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How to get fromRoanoke to Harrisburg–Carlisle metropolitan statistical areaby plane, train, bus, bus (Greyhound), car, or train (Amtrak)

Find Transport to Harrisburg–Carlisle metropolitan statistical area

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There are 7 ways to get from Roanoke to Harrisburg–Carlisle metropolitan statistical area by plane, train, bus, bus (Greyhound), car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Harrisburg International Airport

    best
    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Harrisburg International Airport (MDT)plane plane ROA - MDT
    5h 20m
    $50–306

  2. Train, bus

    1. Take the train from Roanoke to Washington Union Stationtrain train Northeast Regional
    2. Take the bus from Washington Union Station to Harrisburg Bus Stationbus bus Greyhound US0430
    9h 15m
    $84–178

  3. Bus (Greyhound)

    1. Take the bus from Roanoke Bus Stop to Baltimore Downtown Bus Stationbus bus Greyhound US0600
    2. Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus bus Greyhound US0430
    9h 55m
    $52–99

  4. Drive 287.7 mi

    1. Drive from Roanoke to Harrisburg–Carlisle metropolitan statistical areacar car 287.7 mi
    5h 5m
    $53–76

  5. Fly to Philadelphia International Airport, train

    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Philadelphia International Airport (PHL)plane plane ROA - PHL
    2. Take the train from 30th Street Station to Harrisburgtrain train
    6h 30m
    $97–482

  6. Train (Amtrak)

    1. Take the train from Roanoke to Washington Union Stationtrain train
    2. Take the train from Washington Union Station to 30th Street Stationtrain train
    3. Take the train from 30th Street Station to Harrisburgtrain train
    9h 55m
    $138–293

  7. Bus via Washington

    1. Take the bus from Salem VDOT Park & Ride to Washington Union Stationbus bus Highlands Rhythm
    2. Take the bus from Washington Union Station to Harrisburg Bus Stationbus bus Greyhound US0430
    10h 35m
    $53–89

Roanoke to Harrisburg–Carlisle metropolitan statistical area by train and bus

Calendar7Weekly Services
Duration9h 15mAverage Duration
Ticket$84Cheapest Price
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Questions & Answers

Map of how to get from Roanoke to Harrisburg–Carlisle metropolitan statistical area.ExpandLaunch map view
  • Distance: 280.8 mi
  • Duration: 5h 20m

What companies run services between Roanoke, VA, USA and Harrisburg–Carlisle metropolitan statistical area, PA, USA?

United Airlines, American Airlines, and Delta fly from Roanoke Regional Airport-Woodrum Field (ROA) to Harrisburg International Airport (MDT) every 2 hours. Alternatively, you can take a bus from Roanoke Bus Stop to Harrisburg Bus Station via Baltimore Downtown Bus Station in around 9h 55m.

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