There are 8 ways to get from Roanoke to Mississippi by plane, bus (Greyhound, Flixbus), train (Amtrak), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Gulfport-Biloxi Regional Airport
best- Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Gulfport-Biloxi Regional Airport (GPT)plane ROA - GPT
5h 49m$105–508Bus
- Take the bus from Roanoke Bus Stop to Nashville Bus Stationbus
- Take the bus from Nashville Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Jacksonbus
17h 25m$128–217Train (Amtrak)
- Take the train from Roanoke to Lynchburgtrain
- Take the train from Lynchburg to New Orleans Union Passenger Terminaltrain
- Take the train from New Orleans Union Passenger Terminal to Jacksontrain
30h 49m$309–740Drive 747.8 mi
- Drive from Roanoke to Jacksoncar 747.8 mi
12h 19m$137–198Fly to Memphis
- Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Memphis (MEM)plane ROA - MEM
5h 26m$156–781Fly to Jackson/Vicksburg
- Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Jackson/Vicksburg (JAN)plane ROA - JAN
5h 32m$119–454Fly to Mobile Regional Airport, bus
- Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Mobile Regional Airport (MOB)plane ROA - MOB
- Take the bus from Mobile Bus Station to Biloxi Transit Centerbus
8h 6m$107–438Train, bus
- Take the train from Roanoke to Lynchburgtrain
- Take the bus from Lynchburg Transit Center to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Atlanta Downtownbus
- Take the bus from Atlanta Bus Station to Jacksonbus
21h 33m$147–238
Roanoke to Mississippi by bus
Questions & Answers
The cheapest way to get from Roanoke to Mississippi is to bus which costs $120 - $220 and takes 17h 25m.
The fastest way to get from Roanoke to Mississippi is to fly which takes 5h 26m and costs $150 - $800.
No, there is no direct bus from Roanoke to Mississippi. However, there are services departing from Roanoke Bus Stop and arriving at Jackson via Nashville Bus Station and Memphis Bus Station. The journey, including transfers, takes approximately 17h 25m.
No, there is no direct train from Roanoke to Mississippi. However, there are services departing from Roanoke and arriving at Jackson via Lynchburg and New Orleans Union Passenger Terminal. The journey, including transfers, takes approximately 30h 49m.
The distance between Roanoke and Mississippi is 721 miles. The road distance is 752.1 miles.
The best way to get from Roanoke to Mississippi without a car is to bus which takes 17h 25m and costs $120 - $220.
It takes approximately 5h 49m to get from Roanoke to Mississippi, including transfers.
Roanoke to Mississippi bus services, operated by Greyhound USA, depart from Roanoke Bus Stop station.
Roanoke to Mississippi train services, operated by Amtrak, depart from Roanoke station.
The best way to get from Roanoke to Mississippi is to fly which takes 5h 49m and costs $100 - $550. Alternatively, you can bus, which costs $120 - $220 and takes 17h 25m, you could also train, which costs $300 - $750 and takes 30h 49m.
What companies run services between Roanoke, VA, USA and Mississippi, USA?
American Airlines and Delta fly from Roanoke Regional Airport-Woodrum Field (ROA) to Gulfport-Biloxi Regional Airport (GPT) 5 times a day. Alternatively, you can take a bus from Roanoke Bus Stop to Jackson via Nashville Bus Station and Memphis Bus Station in around 17h 25m.
- Website
- aa.com
Flights from Roanoke Regional Airport-Woodrum Field to Gulfport-Biloxi Regional Airport via Charlotte
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- $90–490
Flights from Roanoke Regional Airport-Woodrum Field to Memphis via Charlotte
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $130–750
Flights from Roanoke Regional Airport-Woodrum Field to Memphis via New York La Guardia
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $210–1,000
Flights from Roanoke Regional Airport-Woodrum Field to Memphis via Philadelphia
- Ave. Duration
- 7h 17m
- When
- Every day
- Estimated price
- $190–900
Flights from Roanoke Regional Airport-Woodrum Field to Memphis via Chicago O'Hare
- Ave. Duration
- 8h 2m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $170–850
Flights from Roanoke Regional Airport-Woodrum Field to Jackson/Vicksburg via Charlotte
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $75–400
Flights from Roanoke Regional Airport-Woodrum Field to Jackson/Vicksburg via Dallas/Ft.Worth
- Ave. Duration
- 6h 3m
- When
- Every day
- Estimated price
- $120–550
Flights from Roanoke Regional Airport-Woodrum Field to Mobile Regional Airport via Charlotte
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $70–400
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Roanoke to Lynchburg
- Ave. Duration
- 1h 14m
- Frequency
- Twice daily
- Estimated price
- $13–30
- Website
- Amtrak
Train from Lynchburg to New Orleans Union Passenger Terminal
- Ave. Duration
- 23h 56m
- Frequency
- Once daily
- Estimated price
- $250–600
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Jackson
- Ave. Duration
- 3h 39m
- Frequency
- Once daily
- Estimated price
- $45–110
- Website
- Amtrak
Train from Roanoke to Lynchburg
- Ave. Duration
- 1h 14m
- Frequency
- Twice daily
- Estimated price
- $13–30
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Roanoke Bus Stop to Nashville Bus Station
- Ave. Duration
- 8h 10m
- Frequency
- Once daily
- Estimated price
- $65–110
- Website
- Greyhound
Bus from Nashville Bus Station to Memphis Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- 4 times a day
- Estimated price
- $30–55
- Website
- Greyhound
Bus from Memphis Bus Station to Jackson
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $30–55
- Website
- Greyhound
Bus from Mobile Bus Station to Biloxi Transit Center
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $8–14
- Website
- Greyhound
Bus from Atlanta Bus Station to Jackson
- Ave. Duration
- 7h 40m
- Frequency
- Twice daily
- Estimated price
- $60–95
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Roanoke to Mississippi bus services, operated by Greyhound USA, arrive at Nashville Bus Station.
Mississippi is 1h behind Roanoke. It is currently 10:29 PM in Roanoke and 9:29 PM in Mississippi.
Roanoke to Mississippi train services, operated by Amtrak, arrive at Lynchburg station.
Yes, the driving distance between Roanoke to Mississippi is 752 miles. It takes approximately 12h 19m to drive from Roanoke to Mississippi.
Book your Roanoke to Mississippi train tickets online with Omio.
Book your Roanoke to Mississippi bus tickets online with Omio and FlixBus.
There are 227+ hotels available in Mississippi.





