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How to get fromRoanoke to Florida Keysby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 6 ways to get from Roanoke to Florida Keys by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Roanoke Regional Airport-Woodrum Field

    best
    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Key West International Airport (EYW)plane plane ROA - EYW
    8h 42m
    $151–448

  2. Bus

    1. Take the bus from Roanoke Bus Stop to Lynchburg Transit Centerbus bus
    2. Take the bus from Lynchburg Transit Center to Richmondbus bus
    3. Take the bus from Richmond to Ft Lauderdale Broward Park & Ridebus bus
    4. Take the bus from Ft Lauderdale Broward Park & Ride to Miami Airport Stationbus bus
    5. Take the bus from Miami Airport Station to Big Pine Keybus bus
    32h 51m
    $190–345

  3. Bus, train

    1. Take the bus from Roanoke Bus Stop to Fredericksburg Bus Stopbus bus
    2. Take the train from Fredericksburg Amtrak to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    34h 51m
    $428–871

  4. Drive 1,030.4 mi

    1. Drive from Roanoke to Florida Keyscar car 1,030.4 mi
    18h 29m
    $189–272

  5. Drive to Greenbrier Valley Airport, fly

    1. Drive from Roanoke to Greenbrier Valley Airport (LWB)car car
    2. Fly from Greenbrier Valley Airport (LWB) to Key West International Airport (EYW)plane plane LWB - EYW
    11h 39m
    $160–462

  6. Train to Lynchburg Regional Airport, fly

    1. Take the train from Roanoke to Lynchburgtrain train
    2. Fly from Lynchburg Regional Airport (LYH) to Key West International Airport (EYW)plane plane LYH - EYW
    11h 52m
    $166–480

Roanoke to Florida Keys by bus and foot

Calendar4Weekly Services
Duration32h 51mAverage Duration
Ticket$190Cheapest Price
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Questions & Answers

Map of how to get from Roanoke to Florida Keys.ExpandLaunch map view
  • Distance: 916.6 mi
  • Duration: 8h 42m

What companies run services between Roanoke, VA, USA and Florida Keys, FL, USA?

Delta, American Airlines, and United Airlines fly from Roanoke Regional Airport-Woodrum Field (ROA) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Roanoke Bus Stop to Florida Keys via Lynchburg Transit Center, Richmond, Richmond, Ft Lauderdale Broward Park & Ride, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 32h 51m.

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