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How to get fromReno to Knoxvilleby plane, bus (Greyhound, Flixbus), train, bus, or car

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There are 8 ways to get from Reno to Knoxville by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport

    best
    1. Fly from Reno/Tahoe International Airport (RNO) to Mcghee Tyson Airport (TYS)plane plane RNO - TYS
    6h 11m
    $358–1,259

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Reno/Tahoe International Airport (RNO) to Asheville Regional Airport (AVL)plane plane RNO - AVL
    2. Drive from Asheville-Airport-AVL to Knoxvillecar car
    8h 27m
    $194–704

  3. Bus

    1. Take the bus from Sparks Transit Center to Denver Union Stationbus bus
    2. Take the bus from Denver Union Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to New York Midtownbus bus
    4. Take the bus from New York to Knoxvillebus bus
    3d 3h
    $643–1,124

  4. Train, bus via Farragut

    1. Take the train from Reno to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus
    3d 7h
    $1,199–2,316

  5. Drive 2,300.7 mi

    1. Drive from Reno to Knoxvillecar car 2,300.7 mi
    36h 25m
    $420–607

  6. Fly to Nashville, drive

    1. Fly from Reno/Tahoe International Airport (RNO) to Nashville (BNA)plane plane RNO - BNA
    2. Drive from Nashville-Airport-BNA to Knoxvillecar car
    6h 49m
    $200–729

  7. Fly to Chattanooga Metropolitan Airport, drive

    1. Fly from Reno/Tahoe International Airport (RNO) to Chattanooga Metropolitan Airport (CHA)plane plane RNO - CHA
    2. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar car
    8h 3m
    $341–1,287

  8. Train, bus

    1. Take the train from Reno to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York, NY to Knoxville, TNbus bus
    3d 7h
    $1,154–2,226

Reno/Tahoe International Airport (RNO) to Mcghee Tyson Airport (TYS) flights

Calendar46Weekly Planes
Duration7h 15mAverage Duration
Ticket$302Cheapest Price
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Questions & Answers

Map of how to get from Reno to Knoxville.ExpandLaunch map view
  • Distance: 1,973.9 mi
  • Duration: 6h 11m

What companies run services between Reno, NV, USA and Knoxville, TN, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Reno/Tahoe International Airport (RNO) to Mcghee Tyson Airport (TYS) every 4 hours. Alternatively, you can take a bus from RTC 4th STREET STATION Bay I 4SS to Knoxville via Sparks Transit Center, Denver Union Station, Chicago Bus Station, New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 3d 3h.

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