Rome2Rio

How to get fromRoanoke to Indianapolisby plane, bus (Greyhound, Amtrak), train (Amtrak), car, or train

Find Transport to Indianapolis

See all options

There are 6 ways to get from Roanoke to Indianapolis by plane, bus (Greyhound, Amtrak), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Roanoke Regional Airport-Woodrum Field

    best
    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Indianapolis (IND)plane plane ROA - IND
    6h 26m
    $101–556

  2. Drive 470.1 mi

    cheapest
    1. Drive from Roanoke to Indianapoliscar car 470.1 mi
    8h 41m
    $86–124

  3. Bus

    1. Take the bus from Roanoke Bus Stop to Nashville Bus Stationbus bus Greyhound US0600
    2. Take the bus from Nashville Bus Station to Indianapolis Union Stationbus bus Greyhound US0100 / ...
    15h
    $114–183

  4. Train (Amtrak)

    1. Take the train from Roanoke to Charlottesvilletrain train Northeast Regional
    2. Take the train from Charlottesville to Indianapolistrain train Cardinal
    18h 51m
    $237–474

  5. Drive to Greenbrier Valley Airport, fly

    1. Drive from Roanoke to Greenbrier Valley Airport (LWB)car car
    2. Fly from Greenbrier Valley Airport (LWB) to Indianapolis (IND)plane plane LWB - IND
    8h 17m
    $110–570

  6. Train to Lynchburg Regional Airport, fly

    1. Take the train from Roanoke to Lynchburgtrain train
    2. Fly from Lynchburg Regional Airport (LYH) to Indianapolis (IND)plane plane LYH - IND
    8h 48m
    $116–588

Roanoke to Indianapolis by bus

Calendar7Weekly Buses
Duration15hAverage Duration
Ticket$114Cheapest Price
See schedules

Questions & Answers

Map of how to get from Roanoke to Indianapolis.ExpandLaunch map view
  • Distance: 401.6 mi
  • Duration: 6h 26m

What companies run services between Roanoke, VA, USA and Indianapolis, IN, USA?

United Airlines, American Airlines, and two other airlines fly from Roanoke Regional Airport-Woodrum Field (ROA) to Indianapolis (IND) hourly. Alternatively, you can take a bus from Roanoke Bus Stop to Indianapolis Union Station via Nashville Bus Station in around 15h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers