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How to get fromRoanoke to Fort Myersby plane, bus (Greyhound, Flixbus), train, bus, or car

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There are 7 ways to get from Roanoke to Fort Myers by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Roanoke Regional Airport-Woodrum Field to Ft. Myers

    best
    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Ft. Myers (RSW)plane plane ROA - RSW
    8h 12m
    $97–499

  2. Bus via Charlotte

    1. Take the bus from Roanoke Bus Stop to Lynchburg Transit Centerbus bus
    2. Take the bus from Lynchburg Transit Center to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Orlando Bus Stationbus bus
    4. Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus bus
    25h
    $148–238

  3. Train, bus

    1. Take the train from Roanoke to Lynchburgtrain train
    2. Take the train from Lynchburg to Greensborotrain train
    3. Take the train from Greensboro to Carytrain train
    4. Take the train from Cary to Tampatrain train
    5. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    28h 23m
    $250–594

  4. Drive  834.5 mi

    1. Drive from Roanoke to Fort Myerscar car 834.5 mi
    15h 13m
    $153–220

  5. Fly Roanoke Regional Airport-Woodrum Field to Sarasota–Bradenton International Airport, bus

    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Sarasota–Bradenton International Airport (SRQ)plane plane ROA - SRQ
    2. Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stopbus bus
    8h 59m
    $136–724

  6. Train to Lynchburg Regional Airport, fly to Ft. Myers

    1. Take the train from Roanoke to Lynchburgtrain train
    2. Fly from Lynchburg Regional Airport (LYH) to Ft. Myers (RSW)plane plane LYH - RSW
    11h 6m
    $108–527

  7. Bus

    1. Take the bus from Roanoke Bus Stop to Lynchburg Transit Centerbus bus
    2. Take the bus from Lynchburg Transit Center to Richmondbus bus
    3. Take the bus from Richmond to Orlando Bus Stationbus bus
    4. Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus bus
    26h 35m
    $168–263

Roanoke to Fort Myers by bus

Calendar4Weekly Buses
Duration25hAverage Duration
Ticket$148Cheapest Price
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Map of how to get from Roanoke to Fort Myers.ExpandLaunch map view
  • Distance: 774.6 mi
  • Duration: 8h 12m

What companies run services between Roanoke, VA, USA and Fort Myers, FL, USA?

Delta, United Airlines, and American Airlines fly from Roanoke Regional Airport-Woodrum Field (ROA) to Ft. Myers (RSW) every 2 hours. Alternatively, you can take a bus from Roanoke Bus Stop to Fort Myers Bus Stop via Lynchburg Transit Center, Charlotte Bus Station, and Orlando Bus Station in around 25h.

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