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How to get fromRoanoke to Milwaukeeby plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or bus (Flixbus)

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There are 7 ways to get from Roanoke to Milwaukee by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Roanoke Regional Airport-Woodrum Field to General Mitchell International Airport

    best
    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to General Mitchell International Airport (MKE)plane plane ROA - MKE
    6h 25m
    $107–557

  2. Fly Roanoke Regional Airport-Woodrum Field to Chicago O'Hare International Airport, bus

    cheapest
    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Chicago O'Hare International Airport (ORD)plane plane ROA - ORD
    2. Take the bus from Chicago to Milwaukee Intermodal Stationbus bus
    6h 8m
    $68–312

  3. Bus via Nashville

    1. Take the bus from Roanoke Bus Stop to Nashville Bus Stationbus bus
    2. Take the bus from Nashville Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    21h 45m
    $151–291

  4. Train (Amtrak)

    1. Take the train from Roanoke to Charlottesvilletrain train
    2. Take the train from Charlottesville to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    26h 50m
    $325–678

  5. Drive 734.7 mi

    1. Drive from Roanoke to Milwaukeecar car 734.7 mi
    13h 26m
    $135–194

  6. Drive to Greenbrier Valley Airport, fly to Chicago O'Hare International Airport, bus

    1. Drive from Roanoke to Greenbrier Valley Airport (LWB)car car
    2. Fly from Greenbrier Valley Airport (LWB) to Chicago O'Hare International Airport (ORD)plane plane LWB - ORD
    3. Take the bus from Chicago to Milwaukee Intermodal Stationbus bus
    6h 23m
    $72–326

  7. Bus

    1. Take the bus from 3rd St Station Slip D to Exit 118 - Park and Ridebus bus Swb
    2. Take the bus from Christiansburg to Wytheville Rural King Parking Lotbus bus
    3. Take the bus from Wytheville to Columbus - Mound Stbus bus
    4. Take the bus from Columbus to Milwaukee Intermodal Stationbus bus
    23h 13m
    $142–249

Roanoke to Milwaukee by bus

Calendar7Weekly Buses
Duration21h 45mAverage Duration
Ticket$151Cheapest Price
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Questions & Answers

Map of how to get from Roanoke to Milwaukee.ExpandLaunch map view
  • Distance: 585 mi
  • Duration: 6h 25m

What companies run services between Roanoke, VA, USA and Milwaukee, WI, USA?

United Airlines, Delta, and American Airlines fly from Roanoke Regional Airport-Woodrum Field (ROA) to General Mitchell International Airport (MKE) every 2 hours. Alternatively, you can take a bus from Roanoke Bus Stop to Milwaukee Intermodal Station via Nashville Bus Station and Chicago Bus Station in around 21h 45m.

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