There are 7 ways to get from Roanoke to Murrells Inlet by plane, train, bus, car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Roanoke Regional Airport-Woodrum Field
best- Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Myrtle Beach (MYR)plane ROA - MYR
5h 35m$84–344Drive 296.8 mi
cheapest- Drive from Roanoke to Murrells Inletcar 296.8 mi
6h 26m$55–79Train, bus
- Take the train from Roanoke to Lynchburgtrain
- Take the train from Lynchburg to High Pointtrain
- Take the bus from High Point to Fayettevillebus
- Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus
12h 48m$124–227Train, drive (Amtrak)
- Take the train from Roanoke to Lynchburgtrain
- Take the train from Lynchburg to Greensborotrain
- Take the train from Greensboro to Selma Stationtrain
- Take the train from Selma Station to Kingstree Stationtrain
- Drive from Kingstree Station to Murrells Inletcar
13h 35m$117–277Train to Lynchburg Regional Airport, fly
- Take the train from Roanoke to Lynchburgtrain
- Fly from Lynchburg Regional Airport (LYH) to Myrtle Beach (MYR)plane LYH - MYR
9h 31m$100–382Train, bus via Camden
- Take the train from Roanoke to Lynchburgtrain
- Take the train from Lynchburg to Charlotte Amtrak Stationtrain
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Myrtle Beach Bus Stationbus
14h 16m$132–260Bus
- Take the bus from Roanoke Bus Stop to Lynchburg Transit Centerbus
- Take the bus from Lynchburg Transit Center to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Myrtle Beach Bus Stationbus
14h 51m$113–172
Roanoke Regional Airport-Woodrum Field (ROA) to Myrtle Beach (MYR) flights
Comparing Your Travel Options
The cheapest way to get from Roanoke to Murrells Inlet is to drive which costs $50 - $80 and takes 6h 26m.
The fastest way to get from Roanoke to Murrells Inlet is to fly which takes 5h 35m and costs $80 - $350.
No, there is no direct bus from Roanoke to Murrells Inlet station. However, there are services departing from Roanoke Bus Stop and arriving at Myrtle Beach Bus Station via Lynchburg Transit Center, Charlotte Bus Station and Camden. The journey, including transfers, takes approximately 14h 51m.
The distance between Roanoke and Murrells Inlet is 280 miles. The road distance is 298.6 miles.
The best way to get from Roanoke to Murrells Inlet without a car is to train and bus which takes 12h 48m and costs $120 - $230.
It takes approximately 5h 35m to get from Roanoke to Murrells Inlet, including transfers.
Roanoke to Murrells Inlet bus services, operated by Greyhound USA, depart from Roanoke Bus Stop station.
The best way to get from Roanoke to Murrells Inlet is to fly which takes 5h 35m and costs $80 - $350. Alternatively, you can bus, which costs $110 - $180 and takes 14h 51m.
Roanoke to Murrells Inlet bus services, operated by Greyhound USA, arrive at Lynchburg Transit Center station.
Yes, the driving distance between Roanoke to Murrells Inlet is 299 miles. It takes approximately 6h 26m to drive from Roanoke to Murrells Inlet.
What companies run services between Roanoke, VA, USA and Murrells Inlet, SC, USA?
Delta, American Airlines, and United Airlines fly from Roanoke Regional Airport-Woodrum Field (ROA) to Myrtle Beach (MYR) every 2 hours. Alternatively, you can take a bus from Roanoke Bus Stop to Murrells Inlet via Lynchburg Transit Center, Charlotte Bus Station, Camden, and Myrtle Beach Bus Station in around 14h 51m.
- Website
- aa.com
Flights from Roanoke Regional Airport-Woodrum Field to Myrtle Beach via Philadelphia
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $70–380
Flights from Roanoke Regional Airport-Woodrum Field to Myrtle Beach via Charlotte
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $40–290
Flights from Lynchburg Regional Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $45–300
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Roanoke to Lynchburg
- Ave. Duration
- 1h 14m
- Frequency
- Twice daily
- Estimated price
- $12–30
- Website
- Amtrak
Train from Lynchburg to High Point
- Ave. Duration
- 2h 33m
- Frequency
- Once daily
- Estimated price
- $30–75
- Website
- Amtrak
Train from Roanoke to Lynchburg
- Ave. Duration
- 1h 14m
- Frequency
- Twice daily
- Estimated price
- $12–30
- Website
- Amtrak
Train from Lynchburg to Greensboro
- Ave. Duration
- 2h 9m
- Frequency
- Once daily
- Estimated price
- $27–65
- Website
- Amtrak
Train from Greensboro to Selma Station
- Ave. Duration
- 2h 22m
- Frequency
- Once daily
- Estimated price
- $26–65
- Website
- Amtrak
Train from Selma Station to Kingstree Station
- Ave. Duration
- 3h 18m
- Frequency
- Once daily
- Estimated price
- $40–100
- Website
- Amtrak
Train from Roanoke to Lynchburg
- Ave. Duration
- 1h 14m
- Frequency
- Twice daily
- Estimated price
- $12–30
- Website
- Amtrak
Train from Roanoke to Lynchburg
- Ave. Duration
- 1h 14m
- Frequency
- Twice daily
- Estimated price
- $12–30
- Website
- Amtrak
Train from Lynchburg to Charlotte Amtrak Station
- Ave. Duration
- 4h 14m
- Frequency
- Once daily
- Estimated price
- $45–120
- Website
- Amtrak
- Phone
- +1 704-348-1200
- [email protected]
- Website
- Sunway Charters
Bus from High Point to Fayetteville
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $17–25
- Schedules at
- Sunway Charters
- Passenger
- $17–25
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Booking & Getting There
There are 3229+ hotels available in Murrells Inlet.



