Rome2Rio

How to get fromRoanoke to Kirksvilleby plane, shuttle, bus, train, train (Amtrak), or car

Find Transport to Kirksville

See all options

There are 9 ways to get from Roanoke to Kirksville by plane, shuttle, bus, train, train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Roanoke Regional Airport-Woodrum Field to Columbia Regional Airport, shuttle

    best
    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Columbia Regional Airport (COU)plane plane ROA - COU
    2. Take a shuttle bus from Columbia to Hy-Vee - Kirksvilleshuttle bus
    9h 4m
    $138–485

  2. Fly Roanoke Regional Airport-Woodrum Field to Burlington Municipal Airport, drive

    cheapest
    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Burlington Municipal Airport (BRL)plane plane ROA - BRL
    2. Drive from Burlington Municipal Airport (BRL) to Kirksvillecar car
    11h 28m
    $70–279

  3. Bus, train

    1. Take the bus from Roanoke Bus Stop to Nashville Bus Stationbus bus
    2. Take the bus from Nashville Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Galesburgbus bus
    4. Take the train from Galesburg Amtrak Station to La Plata Stationtrain train
    24h 30m
    $231–400

  4. Train (Amtrak)

    1. Take the train from Roanoke to Charlottesvilletrain train
    2. Take the train from Charlottesville to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to La Plata Stationtrain train
    30h 30m
    $436–879

  5. Drive 858.2 mi

    1. Drive from Roanoke to Kirksvillecar car 858.2 mi
    15h 45m
    $157–227

  6. Fly Roanoke Regional Airport-Woodrum Field to Kirksville Regional Airport

    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Kirksville Regional Airport (IRK)plane plane ROA - IRK
    8h 13m
    $119–459

  7. Drive to Greenbrier Valley Airport, fly to Kirksville Regional Airport

    1. Drive from Roanoke to Greenbrier Valley Airport (LWB)car car
    2. Fly from Greenbrier Valley Airport (LWB) to Kirksville Regional Airport (IRK)plane plane LWB - IRK
    22h 3m
    $123–463

  8. Train to Lynchburg Regional Airport, fly to Kirksville Regional Airport

    1. Take the train from Roanoke to Lynchburgtrain train
    2. Fly from Lynchburg Regional Airport (LYH) to Kirksville Regional Airport (IRK)plane plane LYH - IRK
    10h 58m
    $134–491

  9. Fly Roanoke Regional Airport-Woodrum Field to Chicago O'Hare International Airport, train

    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Chicago O'Hare International Airport (ORD)plane plane ROA - ORD
    2. Take the train from Chicago Union Station to La Plata Stationtrain train
    10h 46m
    $196–554

Roanoke Regional Airport-Woodrum Field (ROA) to Columbia Regional Airport (COU) flights

Calendar35Weekly Planes
Duration6h 20mAverage Duration
Ticket$83Cheapest Price
See schedules

Questions & Answers

Map of how to get from Roanoke to Kirksville.ExpandLaunch map view
  • Distance: 786.6 mi
  • Duration: 9h 4m

What companies run services between Roanoke, VA, USA and Kirksville, MO, USA?

You can take a train from Roanoke to Kirksville via Charlottesville, Chicago Union Station, and La Plata Station in around 30h 30m. Alternatively, United Airlines, Corporate Flight Management Inc, and two other airlines fly from Roanoke Regional Airport-Woodrum Field (ROA) to Kirksville Regional Airport (IRK) every 4 hours.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers