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How to get fromRochester to Florenceby bus, plane, bus (Greyhound, Flixbus), train, or car

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There are 6 ways to get from Rochester to Florence by bus, plane, bus (Greyhound, Flixbus), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly

    best
    1. Take the bus from Groome Transportation Office - Rochester to Minneapolis / St Paul Airportbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Florence Regional Airport (FLO)plane plane MSP - FLO
    6h 54m
    $170–613

  2. Bus

    1. Take the bus from Rochester to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Florence Bus Stationbus bus
    32h 40m
    $228–417

  3. Bus, train via Milwaukee

    1. Take the bus from Rochester to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    4. Take the train from Petersburg Amtrak Station to Florence Stationtrain train
    36h 23m
    $462–936

  4. Drive 1,176.7 mi

    1. Drive from Rochester to Florencecar car 1,176.7 mi
    21h 29m
    $215–311

  5. Bus, train

    1. Take the bus from Rochester to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    4. Take the train from Petersburg Amtrak Station to Florence Stationtrain train
    38h 11m
    $524–1,089

  6. Bus, train via Raleigh

    1. Take the bus from Rochester to Madisonbus bus
    2. Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus bus
    3. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    4. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus
    38h 36m
    $445–931

Rochester to Florence by bus

Calendar7Weekly Buses
Duration32h 40mAverage Duration
Ticket$228Cheapest Price
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Questions & Answers

Map of how to get from Rochester to Florence.ExpandLaunch map view
  • Distance: 1,106.9 mi
  • Duration: 6h 54m

What companies run services between Rochester, MN, USA and Florence, SC, USA?

You can take a bus from Rochester to Florence Bus Station via Milwaukee, Milwaukee Intermodal Station, Chicago Bus Station, and Atlanta Bus Station in around 32h 40m.

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