There are 6 ways to get from Roanoke to Sanford by plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Orlando Sanford
best- Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Orlando Sanford (SFB)plane ROA - SFB
3h 19m$69–374Bus
- Take the bus from Roanoke Bus Stop to Lynchburg Transit Centerbus
- Take the bus from Lynchburg Transit Center to Richmondbus
- Take the bus from Richmond to Deltonabus
20h 31m$151–246Train (Amtrak)
- Take the train from Roanoke to Lynchburgtrain
- Take the train from Lynchburg to Greensborotrain
- Take the train from Greensboro to Carytrain
- Take the train from Cary to Delandtrain
21h 43m$250–553Drive 665.4 mi
- Drive from Roanoke to Sanfordcar 665.4 mi
11h 51m$122–176Fly to Orlando, train
- Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Orlando (MCO)plane ROA - MCO
- Take the train from Sand Lake Road to Sanfordtrain
7h 38m$74–391Bus, train
- Take the bus from Roanoke Bus Stop to Fredericksburg Bus Stopbus Greyhound US0600
- Take the train from Fredericksburg Amtrak to Delandtrain Silver Meteor
22h 50m$269–606
Roanoke to Sanford by train (Amtrak)
Questions & Answers
The cheapest way to get from Roanoke to Sanford is to drive which costs $120 - $180 and takes 11h 51m.
The fastest way to get from Roanoke to Sanford is to fly which takes 3h 19m and costs $65 - $380.
No, there is no direct bus from Roanoke to Sanford. However, there are services departing from Roanoke Bus Stop and arriving at Deltona via Lynchburg Transit Center and Richmond. The journey, including transfers, takes approximately 20h 31m.
No, there is no direct train from Roanoke to Sanford. However, there are services departing from Roanoke and arriving at Sanford via Lynchburg, Greensboro, Cary and DeLand. The journey, including transfers, takes approximately 21h 43m.
The distance between Roanoke and Sanford is 606 miles. The road distance is 669.3 miles.
The best way to get from Roanoke to Sanford without a car is to bus which takes 20h 31m and costs $150 - $250.
It takes approximately 3h 19m to get from Roanoke to Sanford, including transfers.
Roanoke to Sanford bus services, operated by Greyhound USA, depart from Roanoke Bus Stop station.
Roanoke to Sanford train services, operated by Amtrak, depart from Roanoke station.
The best way to get from Roanoke to Sanford is to fly which takes 3h 19m and costs $65 - $380. Alternatively, you can bus, which costs $150 - $250 and takes 20h 31m, you could also train, which costs $250 - $600 and takes 21h 43m.
What companies run services between Roanoke, VA, USA and Sanford, FL, USA?
Allegiant Air flies from Roanoke Regional Airport-Woodrum Field (ROA) to Orlando Sanford (SFB) twice a week. Alternatively, you can take a bus from Roanoke Bus Stop to Sanford via Lynchburg Transit Center, Richmond, Richmond, and Deltona in around 20h 31m.
- Website
- aa.com
Flights from Roanoke Regional Airport-Woodrum Field to Orlando via Charlotte
- Ave. Duration
- 4h 32m
- When
- Sunday, Monday, Wednesday, Thursday, Friday, and Saturday
- Estimated price
- $65–380
Flights from Roanoke Regional Airport-Woodrum Field to Orlando via Philadelphia
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $100–490
Flights from Roanoke Regional Airport-Woodrum Field to Orlando via Chicago O'Hare
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $130–600
Flights from Roanoke Regional Airport-Woodrum Field to Orlando via Dallas/Ft.Worth
- Ave. Duration
- 6h 51m
- When
- Every day
- Estimated price
- $160–700
- Website
- united.com
Flights from Roanoke Regional Airport-Woodrum Field to Orlando via Washington Dulles
- Ave. Duration
- 4h 49m
- When
- Every day
- Estimated price
- $90–440
Flights from Roanoke Regional Airport-Woodrum Field to Orlando via Chicago O'Hare
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $130–600
- Website
- delta.com
Flights from Roanoke Regional Airport-Woodrum Field to Orlando via Atlanta
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $75–410
Flights from Roanoke Regional Airport-Woodrum Field to Orlando via New York La Guardia
- Ave. Duration
- 7h 33m
- When
- Every day
- Estimated price
- $110–550
- Website
- allegiantair.com
Flights from Roanoke Regional Airport-Woodrum Field to Orlando Sanford
- Ave. Duration
- 1h 50m
- When
- Friday and Monday
- Estimated price
- $65–370
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Roanoke to Lynchburg
- Ave. Duration
- 1h 14m
- Frequency
- Twice daily
- Estimated price
- $16–35
- Website
- Amtrak
Train from Lynchburg to Greensboro
- Ave. Duration
- 2h 9m
- Frequency
- Once daily
- Estimated price
- $30–75
- Website
- Amtrak
Train from Greensboro to Cary
- Ave. Duration
- 1h 27m
- Frequency
- 5 times a day
- Estimated price
- $22–50
- Website
- Amtrak
Train from Cary to Deland
- Ave. Duration
- 12h 37m
- Frequency
- Once daily
- Estimated price
- $180–390
- Website
- Amtrak
Train from Fredericksburg Amtrak to Deland
- Ave. Duration
- 15h 15m
- Frequency
- Once daily
- Estimated price
- $240–550
- Website
- Amtrak
- Phone
- +1 855-724-5411
- [email protected]
- Website
- SunRail
Train from Sand Lake Road to Sanford
- Ave. Duration
- 59 min
- Frequency
- Hourly
- Estimated price
- $3–5
- Website
- SunRail
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Roanoke Bus Stop to Lynchburg Transit Center
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $7–15
- Website
- Greyhound
Bus from Roanoke Bus Stop to Fredericksburg Bus Stop
- Ave. Duration
- 4h 25m
- Frequency
- Once daily
- Estimated price
- $27–55
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Lynchburg Transit Center to Richmond
- Ave. Duration
- 2h 40m
- Frequency
- 4 times a week
- Estimated price
- $20–35
- Schedules at
- Flixbus USA
Bus from Richmond to Deltona
- Ave. Duration
- 14h 15m
- Frequency
- 4 times a week
- Estimated price
- $110–180
- Schedules at
- Flixbus USA
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More Questions & Answers
Roanoke to Sanford bus services, operated by Greyhound USA, arrive at Lynchburg Transit Center station.
Roanoke to Sanford train services, operated by Amtrak, arrive at Lynchburg station.
Yes, the driving distance between Roanoke to Sanford is 669 miles. It takes approximately 11h 51m to drive from Roanoke to Sanford.
There are 107+ hotels available in Sanford.






