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How to get fromRoanoke to Florida Keysby plane, bus (Greyhound, Flixbus), bus, train, shuttle, or car

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There are 7 ways to get from Roanoke to Florida Keys by plane, bus (Greyhound, Flixbus), bus, train, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Roanoke Regional Airport-Woodrum Field

    best
    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Key West International Airport (EYW)plane plane ROA - EYW
    8h 37m
    $146–438

  2. Bus

    1. Take the bus from Roanoke Bus Stop to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    34h 30m
    $204–352

  3. Bus, train, shuttle

    1. Take the bus from Roanoke Bus Stop to Fredericksburg Bus Stopbus bus
    2. Take the train from Fredericksburg Amtrak to Miami Amtrak Stationtrain train
    3. Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Labshuttle bus
    34h 35m
    $492–912

  4. Drive  1,030.4 mi

    1. Drive from Roanoke to Florida Keyscar car 1,030.4 mi
    18h 29m
    $189–272

  5. Drive to Greenbrier Valley Airport, fly

    1. Drive from Roanoke to Greenbrier Valley Airport (LWB)car car
    2. Fly from Greenbrier Valley Airport (LWB) to Key West International Airport (EYW)plane plane LWB - EYW
    12h 3m
    $155–452

  6. Train to Lynchburg Regional Airport, fly

    1. Take the train from Roanoke to Lynchburgtrain train
    2. Fly from Lynchburg Regional Airport (LYH) to Key West International Airport (EYW)plane plane LYH - EYW
    11h 56m
    $158–467

  7. Train, bus

    1. Take the train from Roanoke to Alexandriatrain train
    2. Take the train from Alexandria to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    35h 19m
    $407–890

Roanoke to Florida Keys by bus and foot

Calendar4Weekly Services
Duration34h 30mAverage Duration
Ticket$204Cheapest Price
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Questions & Answers

Map of how to get from Roanoke to Florida Keys.ExpandLaunch map view
  • Distance: 916.6 mi
  • Duration: 8h 37m

What companies run services between Roanoke, VA, USA and Florida Keys, FL, USA?

Delta, American Airlines, and two other airlines fly from Roanoke Regional Airport-Woodrum Field (ROA) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Roanoke Bus Stop to Florida Keys via Washington Union Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 34h 30m.

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