Rome2Rio

How to get fromRoanoke to Chicago Union Stationby plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train

Find Transport to Chicago Union Station

See all options

There are 7 ways to get from Roanoke to Chicago Union Station by plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Roanoke Regional Airport-Woodrum Field

    best
    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Chicago O'Hare International Airport (ORD)plane plane ROA - ORD
    4h 36m
    $56–289

  2. Bus

    1. Take the bus from Roanoke Bus Stop to Nashville Bus Stationbus bus Greyhound US0600
    2. Take the bus from Nashville Bus Station to Chicago Bus Stationbus bus Greyhound US0100
    18h 50m
    $137–266

  3. Train (Amtrak)

    1. Take the train from Roanoke to Charlottesvilletrain train Northeast Regional
    2. Take the train from Charlottesville to Chicago Union Stationtrain train Cardinal
    24h 21m
    $297–624

  4. Drive 647.3 mi

    1. Drive from Roanoke to Chicago Union Stationcar car 647.3 mi
    11h 45m
    $119–171

  5. Drive to Greenbrier Valley Airport, fly

    1. Drive from Roanoke to Greenbrier Valley Airport (LWB)car car
    2. Fly from Greenbrier Valley Airport (LWB) to Chicago O'Hare International Airport (ORD)plane plane LWB - ORD
    4h 51m
    $65–303

  6. Train to Charlottesville, fly

    1. Take the train from Roanoke to Charlottesvilletrain train
    2. Fly from Charlottesville (CHO) to Chicago O'Hare International Airport (ORD)plane plane CHO - ORD
    6h 52m
    $119–409

  7. Train to Lynchburg Regional Airport, fly

    1. Take the train from Roanoke to Lynchburgtrain train
    2. Fly from Lynchburg Regional Airport (LYH) to Chicago O'Hare International Airport (ORD)plane plane LYH - ORD
    7h 15m
    $71–331

Roanoke to Chicago Union Station by bus and foot

Calendar14Weekly Services
Duration18h 50mAverage Duration
Ticket$137Cheapest Price
See schedules

Questions & Answers

Map of how to get from Roanoke to Chicago Union Station.ExpandLaunch map view
  • Distance: 556.1 mi
  • Duration: 4h 36m

What companies run services between Roanoke, VA, USA and Chicago Union Station, IL, USA?

American Airlines, United Airlines, and Delta fly from Roanoke Regional Airport-Woodrum Field (ROA) to Chicago O'Hare International Airport (ORD) every 2 hours. Alternatively, you can take a bus from Roanoke Bus Stop to Chicago Union Station via Nashville Bus Station and Chicago Bus Station in around 18h 50m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers