There are 7 ways to get from Roanoke to Great Lakes by plane, train, bus (Greyhound, Flixbus), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Roanoke Regional Airport-Woodrum Field, train
best- Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Chicago O'Hare International Airport (ORD)plane ROA - ORD
- Take the train from Clybourn to Great Lakestrain
6h 16m$61–306Bus
- Take the bus from Roanoke Bus Stop to Nashville Bus Stationbus Greyhound US0600
- Take the bus from Nashville Bus Station to Chicago Bus Stationbus Greyhound US0100
22h 46m$144–275Train
- Take the train from Roanoke to Charlottesvilletrain
- Take the train from Charlottesville to Chicago Union Stationtrain
- Take the train from Chicago OTC to Great Lakestrain
26h 21m$294–634Drive 682.2 mi
- Drive from Roanoke to Great Lakescar 682.2 mi
12h 29m$125–180Drive to Greenbrier Valley Airport, fly, train
- Drive from Roanoke to Greenbrier Valley Airport (LWB)car
- Fly from Greenbrier Valley Airport (LWB) to Chicago O'Hare International Airport (ORD)plane LWB - ORD
- Take the train from Clybourn to Great Lakestrain
6h 32m$70–310Train to Charlottesville, fly, train
- Take the train from Roanoke to Charlottesvilletrain
- Fly from Charlottesville (CHO) to Chicago O'Hare International Airport (ORD)plane CHO - ORD
- Take the train from Clybourn to Great Lakestrain
8h 32m$123–426Train to Lynchburg Regional Airport, fly, train
- Take the train from Roanoke to Lynchburgtrain
- Fly from Lynchburg Regional Airport (LYH) to Chicago O'Hare International Airport (ORD)plane LYH - ORD
- Take the train from Clybourn to Great Lakestrain
8h 55m$76–348
Roanoke to Great Lakes by bus, foot, and train
Questions & Answers
The cheapest way to get from Roanoke to Great Lakes is to drive which costs $120 - $180 and takes 12h 29m.
The fastest way to get from Roanoke to Great Lakes is to fly and train which takes 6h 16m and costs $60 - $310.
No, there is no direct bus from Roanoke to Great Lakes station. However, there are services departing from Roanoke Bus Stop and arriving at Highland Park Metra Station via Nashville Bus Station, Union Station Transit Center, Michigan & Hubbard and Howard CTA Station. The journey, including transfers, takes approximately 22h 46m.
No, there is no direct train from Roanoke to Great Lakes. However, there are services departing from Roanoke and arriving at Great Lakes via Charlottesville and Chicago OTC. The journey, including transfers, takes approximately 26h 21m.
The distance between Roanoke and Great Lakes is 584 miles. The road distance is 686.2 miles.
The best way to get from Roanoke to Great Lakes without a car is to bus which takes 22h 46m and costs $140 - $280.
It takes approximately 6h 16m to get from Roanoke to Great Lakes, including transfers.
Roanoke to Great Lakes bus services, operated by Greyhound USA, depart from Roanoke Bus Stop station.
Roanoke to Great Lakes train services, operated by Amtrak, depart from Roanoke station.
The best way to get from Roanoke to Great Lakes is to bus which takes 22h 46m and costs $140 - $280. Alternatively, you can train, which costs $290 - $650 and takes 26h 21m.
What companies run services between Roanoke, VA, USA and Great Lakes, IL, USA?
You can take a bus from Roanoke Bus Stop to Great Lakes via Nashville Bus Station, Chicago Bus Station, Union Station Transit Center, Michigan & Hubbard, Rogers & Paulina, Howard CTA Station, Highland Park Metra Station, and Highland Park in around 22h 46m. Alternatively, you can take a train from Roanoke to Great Lakes via Charlottesville, Chicago Union Station, Clinton & Quincy, Washington & Canal, and Chicago OTC in around 26h 21m.
- Website
- united.com
Flights from Roanoke Regional Airport-Woodrum Field to Chicago O'Hare International Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- $50–290
Flights from Roanoke Regional Airport-Woodrum Field to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $65–330
Flights from Charlottesville to Chicago O'Hare International Airport
- Ave. Duration
- 2h 7m
- When
- Every day
- Estimated price
- $50–300
Flights from Charlottesville to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $60–310
Flights from Lynchburg Regional Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 16m
- When
- Every day
- Estimated price
- $50–300
Flights from Lynchburg Regional Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $60–320
- Website
- aa.com
Flights from Roanoke Regional Airport-Woodrum Field to Chicago O'Hare International Airport
- Ave. Duration
- 2h 23m
- When
- Every day
- Estimated price
- $50–290
Flights from Roanoke Regional Airport-Woodrum Field to Chicago O'Hare International Airport via Charlotte
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $60–330
Flights from Greenbrier Valley Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 11m
- When
- Every day
- Estimated price
- $50–280
Flights from Charlottesville to Chicago O'Hare International Airport via Charlotte
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $65–340
Flights from Lynchburg Regional Airport to Chicago O'Hare International Airport via Charlotte
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $65–330
- Website
- delta.com
Flights from Roanoke Regional Airport-Woodrum Field to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $75–360
Flights from Charlottesville to Chicago O'Hare International Airport via Atlanta
- Ave. Duration
- 5h 9m
- When
- Every day
- Estimated price
- $80–380
- Phone
- +1 312-696-3872
- Website
- Metra
Train from Clybourn to Great Lakes
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- $2–3
- Website
- Metra
- Adult
- $2–3
Train from Chicago OTC to Great Lakes
- Ave. Duration
- 1h 11m
- Frequency
- Hourly
- Estimated price
- $5–7
- Website
- Metra
- Adult
- $5–7
Train from Clybourn to Great Lakes
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- $2–3
- Website
- Metra
- Adult
- $2–3
Train from Clybourn to Great Lakes
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- $2–3
- Website
- Metra
- Adult
- $2–3
Train from Clybourn to Great Lakes
- Ave. Duration
- 1h 3m
- Frequency
- Hourly
- Estimated price
- $2–3
- Website
- Metra
- Adult
- $2–3
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Roanoke to Charlottesville
- Ave. Duration
- 2h 28m
- Frequency
- Twice daily
- Estimated price
- $35–75
- Website
- Amtrak
Train from Charlottesville to Chicago Union Station
- Ave. Duration
- 20h 53m
- Frequency
- 3 times a week
- Estimated price
- $250–550
- Website
- Amtrak
Train from Roanoke to Charlottesville
- Ave. Duration
- 2h 28m
- Frequency
- Twice daily
- Estimated price
- $35–75
- Website
- Amtrak
Train from Roanoke to Lynchburg
- Ave. Duration
- 1h 14m
- Frequency
- Twice daily
- Estimated price
- $16–35
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Roanoke Bus Stop to Nashville Bus Station
- Ave. Duration
- 8h 10m
- Frequency
- Twice daily
- Estimated price
- $65–130
- Website
- Greyhound
Bus from Nashville Bus Station to Chicago Bus Station
- Ave. Duration
- 10h
- Frequency
- Every 4 hours
- Estimated price
- $70–140
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Nashville Bus Station to Chicago Bus Station
- Ave. Duration
- 11h 25m
- Frequency
- 3 times a day
- Estimated price
- $75–130
- Schedules at
- Flixbus USA
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More Questions & Answers
Roanoke to Great Lakes bus services, operated by Greyhound USA, arrive at Nashville Bus Station.
Great Lakes is 1h behind Roanoke. It is currently 2:39 PM in Roanoke and 1:39 PM in Great Lakes.
Roanoke to Great Lakes train services, operated by Amtrak, arrive at Charlottesville station.
Yes, the driving distance between Roanoke to Great Lakes is 686 miles. It takes approximately 12h 29m to drive from Roanoke to Great Lakes.
There are 152+ hotels available in Great Lakes.








