There are 7 ways to get from Reading to Syracuse by bus (Greyhound, Flixbus), train (Amtrak), car, train, plane, bus (Flixbus), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Boston to Syracuse Bus Stationbus Greyhound US0171 / ...
8h 20m$50–97Train (Amtrak)
- Take the train from Boston to Syracuse Regional Transportation Centertrain Lake Shore Limited
10h 34m$104–240Drive 316.6 mi
- Drive from Reading to Syracusecar 316.6 mi
5h 37m$58–84Train, fly to Syracuse Hancock International Airport
- Take the train from Reading to North Stationtrain
- Fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR)plane BOS - SYR
5h 18m$86–569Bus via West Albany
- Take the bus from Boston to Albanybus FlixBus 2691
- Take the bus from Albany to Syracusebus Adt A264
9h 43m$52–92Fly to Rochester, train
- Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane BOS - ROC
- Take the train from Rochester to Syracuse Regional Transportation Centertrain
6h 16m$129–803Fly to Buffalo Niagara International Airport, bus
- Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane BOS - BUF
- Take the bus from Buffalo Niagara International Airport to Syracuse Bus Stationbus
7h 31m$112–651
Reading to Syracuse by bus, subway, and foot
Questions & Answers
The cheapest way to get from Reading to Syracuse is to bus which costs $45 - $100 and takes 8h 20m.
The fastest way to get from Reading to Syracuse is to train and fly which takes 5h 18m and costs $85 - $600.
No, there is no direct bus from Reading to Syracuse station. However, there are services departing from Walkers Brook Dr @ New Crossing Rd and arriving at Syracuse Bus Station via Boston. The journey, including transfers, takes approximately 8h 20m.
No, there is no direct train from Reading to Syracuse. However, there are services departing from Reading and arriving at Syracuse Regional Transportation Center via Oak Grove and Boston. The journey, including transfers, takes approximately 10h 34m.
The distance between Reading and Syracuse is 333 miles. The road distance is 318.4 miles.
The best way to get from Reading to Syracuse without a car is to bus which takes 8h 20m and costs $45 - $100.
It takes approximately 8h 20m to get from Reading to Syracuse, including transfers.
Reading to Syracuse bus services, operated by Greyhound USA, depart from Boston station.
Reading to Syracuse train services, operated by Amtrak, depart from Boston station.
The best way to get from Reading to Syracuse is to bus which takes 8h 20m and costs $45 - $100. Alternatively, you can train, which costs $100 - $240 and takes 10h 34m.
What companies run services between Reading, MA, USA and Syracuse, NY, USA?
Greyhound USA operates a bus from Boston to Syracuse Bus Station twice daily. Tickets cost $45–90 and the journey takes 6h 25m. Flixbus USA also services this route 3 times a week. Alternatively, Amtrak operates a train from Boston to Syracuse Regional Transportation Center once daily. Tickets cost $100–230 and the journey takes 8h 54m.
- Website
- aa.com
Flights from Boston Logan Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $80–550
Flights from Boston Logan Airport to Rochester
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $85–600
Flights from Boston Logan Airport to Rochester via Philadelphia
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $110–650
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $80–550
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 3h 58m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–600
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 4h 3m
- When
- Saturday
- Estimated price
- $90–550
- Website
- southwest.com
Flights from Boston Logan Airport to Rochester via Baltimore
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $120–700
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 3h 48m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $110–600
- Website
- jetblue.com
Flights from Boston Logan Airport to Syracuse Hancock International Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $80–550
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $80–550
- Website
- united.com
Flights from Boston Logan Airport to Rochester via Washington Dulles
- Ave. Duration
- 3h 53m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $130–700
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Newark
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $90–550
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 4h 3m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–650
- Website
- delta.com
Flights from Boston Logan Airport to Rochester via New York La Guardia
- Ave. Duration
- 3h 47m
- When
- Monday to Friday
- Estimated price
- $100–600
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 3h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $90–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Syracuse Regional Transportation Center
- Ave. Duration
- 8h 54m
- Frequency
- Once daily
- Estimated price
- $100–230
- Website
- Amtrak
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- 5 times a day
- Estimated price
- $24–55
- Website
- Amtrak
Train from Reading to North Station
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- $2–8
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $2–8
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Rochester to Syracuse Regional Transportation Center
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $21–170
- Website
- VIA Rail
- Escape
- $21–75
- Business
- $50–150
- Business Plus
- $65–170
- Economy
- $24–80
- Economy Plus
- $26–90
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Boston to Syracuse Bus Station
- Ave. Duration
- 6h 25m
- Frequency
- Twice daily
- Estimated price
- $45–90
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Boston to Syracuse Bus Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a week
- Estimated price
- $45–80
- Schedules at
- Flixbus USA
Bus from Boston to Albany
- Ave. Duration
- 3h 50m
- Frequency
- 3 times a week
- Estimated price
- $26–45
- Schedules at
- Flixbus USA
Bus from Albany to Syracuse
- Ave. Duration
- 2h 35m
- Frequency
- 3 times a week
- Estimated price
- $21–40
- Schedules at
- Flixbus USA
Bus from Buffalo Niagara International Airport to Syracuse Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- Every 4 hours
- Estimated price
- $22–40
- Schedules at
- Flixbus USA
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Albany to Syracuse
- Saver
- $26–85
- Flexible
- $50–90
Bus from Buffalo Niagara International Airport to Syracuse Bus Station
- Saver
- $27–85
- Flexible
- $50–90
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More Questions & Answers
Reading to Syracuse bus services, operated by Greyhound USA, arrive at Syracuse Bus Station.
Reading to Syracuse train services, operated by Amtrak, arrive at Syracuse Regional Transportation Center station.
Yes, the driving distance between Reading to Syracuse is 318 miles. It takes approximately 5h 37m to drive from Reading to Syracuse.
There are 94+ hotels available in Syracuse.

















