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How to get fromRoanoke to Port Saint Lucieby plane, taxi, bus (Greyhound, Flixbus), train, bus, or car

Find Transport to Port Saint Lucie

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There are 9 ways to get from Roanoke to Port Saint Lucie by plane, taxi, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Vero Beach Municipal Airport, taxi

    best
    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Vero Beach Municipal Airport (VRB)plane plane ROA - VRB
    2. Take the taxi from Vero Beach Municipal Airport (VRB) to Port Saint Lucietaxi taxi
    7h 9m
    $184–604

  2. Fly to Orlando Sanford, drive

    cheapest
    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Orlando Sanford (SFB)plane plane ROA - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Port Saint Luciecar car
    5h 49m
    $93–409

  3. Bus

    1. Take the bus from Roanoke Bus Stop to Lynchburg Transit Centerbus bus
    2. Take the bus from Lynchburg Transit Center to Richmondbus bus
    3. Take the bus from Richmond to Orlando Bus Stationbus bus
    4. Take the bus from Orlando Bus Station to Port St Luciebus bus
    25h 14m
    $171–300

  4. Train, bus

    1. Take the train from Roanoke to Lynchburgtrain train
    2. Take the train from Lynchburg to Greensborotrain train
    3. Take the train from Greensboro to Carytrain train
    4. Take the train from Cary to Kissimmee Amtrak Stationtrain train
    5. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    25h 47m
    $307–631

  5. Drive 776.4 mi

    1. Drive from Roanoke to Port Saint Luciecar car 776.4 mi
    13h 39m
    $142–205

  6. Fly to Melbourne International Airport, taxi, bus

    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Melbourne International Airport (MLB)plane plane ROA - MLB
    2. Take the taxi from Melbourne International Airport (MLB) to Sebastiantaxi taxi
    3. Take the bus from Sebastian to Port St Luciebus bus
    9h 42m
    $165–507

  7. Fly to President Donald J. Trump International Airport, bus

    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to President Donald J. Trump International Airport (PBI)plane plane ROA - PBI
    2. Take the bus from WPB ITC at BAY D to GATLIN BLVD at I-95 P/R LOTbus bus
    10h 14m
    $98–461

  8. Bus via Camden

    1. Take the bus from Roanoke Bus Stop to Lynchburg Transit Centerbus bus
    2. Take the bus from Lynchburg Transit Center to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the bus from Camden to Jacksonvillebus bus
    5. Take the bus from Jacksonville to Port St Luciebus bus
    27h 24m
    $139–278

  9. Train, bus via Arlington

    1. Take the train from Roanoke to Alexandriatrain train
    2. Take the train from Alexandria to West Palm Beach Amtrak Stationtrain train
    3. Take the bus from WPB ITC at BAY D to GATLIN BLVD at I-95 P/R LOTbus bus 95
    30h 26m
    $427–907

Roanoke to Port Saint Lucie by bus and foot

Calendar4Weekly Services
Duration25h 14mAverage Duration
Ticket$171Cheapest Price
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Questions & Answers

Map of how to get from Roanoke to Port Saint Lucie.ExpandLaunch map view
  • Distance: 702.6 mi
  • Duration: 7h 9m

What companies run services between Roanoke, VA, USA and Port Saint Lucie, FL, USA?

You can take a bus from Roanoke Bus Stop to SW PSL Blvd & SE Bayshore Blvd via Lynchburg Transit Center, Richmond, Richmond, Orlando Bus Station, and SW Gatlin Blvd & SW Brescia St in around 25h 14m.

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