of how to get from Raleigh to St. Louis.ExpandLaunch map view
  • Distance: 693.1 mi
  • Duration: 4h 24m

What companies run services between Raleigh, NC, USA and St. Louis, MO, USA?

Southwest Airlines, Delta, and American Airlines fly from Raleigh-Durham International Airport (RDU) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, you can take a bus from Union Station - Bus Platform A to St. Louis via Durham, Atlanta Downtown, Civic Center Station, Garnett Station, Atlanta Bus Station, and Carbondale in around 20h 50m.

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