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How to get fromRegina to Mayo Clinicby plane, bus, car, or train

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There are 4 ways to get from Regina to Mayo Clinic by plane, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester

    best
    1. Fly from Regina (YQR) to Rochester (RST)plane plane YQR - RST
    12h 18m
    $92–516

  2. Bus, drive, train

    1. Take the bus from Regina to Lethbridgebus bus
    2. Drive from Lethbridge to Port of Sweet Grasscar car
    3. Take the bus from Port of Sweet Grass to Shelby Transit Centerbus bus
    4. Take the train from Shelby Amtrak Station to St. Paul-Minneapolistrain train
    5. Take the bus from St. Paul to Rochesterbus bus
    34h 48m
    $657–1,056

  3. Drive  822.8 mi

    1. Drive from Regina to Mayo Cliniccar car 822.8 mi
    14h 54m
    $189–272

  4. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Regina (YQR) to Minneapolis–Saint Paul International Airport (MSP)plane plane YQR - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    5h 35m
    $208–874

Regina (YQR) to Rochester (RST) flights

Calendar32Weekly Planes
Duration14h 37mAverage Duration
Ticket$91Cheapest Price
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Comparing Your Travel Options

Map of how to get from Regina to Mayo Clinic.ExpandLaunch map view
  • Distance: 735.6 mi
  • Duration: 12h 18m

What companies run services between Regina, SK, Canada and Mayo Clinic, MN, USA?

WestJet, Delta, and United Airlines fly from Regina (YQR) to Rochester (RST) 5 times a day.

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