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How to get fromRoanoke to Lancasterby train (Amtrak), bus (Greyhound), car, plane, train, or bus

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There are 7 ways to get from Roanoke to Lancaster by train (Amtrak), bus (Greyhound), car, plane, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Washington (Amtrak)

    best
    1. Take the train from Roanoke to Washington Union Stationtrain train
    2. Take the train from Washington Union Station to 30th Street Stationtrain train
    3. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train
    11h 33m
    $139–298

  2. Drive 304 mi

    cheapest
    1. Drive from Roanoke to Lancastercar car 304 mi
    5h 56m
    $56–81

  3. Bus (Greyhound)

    1. Take the bus from Roanoke Bus Stop to Baltimore Downtown Bus Stationbus bus Greyhound US0600
    2. Take the bus from Baltimore Downtown Bus Station to Harrisburg Bus Stationbus bus Greyhound US0430
    13h 7m
    $58–114

  4. Fly to Harrisburg International Airport, train, line 18 bus

    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Harrisburg International Airport (MDT)plane plane ROA - MDT
    2. Take the train from Harrisburg to Elizabethtown Amtrak Stationtrain train
    3. Take the bus from AMTRAK ETown to W. Chestnut & Water St.bus bus
    8h 38m

  5. Train (Amtrak)

    1. Take the train from Roanoke to 30th Street Stationtrain train Northeast Regional
    2. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train Keystone Service / ...
    12h 10m
    $143–296

  6. Bus via Washington

    1. Take the bus from Salem VDOT Park & Ride to Washington Union Stationbus bus Highlands Rhythm
    2. Take the bus from Washington Union Station to Harrisburg Bus Stationbus bus Greyhound US0430
    13h 47m
    $59–101

  7. Fly to Philadelphia International Airport, train

    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Philadelphia International Airport (PHL)plane plane ROA - PHL
    2. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train
    8h 8m
    $99–487

Roanoke to Lancaster by train and bus (Amtrak)

Calendar14Weekly Services
Duration11h 33mAverage Duration
Ticket$139Cheapest Price
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Questions & Answers

Map of how to get from Roanoke to Lancaster.ExpandLaunch map view
  • Distance: 464.2 mi
  • Duration: 11h 33m

What companies run services between Roanoke, VA, USA and Lancaster, PA, USA?

You can take a train from Roanoke to W. Chestnut & Water St. via Washington Union Station, 30th Street Station, Elizabethtown Amtrak Station, and AMTRAK ETown in around 11h 33m. Alternatively, you can take a bus from Roanoke Bus Stop to W. Chestnut & Water St. via Baltimore Downtown Bus Station, Harrisburg Bus Station, Harrisburg, Elizabethtown Amtrak Station, and AMTRAK ETown in around 13h 7m.

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