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How to get fromReading to St. Louisby bus, plane, bus (Flixbus, Greyhound), train, car, or bus (Flixbus)

Find Transport to St. Louis

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There are 9 ways to get from Reading to St. Louis by bus, plane, bus (Flixbus, Greyhound), train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Philadelphia International Airport, fly

    best
    1. Take the bus from Reading to Philadelphia Bus Stationbus bus
    2. Fly from Philadelphia International Airport (PHL) to Lambert–St. Louis International Airport (STL)plane plane PHL - STL
    6h 7m
    $135–773

  2. Bus

    1. Take the bus from Reading to Harrisburg Bus Stationbus bus FlixBus 2642 / ...
    2. Take the bus from Harrisburg Bus Station to St Louis Bus Stationbus bus Greyhound US0421
    20h 35m
    $139–223

  3. Bus, train

    1. Take the bus from Reading to Harrisburg Bus Stationbus bus
    2. Take the train from Harrisburg to Pittsburgh Amtrak Stationtrain train
    3. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to St. Louistrain train
    24h 31m
    $549–873

  4. Drive  836.9 mi

    1. Drive from Reading to St. Louiscar car 836.9 mi
    14h 15m
    $153–221

  5. Bus to Newark Liberty International Airport, fly

    1. Take the bus from Reading to Newarkbus bus
    2. Fly from Newark Liberty International Airport (EWR) to Lambert–St. Louis International Airport (STL)plane plane EWR - STL
    6h 50m
    $329–945

  6. Bus, train to Baltimore-Washington International Airport, fly

    1. Take the bus from Reading to Philadelphia Bus Stationbus bus
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Lambert–St. Louis International Airport (STL)plane plane BWI - STL
    7h 15m
    $147–1,319

  7. Bus, train to Ronald Reagan Washington National Airport, fly

    1. Take the bus from Reading to Philadelphia Bus Stationbus bus
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Lambert–St. Louis International Airport (STL)plane plane DCA - STL
    8h 13m
    $177–1,106

  8. Bus, train to Laguardia Airport, fly

    1. Take the bus from Reading to Philadelphia Bus Stationbus bus
    2. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Fly from Laguardia Airport (LGA) to Lambert–St. Louis International Airport (STL)plane plane LGA - STL
    8h 46m
    $181–1,076

  9. Bus via Chicago (Flixbus)

    1. Take the bus from Reading to Chicago Bus Stationbus bus FlixBus N2642
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    25h 35m
    $175–269

Reading to St. Louis by bus

Calendar10Weekly Buses
Duration20h 35mAverage Duration
Ticket$139Cheapest Price
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Comparing Your Travel Options

Map of how to get from Reading to St. Louis.ExpandLaunch map view
  • Distance: 889.4 mi
  • Duration: 6h 7m

What companies run services between Reading, PA, USA and St. Louis, MO, USA?

You can take a bus from Reading to St Louis Bus Station via Harrisburg Bus Station in around 20h 35m.

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