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How to get fromRoanoke to Sioux Fallsby plane, bus (Greyhound, Flixbus), train, bus, or car

Find Transport to Sioux Falls

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There are 7 ways to get from Roanoke to Sioux Falls by plane, bus (Greyhound, Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Roanoke Regional Airport-Woodrum Field

    best
    1. Fly from Roanoke Regional Airport-Woodrum Field (ROA) to Sioux Falls (FSD)plane plane ROA - FSD
    7h 45m
    $96–466

  2. Bus via Nashville

    1. Take the bus from Roanoke Bus Stop to Nashville Bus Stationbus bus
    2. Take the bus from Nashville Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    4. Take the bus from Kansas City to Sioux Fallsbus bus
    32h 3m
    $245–393

  3. Train, bus

    1. Take the train from Roanoke to Charlottesvilletrain train
    2. Take the train from Charlottesville to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Kansas Citytrain train
    4. Take the bus from Kansas City to Sioux Fallsbus bus
    43h 14m
    $425–952

  4. Drive  1,179.3 mi

    1. Drive from Roanoke to Sioux Fallscar car 1,179.3 mi
    21h 44m
    $216–311

  5. Drive to Greenbrier Valley Airport, fly

    1. Drive from Roanoke to Greenbrier Valley Airport (LWB)car car
    2. Fly from Greenbrier Valley Airport (LWB) to Sioux Falls (FSD)plane plane LWB - FSD
    10h 13m
    $100–470

  6. Train to Lynchburg Regional Airport, fly

    1. Take the train from Roanoke to Lynchburgtrain train
    2. Fly from Lynchburg Regional Airport (LYH) to Sioux Falls (FSD)plane plane LYH - FSD
    10h 33m
    $107–494

  7. Bus

    1. Take the bus from Salem VDOT Park & Ride to Washington Union Stationbus bus
    2. Take the bus from Washington Union Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Minneapolis Bus Stationbus bus
    4. Take the bus from Minneapolis to Sioux Fallsbus bus
    41h 58m
    $274–446

Roanoke Regional Airport-Woodrum Field (ROA) to Sioux Falls (FSD) flights

Calendar28Weekly Planes
Duration6h 36mAverage Duration
Ticket$90Cheapest Price
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Comparing Your Travel Options

Map of how to get from Roanoke to Sioux Falls.ExpandLaunch map view
  • Distance: 992.1 mi
  • Duration: 7h 45m

What companies run services between Roanoke, VA, USA and Sioux Falls, SD, USA?

United Airlines, American Airlines, and Delta fly from Roanoke Regional Airport-Woodrum Field (ROA) to Sioux Falls (FSD) 4 times a day. Alternatively, you can take a bus from Roanoke Bus Stop to The Bus Stop via Nashville Bus Station, St Louis Bus Station, Kansas City Bus Station, Kansas City, Sioux Falls, and Maple/Career NE corner in around 32h 3m.

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