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How to get fromRoanoke to Key Westby plane, bus, train, shuttle, bus (Greyhound, Flixbus), or car

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There are 6 ways to get from Roanoke to Key West by plane, bus, train, shuttle, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Roanoke Regional Airport-Woodrum Field

    best
    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Key West International Airport (EYW)plane plane ROA - EYW
    5h 51m
    $80–357

  2. Bus, train, shuttle

    1. Take the bus from Roanoke Bus Stop to Fredericksburg Bus Stopbus bus
    2. Take the train from Fredericksburg Amtrak to Miami Amtrak Stationtrain train
    3. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus
    34h 59m
    $512–932

  3. Bus

    1. Take the bus from Roanoke Bus Stop to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    35h 16m
    $204–352

  4. Drive  1,045.8 mi

    1. Drive from Roanoke to Key Westcar car 1,045.8 mi
    18h 52m
    $191–276

  5. Drive to Greenbrier Valley Airport, fly

    1. Drive from Roanoke to Greenbrier Valley Airport (LWB)car car
    2. Fly from Greenbrier Valley Airport (LWB) to Key West International Airport (EYW)plane plane LWB - EYW
    9h 16m
    $89–371

  6. Train, bus

    1. Take the train from Roanoke to Alexandriatrain train
    2. Take the train from Alexandria to Miami Amtrak Stationtrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    36h 6m
    $407–890

Roanoke to Key West by bus, train, taxi, and shuttle

Calendar7Weekly Services
Duration34h 59mAverage Duration
Ticket$512Cheapest Price
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Questions & Answers

Map of how to get from Roanoke to Key West.ExpandLaunch map view
  • Distance: 897.4 mi
  • Duration: 5h 51m

What companies run services between Roanoke, VA, USA and Key West, FL, USA?

Delta, American Airlines, and two other airlines fly from Roanoke Regional Airport-Woodrum Field (ROA) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Roanoke Bus Stop to N Roosevelt & 3rd Street via Washington Union Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 35h 16m.

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