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How to get fromReading to Florenceby bus (Flixbus, Greyhound), bus, train, car, or plane

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There are 10 ways to get from Reading to Florence by bus (Flixbus, Greyhound), bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Raleigh

    best
    1. Take the bus from Reading to Philadelphia Bus Stationbus bus
    2. Take the bus from Philadelphia Bus Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Raleigh Bus Stationbus bus
    4. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    13h 51m
    $87–174

  2. Bus, train

    1. Take the bus from Reading to Philadelphia Bus Stationbus bus FlixBus 2650 / ...
    2. Take the train from 30th Street Station to Florence Stationtrain train Palmetto / ...
    15h 34m
    $182–377

  3. Drive 535.5 mi

    1. Drive from Reading to Florencecar car 535.5 mi
    9h 37m
    $98–142

  4. Bus to Harrisburg International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from Reading to Harrisburg Bus Stationbus bus
    2. Fly from Harrisburg International Airport (MDT) to Charlotte Douglas International Airport (CLT)plane plane MDT - CLT
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the bus from Camden to Florence Bus Stationbus bus
    10h 36m
    $202–1,160

  5. Bus

    1. Take the bus from Reading to Newarkbus bus
    2. Take the bus from Terminal B to Grand Centralbus bus
    3. Take the bus from New York, NY to Florence, SCbus bus Nyc
    17h 21m
    $149–200

  6. Bus to Philadelphia International Airport, fly to Myrtle Beach, bus, train

    1. Take the bus from Reading to Philadelphia Bus Stationbus bus
    2. Fly from Philadelphia International Airport (PHL) to Myrtle Beach (MYR)plane plane PHL - MYR
    3. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    4. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    10h 52m
    $140–548

  7. Bus to Lehigh Valley International Airport, fly to Charlotte Douglas International Airport, bus

    1. Take the bus from Reading to Allentownbus bus
    2. Fly from Lehigh Valley International Airport (ABE) to Charlotte Douglas International Airport (CLT)plane plane ABE - CLT
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the bus from Camden to Florence Bus Stationbus bus
    10h 56m
    $122–606

  8. Bus to Harrisburg International Airport, fly to Myrtle Beach, bus, train

    1. Take the bus from Reading to Harrisburg Bus Stationbus bus
    2. Fly from Harrisburg International Airport (MDT) to Myrtle Beach (MYR)plane plane MDT - MYR
    3. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    4. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    11h 8m
    $165–775

  9. Bus to Lehigh Valley International Airport, fly to Myrtle Beach, bus, train

    1. Take the bus from Reading to Allentownbus bus
    2. Fly from Lehigh Valley International Airport (ABE) to Myrtle Beach (MYR)plane plane ABE - MYR
    3. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    4. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    11h 25m
    $120–431

  10. Bus, train to Baltimore-Washington International Airport, fly to Myrtle Beach, train

    1. Take the bus from Reading to Philadelphia Bus Stationbus bus
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Myrtle Beach (MYR)plane plane BWI - MYR
    4. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus
    5. Take the train from Charleston Amtrak Station to Florence Stationtrain train
    11h 48m
    $331–1,425

Reading to Florence by bus

Calendar28Weekly Buses
Duration13h 51mAverage Duration
Ticket$87Cheapest Price
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Questions & Answers

Map of how to get from Reading to Florence.ExpandLaunch map view
  • Distance: 603.4 mi
  • Duration: 13h 51m

What companies run services between Reading, PA, USA and Florence, SC, USA?

You can take a bus from Reading to Florence Bus Station via Philadelphia Bus Station, Washington Union Station, and Raleigh Bus Station in around 13h 51m.

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