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How to get fromReading to Des Moinesby taxi, plane, bus, train, car, bus (Flixbus, Greyhound), or bus (Flixbus)

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There are 10 ways to get from Reading to Des Moines by taxi, plane, bus, train, car, bus (Flixbus, Greyhound), or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi to Lancaster, fly

    best
    1. Take the taxi from Reading to Lancaster-Airport-LNStaxi taxi
    2. Fly from Lancaster (LNS) to Des Moines (DSM)plane plane LNS - DSM
    5h 45m
    $226–802

  2. Bus

    cheapest
    1. Take the bus from Reading to Harrisburg Bus Stationbus bus
    2. Take the bus from Harrisburg Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    26h 35m
    $165–325

  3. Bus, train

    1. Take the bus from Reading to Pittsburgh Intermodal Stationbus bus
    2. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago to Des Moinesbus bus
    25h

  4. Bus, train via Galesburg

    1. Take the bus from Reading to Harrisburg Bus Stationbus bus
    2. Take the train from Harrisburg to Pittsburgh Amtrak Stationtrain train
    3. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    5. Take the bus from Galesburg to Des Moinesbus bus
    28h 16m
    $320–670

  5. Drive 1,020.2 mi

    1. Drive from Reading to Des Moinescar car 1,020.2 mi
    17h 15m
    $187–269

  6. Bus to Philadelphia International Airport, fly

    1. Take the bus from Reading to Philadelphiabus bus
    2. Fly from Philadelphia International Airport (PHL) to Des Moines (DSM)plane plane PHL - DSM
    6h 5m

  7. Bus to Harrisburg International Airport, fly

    1. Take the bus from Reading to Harrisburg Bus Stationbus bus
    2. Fly from Harrisburg International Airport (MDT) to Des Moines (DSM)plane plane MDT - DSM
    8h 12m
    $328–1,538

  8. Bus to Lehigh Valley International Airport, fly

    1. Take the bus from Reading to Allentownbus bus
    2. Fly from Lehigh Valley International Airport (ABE) to Des Moines (DSM)plane plane ABE - DSM
    7h 59m
    $174–783

  9. Bus via Chicago

    1. Take the bus from Reading to Chicago Bus Stationbus bus FlixBus N2642
    2. Take the bus from Chicago to Des Moinesbus bus Btw 1205 / ...
    26h 50m

  10. Bus, train #2

    1. Take the bus from Reading to Philadelphia Bus Stationbus bus
    2. Take the train from 30th Street Station to Chicago Union Stationtrain train
    3. Take the bus from Chicago to Des Moinesbus bus
    38h 3m

Lancaster (LNS) to Des Moines (DSM) flights

Calendar26Weekly Planes
Duration7h 22mAverage Duration
Ticket$149Cheapest Price
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Questions & Answers

Map of how to get from Reading to Des Moines.ExpandLaunch map view
  • Distance: 945.2 mi
  • Duration: 5h 45m

What companies run services between Reading, PA, USA and Des Moines, IA, USA?

You can take a bus from Reading to Des Moines via Harrisburg Bus Station and Indianapolis Union Station in around 26h 35m.

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